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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

10253

PubMed (Gene Name)

Literature evidence

17369402 (Spry2)

in the context of K-rasG12D-mediated lung tumorigenesis, Sprouty-2 is also up-regulated and functions as a tumor suppressor to limit tumor number and overall tumor burden

18635814 (Spry2)

These results demonstrate that Sprouty 2 overexpression inhibited both lung tumor initiation and subsequent tumor growth.

23650389 (SPRY2)

miR-27a regulates MET, EGFR, and Sprouty2 in lung cancer.

26026961 (SPRY2)

A decrease in SPRY2 and RECK expression by nickel-induced miR-21 may promote invasiveness in lung cancer cells.