lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	917
Symbol	CD3G
Synonymous	CD3-GAMMA\|IMD17\|T3G
Full name	CD3g molecule, gamma (CD3-TCR complex)
Gene description	CD3g antigen, gamma polypeptide (TiT3 complex)\|CD3g molecule, epsilon (CD3-TCR complex)\|T-cell antigen receptor complex, gamma subunit of T3\|T-cell receptor T3 gamma chain\|T-cell surface glycoprotein CD3 gamma chain
Cytoband	11q23
Gene type	protein-coding
Synonymous	MIM:186740; HGNC:HGNC:1675; HPRD:07037

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.161C>G; p.T54R; 11:118349824-118349824	urinary_tract; bladder	carcinoma	Substitution - Missense
c.161C>G; p.T54R; 11:118349824-118349824	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.3G>A; p.M1I; 11:118344426-118344426	skin	malignant_melanoma	Substitution - Missense
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.369C>T; p.I123I; 11:118350613-118350613	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	stomach	adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.369C>T; p.I123I; 11:118350613-118350613	skin	malignant_melanoma	Substitution - coding silent
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.205delA; p.K71fs*40; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.183G>T; p.M61I; 11:118349846-118349846	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.112G>T; p.E38*; 11:118349775-118349775	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.134C>G; p.T45S; 11:118349797-118349797	skin	malignant_melanoma	Substitution - Missense
c.484-10T>C; p.?; 11:118352394-118352394	liver	carcinoma	Unknown
c.355C>A; p.L119I; 11:118350599-118350599	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.464C>T; p.P155L; 11:118351652-118351652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.492G>A; p.K164K; 11:118352412-118352412	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.547T>A; p.*183R; 11:118352467-118352467	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Nonstop extension
c.223G>A; p.G75R; 11:118349886-118349886	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.527G>A; p.G176E; 11:118352447-118352447	skin; extremity	malignant_melanoma	Substitution - Missense
c.356T>C; p.L119P; 11:118350600-118350600	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.186C>T; p.I62I; 11:118349849-118349849	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.204_205insA; p.W72fs*6; 11:118349867-118349868	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.204_205insA; p.W72fs*6; 11:118349867-118349868	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.27delC; p.L10fs*35; 11:118344450-118344450	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.145G>A; p.E49K; 11:118349808-118349808	breast	carcinoma	Substitution - Missense
c.390T>C; p.A130A; 11:118350634-118350634	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.391G>T; p.V131F; 11:118350635-118350635	urinary_tract; bladder	carcinoma	Substitution - Missense
c.391G>T; p.V131F; 11:118350635-118350635	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.10G>A; p.G4R; 11:118344433-118344433	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.10G>A; p.G4R; 11:118344433-118344433	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.320G>A; p.C107Y; 11:118350564-118350564	breast	carcinoma	Substitution - Missense
c.266G>A; p.G89E; 11:118349929-118349929	skin	malignant_melanoma	Substitution - Missense
c.159C>G; p.I53M; 11:118349822-118349822	breast	carcinoma	Substitution - Missense
c.122C>T; p.S41L; 11:118349785-118349785	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.532C>A; p.Q178K; 11:118352452-118352452	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.305G>C; p.R102T; 11:118349968-118349968	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.406A>G; p.I136V; 11:118350650-118350650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.205A>T; p.K69*; 11:118349868-118349868	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.205A>T; p.K69*; 11:118349868-118349868	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation