Cancer metastasis database

Annotation category 5

Gene information

Gene ID 9555
Symbol

H2AFY

Synonymous

H2A.y|H2A/y|H2AF12M|H2AFJ|MACROH2A1.1|mH2A1|macroH2A1.2

Full name

H2A histone family, member Y

Gene description

core histone macro-H2A.1|histone H2A.y|histone macroH2A1|histone macroH2A1.1|histone macroH2A1.2|medulloblastoma antigen MU-MB-50.205

Cytoband

5q31.1

Gene type

protein-coding

Synonymous

MIM:610054; HGNC:HGNC:4740; Ensembl:ENSG00000113648; HPRD:13624; Vega:OTTHUMG00000129141

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.78delG; p.R27fs*30; 5:135389016-135389016

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.303C>T; p.A101A; 5:135369580-135369580

 pancreascarcinomaSubstitution - coding silent

c.150C>T; p.A50A; 5:135388944-135388944

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.901G>T; p.A301S; 5:135343312-135343312

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.28T>C; p.S10P; 5:135389066-135389066

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.524C>T; p.T175I; 5:135360561-135360561

 skinmalignant_melanomaSubstitution - Missense

c.253G>A; p.V85M; 5:135370062-135370062

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.381C>T; p.I127I; 5:135369502-135369502

 breastcarcinomaSubstitution - coding silent

c.641C>T; p.A214V; 5:135352993-135352993

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.957C>T; p.N319N; 5:135335138-135335138

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.421C>T; p.Q141*; 5:135369462-135369462

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.778G>A; p.A260T; 5:135345968-135345968

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.543C>T; p.D181D; 5:135360542-135360542

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.998C>T; p.A333V; 5:135335097-135335097

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1017G>T; p.V339V; 5:135335078-135335078

 livercarcinomaSubstitution - coding silent

c.479A>C; p.K160T; 5:135360606-135360606

 livercarcinomaSubstitution - Missense

c.560C>T; p.S187F; 5:135360525-135360525

 skinmalignant_melanomaSubstitution - Missense

c.753G>T; p.K251N; 5:135345993-135345993

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.810C>A; p.A270A; 5:135343403-135343403

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.932T>G; p.F311C; 5:135343281-135343281

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.444delA; p.A149fs*49; 5:135369439-135369439

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.873A>T; p.E291D; 5:135343340-135343340

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.99G>T; p.K33N; 5:135388995-135388995

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.364G>A; p.G122R; 5:135369519-135369519

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.466C>T; p.R156W; 5:135369417-135369417

 pancreascarcinomaSubstitution - Missense

c.438T>C; p.S146S; 5:135369445-135369445

 bone; tibiaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.316T>A; p.L106I; 5:135369567-135369567

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.32C>T; p.T11I; 5:135389062-135389062

 skinmalignant_melanomaSubstitution - Missense

c.70C>T; p.P24S; 5:135389024-135389024

 skinmalignant_melanomaSubstitution - Missense

c.173C>T; p.A58V; 5:135370142-135370142

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.173C>T; p.A58V; 5:135370142-135370142

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1014C>T; p.F338F; 5:135335081-135335081

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.123T>C; p.I41I; 5:135388971-135388971

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.868C>G; p.L290V; 5:135343345-135343345

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.80G>T; p.R27L; 5:135389014-135389014

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.373G>A; p.E125K; 5:135369510-135369510

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1110C>T; p.D370D; 5:135334985-135334985

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.10C>T; p.R4C; 5:135389084-135389084

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.463G>A; p.A155T; 5:135369420-135369420

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.204G>A; p.A68A; 5:135370111-135370111

 soft_tissue; blood_vesselangiosarcomaSubstitution - coding silent

c.153C>T; p.A51A; 5:135388941-135388941

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.513C>T; p.A171A; 5:135360572-135360572

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.513C>T; p.A171A; 5:135360572-135360572

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.352C>T; p.R118W; 5:135369531-135369531

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.25_27delAAG; p.K9delK; 5:135389067-135389069

 stomachadenocarcinomaDeletion - In frame

c.1098G>C; p.M366I; 5:135334997-135334997

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.9C>T; p.S3S; 5:135389085-135389085

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.166C>G; p.L56V; 5:135388928-135388928

 oesophaguscarcinomaSubstitution - Missense

c.162A>T; p.E54D; 5:135388932-135388932

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.162A>T; p.E54D; 5:135388932-135388932

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.8G>A; p.S3N; 5:135389086-135389086

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.288delA; p.G97fs*4; 5:135369595-135369595

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.88C>T; p.R30W; 5:135389006-135389006

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense