Cancer metastasis database

Annotation category 5

Gene information

Gene ID 9588
Symbol

PRDX6

Synonymous

1-Cys|AOP2|HEL-S-128m|NSGPx|PRX|aiPLA2|p29

Full name

peroxiredoxin 6

Gene description

1-Cys PRX|1-Cys peroxiredoxin|24 kDa protein|acidic calcium-independent phospholipase A2|antioxidant protein 2|epididymis secretory sperm binding protein Li 128m|liver 2D page spot 40|non-selenium glutathione peroxidase|peroxiredoxin-6|red blood cells pag

Cytoband

1q25.1

Gene type

protein-coding

Synonymous

MIM:602316; HGNC:HGNC:16753; Ensembl:ENSG00000117592; HPRD:03817; Vega:OTTHUMG00000034804

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.608C>T; p.P203L; 1:173487796-173487796

 pancreascarcinomaSubstitution - Missense

c.323G>A; p.R108Q; 1:173485431-173485431

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.472G>A; p.D158N; 1:173486327-173486327

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.282C>T; p.P94P; 1:173485390-173485390

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.480T>G; p.I160M; 1:173486335-173486335

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.416C>T; p.P139L; 1:173486271-173486271

 skinmalignant_melanomaSubstitution - Missense

c.301C>T; p.P101S; 1:173485409-173485409

 skinmalignant_melanomaSubstitution - Missense

c.481C>A; p.L161I; 1:173486336-173486336

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.511G>A; p.A171T; 1:173486366-173486366

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.353A>T; p.D118V; 1:173485461-173485461

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.656G>A; p.R219H; 1:173487844-173487844

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.486G>T; p.R162S; 1:173486341-173486341

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.253G>T; p.D85Y; 1:173485361-173485361

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.429G>C; p.L143L; 1:173486284-173486284

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.286G>T; p.E96*; 1:173485394-173485394

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.286G>T; p.E96*; 1:173485394-173485394

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.316A>G; p.R106G; 1:173485424-173485424

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.502C>T; p.Q168*; 1:173486357-173486357

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.526G>A; p.A176T; 1:173486381-173486381

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.570T>G; p.L190L; 1:173487758-173487758

 pancreascarcinomaSubstitution - coding silent

c.605T>A; p.F202Y; 1:173487793-173487793

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.194A>T; p.N65I; 1:173481424-173481424

 NSNSSubstitution - Missense

c.524T>G; p.V175G; 1:173486379-173486379

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.322C>T; p.R108W; 1:173485430-173485430

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.322C>T; p.R108W; 1:173485430-173485430

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.62G>A; p.G21D; 1:173477459-173477459

 skinmalignant_melanomaSubstitution - Missense

c.286G>A; p.E96K; 1:173485394-173485394

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.371delA; p.K125fs*5; 1:173485479-173485479

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.317G>T; p.R106M; 1:173485425-173485425

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.314A>G; p.D105G; 1:173485422-173485422

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1A>G; p.M1V; 1:173477398-173477398

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.89G>A; p.G30E; 1:173477486-173477486

 central_nervous_system; medullaprimitive_neuroectodermal_tumour-medulloblastoma; desmoplasticSubstitution - Missense

c.606C>T; p.F202F; 1:173487794-173487794

 skinmalignant_melanomaSubstitution - coding silent

c.598A>C; p.K200Q; 1:173487786-173487786

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.451G>A; p.A151T; 1:173486306-173486306

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.356C>T; p.P119L; 1:173485464-173485464

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.477G>T; p.E159D; 1:173486332-173486332

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.113C>T; p.S38F; 1:173481343-173481343

 skinmalignant_melanomaSubstitution - Missense

c.394C>T; p.R132C; 1:173485502-173485502

 skinmalignant_melanomaSubstitution - Missense

c.581C>T; p.P194L; 1:173487769-173487769

 lungcarcinoma; adenocarcinomaSubstitution - Missense