Cancer metastasis database

Annotation category 5

Gene information

Gene ID 9077
Symbol

DIRAS3

Synonymous

ARHI|NOEY2

Full name

DIRAS family, GTP-binding RAS-like 3

Gene description

GTP-binding protein Di-Ras3|distinct subgroup of the Ras family member 3|ras homolog gene family, member I|rho-related GTP-binding protein RhoI

Cytoband

1p31

Gene type

protein-coding

Synonymous

MIM:605193; HGNC:HGNC:687; Ensembl:ENSG00000162595; HPRD:05547

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.551C>G; p.T184S; 1:68046747-68046747

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.285C>T; p.G95G; 1:68047013-68047013

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.429T>G; p.H143Q; 1:68046869-68046869

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.155C>T; p.T52M; 1:68047143-68047143

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.665T>A; p.L222Q; 1:68046633-68046633

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.417T>C; p.G139G; 1:68046881-68046881

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.199C>T; p.L67L; 1:68047099-68047099

 skinmalignant_melanomaSubstitution - coding silent

c.46C>G; p.R16G; 1:68047252-68047252

 pleurapulmonary_blastomaSubstitution - Missense

c.261G>A; p.L87L; 1:68047037-68047037

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - coding silent

c.148A>G; p.K50E; 1:68047150-68047150

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.612C>T; p.T204T; 1:68046686-68046686

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.123G>T; p.V41V; 1:68047175-68047175

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.612C>T; p.T204T; 1:68046686-68046686

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.612C>T; p.T204T; 1:68046686-68046686

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.114C>T; p.Y38Y; 1:68047184-68047184

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.123G>A; p.V41V; 1:68047175-68047175

 skinmalignant_melanomaSubstitution - coding silent

c.288C>T; p.D96D; 1:68047010-68047010

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.649A>G; p.N217D; 1:68046649-68046649

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.597G>A; p.K199K; 1:68046701-68046701

 skinmalignant_melanomaSubstitution - coding silent

c.337G>A; p.V113I; 1:68046961-68046961

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.221A>T; p.Y74F; 1:68047077-68047077

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.177C>T; p.S59S; 1:68047121-68047121

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.522T>A; p.N174K; 1:68046776-68046776

 skinmalignant_melanomaSubstitution - Missense

c.308G>T; p.R103L; 1:68046990-68046990

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.296G>A; p.R99H; 1:68047002-68047002

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.59T>A; p.L20Q; 1:68047239-68047239

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.296G>A; p.R99H; 1:68047002-68047002

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.296G>C; p.R99P; 1:68047002-68047002

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.402C>A; p.I134I; 1:68046896-68046896

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.322C>T; p.R108W; 1:68046976-68046976

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.514G>A; p.E172K; 1:68046784-68046784

 skinmalignant_melanomaSubstitution - Missense

c.286G>A; p.D96N; 1:68047012-68047012

 skin; acralmalignant_melanomaSubstitution - Missense

c.298G>A; p.A100T; 1:68047000-68047000

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.298G>A; p.A100T; 1:68047000-68047000

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.298G>A; p.A100T; 1:68047000-68047000

 NSNSSubstitution - Missense

c.298G>A; p.A100T; 1:68047000-68047000

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.298G>A; p.A100T; 1:68047000-68047000

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.298G>A; p.A100T; 1:68047000-68047000

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.435C>T; p.F145F; 1:68046863-68046863

 skinmalignant_melanomaSubstitution - coding silent

c.386C>T; p.A129V; 1:68046912-68046912

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.660G>A; p.E220E; 1:68046638-68046638

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.186C>T; p.F62F; 1:68047112-68047112

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.610A>G; p.T204A; 1:68046688-68046688

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.654C>T; p.T218T; 1:68046644-68046644

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.64G>A; p.A22T; 1:68047234-68047234

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.690A>G; p.*230W; 1:68046608-68046608

 stomachcarcinoma; adenocarcinomaNonstop extension

c.240C>A; p.C80*; 1:68047058-68047058

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.628G>T; p.E210*; 1:68046670-68046670

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.660G>T; p.E220D; 1:68046638-68046638

 breastcarcinomaSubstitution - Missense

c.207C>T; p.T69T; 1:68047091-68047091

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.330C>A; p.H110Q; 1:68046968-68046968

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.69G>A; p.L23L; 1:68047229-68047229

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.643A>G; p.M215V; 1:68046655-68046655

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.120C>T; p.V40V; 1:68047178-68047178

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.120C>T; p.V40V; 1:68047178-68047178

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.339C>T; p.V113V; 1:68046959-68046959

 breastcarcinomaSubstitution - coding silent

c.370C>T; p.L124L; 1:68046928-68046928

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.394G>A; p.E132K; 1:68046904-68046904

 skin; upper_armmalignant_melanomaSubstitution - Missense

c.628G>C; p.E210Q; 1:68046670-68046670

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.90G>T; p.K30N; 1:68047208-68047208

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.289G>A; p.G97S; 1:68047009-68047009

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.63C>T; p.P21P; 1:68047235-68047235

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.628G>A; p.E210K; 1:68046670-68046670

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.628G>A; p.E210K; 1:68046670-68046670

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.664C>G; p.L222V; 1:68046634-68046634

 ovaryother; neoplasmSubstitution - Missense

c.308G>A; p.R103H; 1:68046990-68046990

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.545C>T; p.A182V; 1:68046753-68046753

 livercarcinomaSubstitution - Missense

c.545C>T; p.A182V; 1:68046753-68046753

 livercarcinomaSubstitution - Missense

c.279G>A; p.K93K; 1:68047019-68047019

 skinmalignant_melanomaSubstitution - coding silent

c.529T>G; p.F177V; 1:68046769-68046769

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.204G>A; p.P68P; 1:68047094-68047094

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.116G>A; p.R39H; 1:68047182-68047182

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense