Links to all GeneRIF Items | 10075 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25543140 (HUWE1) | we show that HUWE1 stimulates human lung cancer cell invasion through regulating TIAM1 stability. Finally, we demonstrate that HUWE1 and TIAM1 protein levels are inversely correlated in human lung carcinomas |
| 30026863 (HUWE1) | Inactivation of HUWE1 in a human lung cancer cell line inhibited proliferation, colony-forming capacity, and tumorigenicity. Mechanistically, this phenotype was driven by increased p53, which was due to attenuated proteasomal degradation by HUWE1. |
| 31279706 (HUWE1) | LIMCH1 is a negative regulator involved in a new molecular mechanism for the pathogenesis of lung cancer with HUWE1 and p53 |