Cancer metastasis database

Annotation category 5

Gene information

Gene ID 966
Symbol

CD59

Synonymous

16.3A5|1F5|EJ16|EJ30|EL32|G344|HRF-20|HRF20|MAC-IP|MACIF|MEM43|MIC11|MIN1|MIN2|MIN3|MIRL|MSK21|p18-20

Full name

CD59 molecule, complement regulatory protein

Gene description

1F5 antigen|20 kDa homologous restriction factor|CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)|CD59 glycoprotein|Ly-6-like protein|MEM43 antigen|T cell-activating protein|human leukocyte antigen MIC11|

Cytoband

11p13

Gene type

protein-coding

Synonymous

MIM:107271; HGNC:HGNC:1689; HPRD:00117

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.374G>A; p.S125N; 11:33710139-33710139

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.219C>T; p.N73N; 11:33710294-33710294

breastcarcinomaSubstitution - coding silent

c.220G>A; p.D74N; 11:33710293-33710293

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.307G>A; p.G103S; 11:33710206-33710206

kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.292G>A; p.E98K; 11:33710221-33710221

breastcarcinomaSubstitution - Missense

c.122C>T; p.A41V; 11:33717417-33717417

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.327G>T; p.E109D; 11:33710186-33710186

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.72T>C; p.H24H; 11:33717467-33717467

boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.16G>A; p.G6R; 11:33722430-33722430

skinmalignant_melanomaSubstitution - Missense

c.186C>T; p.N62N; 11:33710327-33710327

stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.31G>A; p.G11R; 11:33722415-33722415

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.24C>G; p.V8V; 11:33722422-33722422

lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.203A>G; p.E68G; 11:33710310-33710310

central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.65C>T; p.S22L; 11:33722381-33722381

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.270G>A; p.K90K; 11:33710243-33710243

urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.270G>A; p.K90K; 11:33710243-33710243

urinary_tract; bladdercarcinomaSubstitution - coding silent