Links to all GeneRIF Items | 1017 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25808870 (CDK2) | CP110 plays a mechanistic role in response of lung cancer cells to CDK2 inhibition, especially in the presence of activated KRAS mutations. |
| 26373553 (CDK2) | PIWIL2 has a role in promoting progression of non-small cell lung cancer by inducing CDK2 and Cyclin A expression |
| 26774155 (CDK2) | The authors demonstrated that the CDK2-PAK4 kinase signature may be a useful prognostic indicator and potential target for non-small cell lung cancers, and also proposed that poor outcome subgroup stratified by this classifier may benefit from the recently developed CDK2 and PAK4 inhibitors. |
| 27629878 (CDK2) | Dsg2 knockdown arrests non-small cell lung cancer cell cycle progression via modulation of p27-CDK2 levels. |