lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	947
Symbol	CD34
Synonymous	-
Full name	CD34 molecule
Gene description	CD34 antigen\|hematopoietic progenitor cell antigen CD34
Cytoband	1q32
Gene type	protein-coding
Synonymous	MIM:142230; HGNC:HGNC:1662; Ensembl:ENSG00000174059; HPRD:00790; Vega:OTTHUMG00000036565

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.56C>T; p.A19V; 1:207911025-207911025	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.292G>T; p.V98L; 1:207899197-207899197	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.292G>T; p.V98L; 1:207899197-207899197	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.762C>A; p.S254S; 1:207889206-207889206	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.635G>A; p.R212Q; 1:207889584-207889584	skin	malignant_melanoma	Substitution - Missense
c.684A>C; p.V228V; 1:207889535-207889535	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1040C>T; p.P347L; 1:207887856-207887856	urinary_tract; bladder	carcinoma	Substitution - Missense
c.951G>C; p.W317C; 1:207888703-207888703	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.993G>A; p.T331T; 1:207887903-207887903	skin	malignant_melanoma	Substitution - coding silent
c.567C>T; p.I189I; 1:207897523-207897523	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.754G>T; p.E252*; 1:207889465-207889465	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.950G>A; p.W317*; 1:207888704-207888704	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.950G>A; p.W317*; 1:207888704-207888704	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.114T>A; p.T38T; 1:207899969-207899969	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.759T>G; p.I253M; 1:207889209-207889209	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>T; p.N126N; 1:207899111-207899111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1002T>G; p.G334G; 1:207887894-207887894	breast	carcinoma	Substitution - coding silent
c.18C>T; p.G6G; 1:207911063-207911063	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.298A>C; p.T100P; 1:207899191-207899191	kidney	other; neoplasm	Substitution - Missense
c.76C>T; p.L26L; 1:207911005-207911005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.97C>T; p.L33F; 1:207899986-207899986	skin	malignant_melanoma	Substitution - Missense
c.806_807insA; p.L270fs*8; 1:207889161-207889162	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.202G>A; p.G68R; 1:207899881-207899881	skin	malignant_melanoma	Substitution - Missense
c.327T>C; p.S109S; 1:207899162-207899162	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.72T>C; p.S24S; 1:207911009-207911009	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.293T>C; p.V98A; 1:207899196-207899196	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.136C>A; p.Q46K; 1:207899947-207899947	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1070G>A; p.R357Q; 1:207887826-207887826	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.86G>A; p.G29E; 1:207899997-207899997	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1086C>T; p.N362N; 1:207887810-207887810	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.688T>C; p.S230P; 1:207889531-207889531	liver	carcinoma	Substitution - Missense
c.867G>T; p.K289N; 1:207888787-207888787	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.867G>T; p.K289N; 1:207888787-207888787	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.909C>G; p.V303V; 1:207888745-207888745	breast	carcinoma	Substitution - coding silent
c.936G>A; p.M312I; 1:207888718-207888718	skin	malignant_melanoma	Substitution - Missense
c.302C>G; p.S101*; 1:207899187-207899187	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.217C>T; p.H73Y; 1:207899866-207899866	pancreas	carcinoma	Substitution - Missense
c.406C>T; p.P136S; 1:207899083-207899083	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.868A>T; p.T290S; 1:207888786-207888786	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.904G>T; p.A302S; 1:207888750-207888750	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1069C>T; p.R357*; 1:207887827-207887827	breast	carcinoma	Substitution - Nonsense
c.1069C>T; p.R357*; 1:207887827-207887827	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.709G>A; p.E237K; 1:207889510-207889510	breast	carcinoma	Substitution - Missense
c.1004G>T; p.G335V; 1:207887892-207887892	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1092C>T; p.T364T; 1:207887804-207887804	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.42G>A; p.P14P; 1:207911039-207911039	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1142C>T; p.A381V; 1:207887754-207887754	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1066A>T; p.N356Y; 1:207887830-207887830	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1066A>T; p.N356Y; 1:207887830-207887830	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.586A>G; p.T196A; 1:207897504-207897504	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.488C>A; p.S163*; 1:207899001-207899001	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.205A>G; p.S69G; 1:207899878-207899878	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.319A>G; p.N107D; 1:207899170-207899170	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.499A>G; p.I167V; 1:207898990-207898990	prostate	adenoma	Substitution - Missense
c.714G>A; p.V238V; 1:207889505-207889505	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1025G>T; p.G342V; 1:207887871-207887871	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.138G>T; p.Q46H; 1:207899945-207899945	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.752C>A; p.T251K; 1:207889467-207889467	breast	carcinoma	Substitution - Missense
c.470C>T; p.P157L; 1:207899019-207899019	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.620G>A; p.G207E; 1:207889599-207889599	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1100C>A; p.A367D; 1:207887796-207887796	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.20C>T; p.A7V; 1:207911061-207911061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.544G>A; p.E182K; 1:207897546-207897546	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.780G>A; p.M260I; 1:207889188-207889188	skin	malignant_melanoma	Substitution - Missense
c.1052G>A; p.G351E; 1:207887844-207887844	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.717G>T; p.R239S; 1:207889502-207889502	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.393G>A; p.E131E; 1:207899096-207899096	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.22C>T; p.R8C; 1:207911059-207911059	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.330C>T; p.V110V; 1:207899159-207899159	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.218A>G; p.H73R; 1:207899865-207899865	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.765C>T; p.S255S; 1:207889203-207889203	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1032G>A; p.G344G; 1:207887864-207887864	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.949T>C; p.W317R; 1:207888705-207888705	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.517-4A>G; p.?; 1:207897577-207897577	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.370C>A; p.P124T; 1:207899119-207899119	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1005A>T; p.G335G; 1:207887891-207887891	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.890C>T; p.S297L; 1:207888764-207888764	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.470C>A; p.P157H; 1:207899019-207899019	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.85G>T; p.G29W; 1:207899998-207899998	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.529T>C; p.C177R; 1:207897561-207897561	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation