lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	9235
Symbol	IL32
Synonymous	IL-32alpha\|IL-32beta\|IL-32delta\|IL-32gamma\|NK4\|TAIF\|TAIFa\|TAIFb\|TAIFc\|TAIFd
Full name	interleukin 32
Gene description	interleukin-32\|interleukin-32 eta\|interleukin-32 small\|interleukin-32 theta\|natural killer cell transcript 4\|natural killer cells protein 4\|tumor necrosis factor alpha-inducing factor
Cytoband	16p13.3
Gene type	protein-coding
Synonymous	MIM:606001; HGNC:HGNC:16830; Ensembl:ENSG00000008517; HPRD:09346; Vega:OTTHUMG00000167498

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.563A>T; p.K188I; 16:3069351-3069351	skin	malignant_melanoma	Substitution - Missense
c.315T>G; p.C105W; 16:3069103-3069103	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.107G>T; p.R36L; 16:3067606-3067606	skin	malignant_melanoma	Substitution - Missense
c.560C>T; p.S187L; 16:3069348-3069348	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.250G>A; p.G84S; 16:3069038-3069038	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.373G>A; p.G125R; 16:3069161-3069161	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.498C>T; p.Y166Y; 16:3069286-3069286	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.498C>T; p.Y166Y; 16:3069286-3069286	breast	carcinoma	Substitution - coding silent
c.515_516insG; p.D172fs*12; 16:3069303-3069304	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.515_516insG; p.D172fs*12; 16:3069303-3069304	pleura	pulmonary_blastoma	Insertion - Frameshift
c.515_516insG; p.D172fs*12; 16:3069303-3069304	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.515_516insG; p.D172fs*12; 16:3069303-3069304	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.327G>A; p.M109I; 16:3069115-3069115	skin	malignant_melanoma	Substitution - Missense
c.176C>T; p.A59V; 16:3068214-3068214	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.522G>A; p.E174E; 16:3069310-3069310	skin	malignant_melanoma	Substitution - coding silent
c.514G>C; p.D172H; 16:3069302-3069302	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.251G>A; p.G84D; 16:3069039-3069039	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.7T>G; p.F3V; 16:3065818-3065818	skin	malignant_melanoma	Substitution - Missense
c.378T>C; p.V126V; 16:3069166-3069166	thyroid	other; neoplasm	Substitution - coding silent
c.378T>C; p.V126V; 16:3069166-3069166	thyroid	other; neoplasm	Substitution - coding silent
c.378T>C; p.V126V; 16:3069166-3069166	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.280G>A; p.D94N; 16:3069068-3069068	skin	malignant_melanoma	Substitution - Missense
c.474C>G; p.L158L; 16:3069262-3069262	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.521A>T; p.E174V; 16:3069309-3069309	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.508C>T; p.R170W; 16:3069296-3069296	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	breast	carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	urinary_tract; bladder	carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.523G>T; p.E175*; 16:3069311-3069311	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.508_509insG; p.D172fs*12; 16:3069296-3069297	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.46G>A; p.A16T; 16:3067407-3067407	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.444C>T; p.F148F; 16:3069232-3069232	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.411G>T; p.L137L; 16:3069199-3069199	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.411G>T; p.L137L; 16:3069199-3069199	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.444C>T; p.F148F; 16:3069232-3069232	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.220G>C; p.E74Q; 16:3069008-3069008	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.50G>A; p.R17Q; 16:3067411-3067411	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.463C>T; p.L155L; 16:3069251-3069251	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.505C>A; p.P169T; 16:3069293-3069293	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	liver	carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	thyroid	other; neoplasm	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>G; p.D172G; 16:3069303-3069303	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.107G>A; p.R36H; 16:3067606-3067606	central_nervous_system; brain	glioma; astrocytoma_Grade_III	Substitution - Missense
c.509_510insG; p.D172fs*12; 16:3069297-3069298	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Insertion - Frameshift
c.509_510insG; p.D172fs*12; 16:3069297-3069298	pancreas	carcinoid-endocrine_tumour; islet_cell	Insertion - Frameshift
c.54G>A; p.M18I; 16:3067415-3067415	skin; mucosal	malignant_melanoma	Substitution - Missense
c.566G>A; p.189; 16:3069354-3069354	skin	malignant_melanoma	Substitution - coding silent
c.566G>A; p.189; 16:3069354-3069354	skin	malignant_melanoma	Substitution - coding silent
c.231A>G; p.R77R; 16:3069019-3069019	breast	carcinoma	Substitution - coding silent
c.231A>G; p.R77R; 16:3069019-3069019	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.260C>T; p.S87F; 16:3069048-3069048	skin	malignant_melanoma	Substitution - Missense
c.223A>T; p.K75*; 16:3069011-3069011	skin	malignant_melanoma	Substitution - Nonsense
c.462T>G; p.S154S; 16:3069250-3069250	liver	carcinoma	Substitution - coding silent
c.141G>A; p.E47E; 16:3068010-3068010	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.462T>G; p.S154S; 16:3069250-3069250	liver	carcinoma	Substitution - coding silent
c.257G>A; p.R86K; 16:3069045-3069045	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.489_490CC>TT; p.Q164*; 16:3069277-3069278	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.467C>T; p.S156L; 16:3069255-3069255	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.21C>T; p.L7L; 16:3067382-3067382	skin	malignant_melanoma	Substitution - coding silent
c.16G>A; p.V6I; 16:3067377-3067377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation