lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	9260
Symbol	PDLIM7
Synonymous	LMP1\|LMP3
Full name	PDZ and LIM domain 7 (enigma)
Gene description	1110003B01Rik\|LIM domain protein\|LMP\|Lim mineralization protein 3\|PDZ and LIM domain protein 7\|protein enigma
Cytoband	5q35.3
Gene type	protein-coding
Synonymous	MIM:605903; HGNC:HGNC:22958; Ensembl:ENSG00000196923; HPRD:10436; Vega:OTTHUMG00000130853

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.872G>T; p.G291V; 5:177488246-177488246	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.901T>A; p.Y301N; 5:177488217-177488217	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1210G>C; p.D404H; 5:177483944-177483944	breast	carcinoma	Substitution - Missense
c.428C>T; p.A143V; 5:177491117-177491117	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.524G>A; p.G175D; 5:177491021-177491021	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1233_1234CC>TT; p.R412C; 5:177483920-177483921	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.747G>A; p.P249P; 5:177489515-177489515	breast	carcinoma	Substitution - coding silent
c.551A>C; p.E184A; 5:177490891-177490891	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1270A>T; p.T424S; 5:177483884-177483884	thyroid	other; neoplasm	Substitution - Missense
c.546G>A; p.P182P; 5:177490896-177490896	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.816G>T; p.G272G; 5:177489446-177489446	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.818delG; p.G273fs*84; 5:177489444-177489444	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.816G>T; p.G272G; 5:177489446-177489446	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.818delG; p.G273fs*84; 5:177489444-177489444	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.536T>G; p.M179R; 5:177490906-177490906	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.36A>G; p.A12A; 5:177496477-177496477	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.403C>T; p.P135S; 5:177491142-177491142	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1084G>A; p.V362M; 5:177484157-177484157	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.909G>A; p.P303P; 5:177488209-177488209	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.267C>T; p.S89S; 5:177492417-177492417	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.264G>A; p.Q88Q; 5:177492420-177492420	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.502C>T; p.R168C; 5:177491043-177491043	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.502C>T; p.R168C; 5:177491043-177491043	large_intestine; colon	carcinoma	Substitution - Missense
c.381C>T; p.S127S; 5:177491824-177491824	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.127G>A; p.G43R; 5:177492647-177492647	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.708G>A; p.P236P; 5:177489554-177489554	breast	carcinoma	Substitution - coding silent
c.572+2T>C; p.?; 5:177490868-177490868	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.708G>A; p.P236P; 5:177489554-177489554	thyroid	other; neoplasm	Substitution - coding silent
c.1006C>T; p.R336C; 5:177488112-177488112	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.648C>G; p.P216P; 5:177489614-177489614	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1286C>T; p.A429V; 5:177483868-177483868	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1278C>T; p.F426F; 5:177483876-177483876	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1342C>T; p.L448F; 5:177483676-177483676	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1040_1042delAGA; p.K347delK; 5:177488076-177488078	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Deletion - In frame
c.1349A>G; p.K450R; 5:177483669-177483669	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1177G>C; p.E393Q; 5:177483977-177483977	breast	carcinoma	Substitution - Missense
c.136G>A; p.V46M; 5:177492638-177492638	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.471G>A; p.P157P; 5:177491074-177491074	central_nervous_system; brain	glioma	Substitution - coding silent
c.1007G>A; p.R336H; 5:177488111-177488111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.81C>T; p.P27P; 5:177496432-177496432	breast	carcinoma	Substitution - coding silent
c.1194G>A; p.T398T; 5:177483960-177483960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1194G>A; p.T398T; 5:177483960-177483960	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1022_1023insCCCAGCT; p.A342fs*54; 5:177488095-177488096	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.984C>T; p.F328F; 5:177488134-177488134	skin	malignant_melanoma	Substitution - coding silent
c.935G>T; p.G312V; 5:177488183-177488183	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1169G>A; p.R390Q; 5:177484072-177484072	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.976G>A; p.A326T; 5:177488142-177488142	thyroid	other; neoplasm	Substitution - Missense
c.1001A>G; p.D334G; 5:177488117-177488117	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1264C>T; p.H422Y; 5:177483890-177483890	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1129A>C; p.R377R; 5:177484112-177484112	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1306G>C; p.E436Q; 5:177483712-177483712	urinary_tract; bladder	carcinoma	Substitution - Missense
c.266G>T; p.S89I; 5:177492418-177492418	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.662G>A; p.R221H; 5:177489600-177489600	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.24G>A; p.L8L; 5:177496489-177496489	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.596C>G; p.P199R; 5:177489809-177489809	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1166A>C; p.E389A; 5:177484075-177484075	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.898G>T; p.A300S; 5:177488220-177488220	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1050+3G>T; p.?; 5:177488065-177488065	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1224C>T; p.D408D; 5:177483930-177483930	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1368T>C; p.H456H; 5:177483650-177483650	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1152C>T; p.G384G; 5:177484089-177484089	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1152C>T; p.G384G; 5:177484089-177484089	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1271C>G; p.T424S; 5:177483883-177483883	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1359C>T; p.A453A; 5:177483659-177483659	pancreas	carcinoma	Substitution - coding silent
c.1359C>T; p.A453A; 5:177483659-177483659	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1350G>C; p.K450N; 5:177483668-177483668	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1359C>T; p.A453A; 5:177483659-177483659	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1063G>A; p.A355T; 5:177484178-177484178	pancreas	carcinoma	Substitution - Missense
c.159C>T; p.I53I; 5:177492615-177492615	thyroid	carcinoma	Substitution - coding silent
c.1257C>T; p.F419F; 5:177483897-177483897	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation