lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	9644
Symbol	SH3PXD2A
Synonymous	FISH\|SH3MD1\|TKS5
Full name	SH3 and PX domains 2A
Gene description	SH3 and PX domain-containing protein 2A\|SH3 multiple domains 1\|adapter protein TKS5\|adaptor protein TKS5\|five SH3 domain-containing protein\|tyrosine kinase substrate with five SH3 domains
Cytoband	10q24.33
Gene type	protein-coding
Synonymous	HGNC:HGNC:23664; Ensembl:ENSG00000107957; HPRD:10228; Vega:OTTHUMG00000018997

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1527C>T; p.G509G; 10:103603607-103603607	pancreas	carcinoma	Substitution - coding silent
c.1527C>T; p.G509G; 10:103603607-103603607	pancreas	carcinoma	Substitution - coding silent
c.2462G>C; p.S821T; 10:103602672-103602672	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1088C>A; p.A363D; 10:103612939-103612939	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.262G>T; p.D88Y; 10:103735776-103735776	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2021C>G; p.S674C; 10:103603113-103603113	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2021C>G; p.S674C; 10:103603113-103603113	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1118G>T; p.R373M; 10:103612909-103612909	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1118G>T; p.R373M; 10:103612909-103612909	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3078C>T; p.P1026P; 10:103602056-103602056	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.307G>C; p.A103P; 10:103724361-103724361	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.581A>C; p.D194A; 10:103661006-103661006	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1714C>T; p.R572W; 10:103603420-103603420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.546C>G; p.N182K; 10:103661041-103661041	skin	malignant_melanoma	Substitution - Missense
c.1714C>T; p.R572W; 10:103603420-103603420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.543G>T; p.E181D; 10:103661044-103661044	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2830G>T; p.V944L; 10:103602304-103602304	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2903C>A; p.A968D; 10:103602231-103602231	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1665_1666GA>TT; p.E555_R556>DW; 10:103603468-103603469	lung	carcinoma; adenocarcinoma	Complex - compound substitution
c.2185C>T; p.R729W; 10:103602949-103602949	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2843C>T; p.A948V; 10:103602291-103602291	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3144G>A; p.V1048V; 10:103601990-103601990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2310G>T; p.E770D; 10:103602824-103602824	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2843C>T; p.A948V; 10:103602291-103602291	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2613C>T; p.N871N; 10:103602521-103602521	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.177C>T; p.P59P; 10:103767146-103767146	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2844G>T; p.A948A; 10:103602290-103602290	skin	malignant_melanoma	Substitution - coding silent
c.3166G>T; p.E1056*; 10:103601968-103601968	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2280C>T; p.L760L; 10:103602854-103602854	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1617A>G; p.S539S; 10:103603517-103603517	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2377G>A; p.D793N; 10:103602757-103602757	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1593C>A; p.D531E; 10:103603541-103603541	prostate	adenoma	Substitution - Missense
c.2833C>T; p.R945W; 10:103602301-103602301	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1088C>T; p.A363V; 10:103612939-103612939	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2040_2042delCTC; p.S682delS; 10:103603092-103603094	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.3075A>C; p.I1025I; 10:103602059-103602059	thyroid	other; neoplasm	Substitution - coding silent
c.2813T>G; p.V938G; 10:103602321-103602321	oesophagus	carcinoma	Substitution - Missense
c.897G>T; p.L299L; 10:103613130-103613130	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2917G>C; p.E973Q; 10:103602217-103602217	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.446C>T; p.A149V; 10:103668634-103668634	ovary	other; neoplasm	Substitution - Missense
c.1288G>A; p.E430K; 10:103605854-103605854	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1562G>A; p.R521Q; 10:103603572-103603572	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1562G>A; p.R521Q; 10:103603572-103603572	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2070G>T; p.L690L; 10:103603064-103603064	pancreas	carcinoma	Substitution - coding silent
c.1631G>A; p.S544N; 10:103603503-103603503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2927C>T; p.T976M; 10:103602207-103602207	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3120C>A; p.F1040L; 10:103602014-103602014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3008G>A; p.R1003H; 10:103602126-103602126	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1443_1444CC>TT; p.(=); 10:103603690-103603691	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.3008G>A; p.R1003H; 10:103602126-103602126	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.141C>A; p.F47L; 10:103801294-103801294	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1090G>A; p.V364M; 10:103612937-103612937	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1090G>A; p.V364M; 10:103612937-103612937	breast	carcinoma	Substitution - Missense
c.2761A>T; p.I921F; 10:103602373-103602373	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1296G>A; p.Q432Q; 10:103605846-103605846	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1094G>T; p.G365V; 10:103612933-103612933	liver	carcinoma	Substitution - Missense
c.1094G>T; p.G365V; 10:103612933-103612933	liver	carcinoma	Substitution - Missense
c.1450C>T; p.R484C; 10:103603684-103603684	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3084C>T; p.S1028S; 10:103602050-103602050	skin	malignant_melanoma	Substitution - coding silent
c.1325G>A; p.R442Q; 10:103605817-103605817	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2447C>T; p.S816L; 10:103602687-103602687	ovary	other; neoplasm	Substitution - Missense
c.1519G>A; p.E507K; 10:103603615-103603615	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1602A>G; p.A534A; 10:103603532-103603532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2447C>T; p.S816L; 10:103602687-103602687	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1602A>G; p.A534A; 10:103603532-103603532	thyroid	other; neoplasm	Substitution - coding silent
c.689C>T; p.S230F; 10:103627118-103627118	skin	malignant_melanoma	Substitution - Missense
c.689C>T; p.S230F; 10:103627118-103627118	skin	malignant_melanoma	Substitution - Missense
c.314T>C; p.V105A; 10:103724354-103724354	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2395G>A; p.A799T; 10:103602739-103602739	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2418C>T; p.T806T; 10:103602716-103602716	skin	malignant_melanoma	Substitution - coding silent
c.305G>T; p.R102L; 10:103735733-103735733	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1959G>T; p.M653I; 10:103603175-103603175	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.909G>T; p.K303N; 10:103613118-103613118	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.539_541delAGG; p.E181delE; 10:103661046-103661048	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.2787C>T; p.F929F; 10:103602347-103602347	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.2787C>T; p.F929F; 10:103602347-103602347	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1996A>G; p.I666V; 10:103603138-103603138	breast	carcinoma	Substitution - Missense
c.1288G>T; p.E430*; 10:103605854-103605854	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2947G>C; p.G983R; 10:103602187-103602187	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1181C>T; p.P394L; 10:103611624-103611624	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.810G>T; p.K270N; 10:103617223-103617223	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.976_978delAAG; p.K326delK; 10:103613049-103613051	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.237C>T; p.I79I; 10:103735801-103735801	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.2192A>T; p.K731M; 10:103602942-103602942	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.237C>T; p.I79I; 10:103735801-103735801	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.197_198insC; p.K68fs*32; 10:103767125-103767126	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.240C>T; p.L80L; 10:103735798-103735798	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1421T>C; p.I474T; 10:103603713-103603713	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1298C>G; p.S433W; 10:103605844-103605844	liver	carcinoma	Substitution - Missense
c.2811G>A; p.A937A; 10:103602323-103602323	oesophagus	carcinoma	Substitution - coding silent
c.1298C>G; p.S433W; 10:103605844-103605844	liver	carcinoma	Substitution - Missense
c.356G>C; p.R119P; 10:103724312-103724312	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1096G>A; p.V366I; 10:103612931-103612931	breast	carcinoma	Substitution - Missense
c.1096G>A; p.V366I; 10:103612931-103612931	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.187G>T; p.G63C; 10:103767136-103767136	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.346G>A; p.E116K; 10:103724322-103724322	skin	malignant_melanoma	Substitution - Missense
c.346G>A; p.E116K; 10:103724322-103724322	skin	malignant_melanoma	Substitution - Missense
c.2103C>T; p.R701R; 10:103603031-103603031	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.110C>T; p.S37F; 10:103801325-103801325	skin	malignant_melanoma	Substitution - Missense
c.1778A>C; p.E593A; 10:103603356-103603356	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.694A>C; p.I232L; 10:103627113-103627113	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.588C>T; p.I196I; 10:103660999-103660999	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.363C>T; p.F121F; 10:103724305-103724305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.786C>T; p.G262G; 10:103617247-103617247	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1515G>T; p.E505D; 10:103603619-103603619	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.541_543delGAG; p.E181delE; 10:103661044-103661046	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.3049C>A; p.L1017I; 10:103602085-103602085	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1500delC; p.S501fs*43; 10:103603634-103603634	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3272C>T; p.P1091L; 10:103601862-103601862	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1500delC; p.S501fs*43; 10:103603634-103603634	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1500delC; p.S501fs*43; 10:103603634-103603634	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1500delC; p.S501fs*43; 10:103603634-103603634	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2255G>A; p.R752H; 10:103602879-103602879	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3020G>A; p.R1007Q; 10:103602114-103602114	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1359C>A; p.N453K; 10:103603775-103603775	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1359C>A; p.N453K; 10:103603775-103603775	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.307G>A; p.A103T; 10:103724361-103724361	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1597C>T; p.P533S; 10:103603537-103603537	skin	malignant_melanoma	Substitution - Missense
c.1359C>A; p.N453K; 10:103603775-103603775	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1359C>A; p.N453K; 10:103603775-103603775	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1359C>A; p.N453K; 10:103603775-103603775	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3076C>T; p.P1026S; 10:103602058-103602058	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.708G>A; p.K236K; 10:103627099-103627099	skin	malignant_melanoma	Substitution - coding silent
c.1862C>A; p.S621*; 10:103603272-103603272	breast	carcinoma	Substitution - Nonsense
c.3234T>C; p.N1078N; 10:103601900-103601900	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2475G>A; p.K825K; 10:103602659-103602659	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3204G>T; p.V1068V; 10:103601930-103601930	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.288C>A; p.P96P; 10:103735750-103735750	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.455_456CC>TT; p.P152L; 10:103668624-103668625	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1559C>T; p.P520L; 10:103603575-103603575	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2966C>T; p.S989F; 10:103602168-103602168	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2326C>T; p.P776S; 10:103602808-103602808	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2957G>A; p.R986Q; 10:103602177-103602177	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.116C>T; p.T39I; 10:103801319-103801319	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1698G>A; p.P566P; 10:103603436-103603436	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3128A>G; p.N1043S; 10:103602006-103602006	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.860C>T; p.A287V; 10:103613167-103613167	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.860C>T; p.A287V; 10:103613167-103613167	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2760_2761insC; p.I921fs*53; 10:103602373-103602374	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.515T>C; p.V172A; 10:103661072-103661072	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1133C>G; p.S378C; 10:103612894-103612894	breast	carcinoma	Substitution - Missense
c.837-1G>A; p.?; 10:103613191-103613191	breast	carcinoma	Unknown
c.1200_1202delTCC; p.P402delP; 10:103611603-103611605	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - In frame
c.3202delG; p.V1068fs*22; 10:103601932-103601932	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1280C>T; p.T427I; 10:103605862-103605862	thyroid	carcinoma	Substitution - Missense
c.2464G>A; p.A822T; 10:103602670-103602670	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2229G>C; p.E743D; 10:103602905-103602905	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3157G>A; p.A1053T; 10:103601977-103601977	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3157G>A; p.A1053T; 10:103601977-103601977	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1684C>T; p.H562Y; 10:103603450-103603450	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.264C>T; p.D88D; 10:103735774-103735774	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2089G>A; p.D697N; 10:103603045-103603045	skin	malignant_melanoma	Substitution - Missense
c.2731G>A; p.V911I; 10:103602403-103602403	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.264C>T; p.D88D; 10:103735774-103735774	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2104G>T; p.G702C; 10:103603030-103603030	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.922G>A; p.G308S; 10:103613105-103613105	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1040A>C; p.K347T; 10:103612987-103612987	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2487G>A; p.S829S; 10:103602647-103602647	breast	carcinoma	Substitution - coding silent
c.2901C>T; p.C967C; 10:103602233-103602233	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3063G>C; p.Q1021H; 10:103602071-103602071	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1472G>A; p.R491Q; 10:103603662-103603662	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1472G>A; p.R491Q; 10:103603662-103603662	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2672A>G; p.N891S; 10:103602462-103602462	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1559C>A; p.P520Q; 10:103603575-103603575	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1453C>T; p.R485C; 10:103603681-103603681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.778G>C; p.E260Q; 10:103617255-103617255	breast	carcinoma	Substitution - Missense
c.1002A>C; p.P334P; 10:103613025-103613025	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.2427A>C; p.E809D; 10:103602707-103602707	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2421G>C; p.K807N; 10:103602713-103602713	breast	carcinoma	Substitution - Missense
c.3244T>C; p.Y1082H; 10:103601890-103601890	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1893_1907del15; p.G633_S637delGSPKS; 10:103603227-103603241	oesophagus	carcinoma; adenocarcinoma	Deletion - In frame
c.2823G>T; p.R941S; 10:103602311-103602311	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1207C>T; p.R403C; 10:103611598-103611598	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1207C>T; p.R403C; 10:103611598-103611598	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2002A>G; p.I668V; 10:103603132-103603132	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1633G>A; p.E545K; 10:103603501-103603501	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.486C>A; p.T162T; 10:103661101-103661101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1208G>A; p.R403H; 10:103611597-103611597	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2181G>A; p.S727S; 10:103602953-103602953	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3091C>T; p.R1031C; 10:103602043-103602043	pancreas	carcinoma	Substitution - Missense
c.2470C>T; p.Q824*; 10:103602664-103602664	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2333C>T; p.T778M; 10:103602801-103602801	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2333C>T; p.T778M; 10:103602801-103602801	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2333C>T; p.T778M; 10:103602801-103602801	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2333C>T; p.T778M; 10:103602801-103602801	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.628G>A; p.E210K; 10:103627179-103627179	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2944C>T; p.R982*; 10:103602190-103602190	skin	malignant_melanoma	Substitution - Nonsense
c.1511A>G; p.K504R; 10:103603623-103603623	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.480C>A; p.D160E; 10:103661107-103661107	thyroid	carcinoma	Substitution - Missense
c.3228_3240del13; p.P1077fs*9; 10:103601894-103601906	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.2663G>A; p.G888D; 10:103602471-103602471	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1795C>T; p.P599S; 10:103603339-103603339	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2784C>G; p.G928G; 10:103602350-103602350	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.368C>T; p.A123V; 10:103724300-103724300	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3306G>A; p.E1102E; 10:103601828-103601828	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation