lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	978
Symbol	CDA
Synonymous	CDD
Full name	cytidine deaminase
Gene description	cytidine aminohydrolase\|cytosine nucleoside deaminase\|small cytidine deaminase
Cytoband	1p36.2-p35
Gene type	protein-coding
Synonymous	MIM:123920; HGNC:HGNC:1712; Ensembl:ENSG00000158825; HPRD:11744; Vega:OTTHUMG00000002845

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.28C>G; p.L10V; 1:20589157-20589157	bone; pelvis	chondrosarcoma	Substitution - Missense
c.182C>A; p.P61Q; 1:20604955-20604955	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.240G>T; p.K80N; 1:20605013-20605013	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.50A>T; p.Q17L; 1:20589179-20589179	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.140G>A; p.G47E; 1:20589269-20589269	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.435C>T; p.T145T; 1:20618562-20618562	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.435C>T; p.T145T; 1:20618562-20618562	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.413G>A; p.G138E; 1:20618540-20618540	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.413G>A; p.G138E; 1:20618540-20618540	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.202C>T; p.R68W; 1:20604975-20604975	skin; scalp	malignant_melanoma	Substitution - Missense
c.325T>G; p.F109V; 1:20618452-20618452	breast	carcinoma	Substitution - Missense
c.250G>A; p.A84T; 1:20605023-20605023	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.241G>T; p.D81Y; 1:20605014-20605014	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.79A>C; p.K27Q; 1:20589208-20589208	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.79A>C; p.K27Q; 1:20589208-20589208	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.79A>C; p.K27Q; 1:20589208-20589208	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.223G>A; p.V75I; 1:20604996-20604996	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.223G>A; p.V75I; 1:20604996-20604996	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.78G>T; p.K26N; 1:20589207-20589207	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.360G>A; p.P120P; 1:20618487-20618487	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.325-1G>C; p.?; 1:20618451-20618451	pancreas	carcinoma; acinar_carcinoma	Unknown
c.262G>A; p.A88T; 1:20605035-20605035	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.262G>A; p.A88T; 1:20605035-20605035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.353C>T; p.T118I; 1:20618480-20618480	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.233G>A; p.G78E; 1:20605006-20605006	skin	malignant_melanoma	Substitution - Missense
c.426G>T; p.L142L; 1:20618553-20618553	prostate	carcinoma	Substitution - coding silent
c.208G>A; p.A70T; 1:20604981-20604981	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.271A>G; p.M91V; 1:20613846-20613846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.203G>T; p.R68L; 1:20604976-20604976	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.234G>A; p.G78G; 1:20605007-20605007	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.417T>C; p.P139P; 1:20618544-20618544	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.434delC; p.Q146fs?; 1:20618561-20618561	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.254T>C; p.I85T; 1:20605027-20605027	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.407C>T; p.S136F; 1:20618534-20618534	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.30G>A; p.L10L; 1:20589159-20589159	skin	malignant_melanoma	Substitution - coding silent
c.348C>T; p.Y116Y; 1:20618475-20618475	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.137_138insG; p.R48fs*20; 1:20589266-20589267	liver	carcinoma	Insertion - Frameshift
c.224T>C; p.V75A; 1:20604997-20604997	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.224T>C; p.V75A; 1:20604997-20604997	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>T; p.I87I; 1:20605034-20605034	skin	malignant_melanoma	Substitution - coding silent
c.52C>T; p.L18L; 1:20589181-20589181	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.261C>T; p.I87I; 1:20605034-20605034	skin	malignant_melanoma	Substitution - coding silent
c.150C>T; p.F50F; 1:20589279-20589279	skin	malignant_melanoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation