Links to all GeneRIF Items | 1045 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 15722794 (CDX2) | Study suggests that CDX2 is a relatively specific marker for tumors with intestinal differentiation; it can be seen in large cell and adenocarcinomas of the lung. |
| 19414376 (CDX2) | High CDX2 expression is associated with non-small cell lung cancer. |
| 22892849 (CDX2) | CDX2 is frequently methylated in lung cancer, and expression of CDX2 is regulated by promoter region hypermethylation. CDX2 may serve as a tumor suppressor in lung cancer and inhibits lung cancer cell proliferation by suppressing Wnt signaling. |
| 24266897 (CDX2) | Discriminated small-cell lung carcinoma from large-cell neuroendocrine lung carcinoma with immunohistochemical markers BAI3, CDX2 and VIL1. |
| 26469326 (CDX2) | CK7, TTF-1 and napsin A are predominantly expressed in primary lung adenocarcinoma patients, with CDX-2 being inconsistently expressed. |