lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	9071
Symbol	CLDN10
Synonymous	CPETRL3\|OSP-L
Full name	claudin 10
Gene description	OSP-like protein\|claudin-10
Cytoband	13q31-q34
Gene type	protein-coding
Synonymous	HGNC:HGNC:2033; Ensembl:ENSG00000134873; HPRD:13063; Vega:OTTHUMG00000017217

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.142T>C; p.W48R; 13:95433975-95433975	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.184C>T; p.R62*; 13:95434017-95434017	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.184C>T; p.R62*; 13:95434017-95434017	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.133C>T; p.Q45*; 13:95433966-95433966	skin	malignant_melanoma	Substitution - Nonsense
c.58G>A; p.V20I; 13:95433891-95433891	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.546T>C; p.S182S; 13:95577318-95577318	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.127G>A; p.V43I; 13:95433960-95433960	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.185G>T; p.R62L; 13:95434018-95434018	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.153C>T; p.C51C; 13:95433986-95433986	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.131A>G; p.Y44C; 13:95433964-95433964	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.287T>C; p.L96P; 13:95560204-95560204	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.581G>A; p.G194E; 13:95577914-95577914	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.432C>A; p.F144L; 13:95560437-95560437	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.162C>G; p.N54K; 13:95433995-95433995	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.432C>A; p.F144L; 13:95560437-95560437	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.432C>A; p.F144L; 13:95560437-95560437	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.183C>A; p.C61*; 13:95434016-95434016	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.584C>T; p.A195V; 13:95577917-95577917	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.358A>C; p.I120L; 13:95560275-95560275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.260T>G; p.L87R; 13:95560177-95560177	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.247G>A; p.A83T; 13:95560164-95560164	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.668A>C; p.N223T; 13:95578001-95578001	skin	malignant_melanoma	Substitution - Missense
c.185G>A; p.R62Q; 13:95434018-95434018	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.185G>A; p.R62Q; 13:95434018-95434018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.40G>A; p.G14R; 13:95433873-95433873	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.539C>G; p.S180*; 13:95577311-95577311	ovary	other; neoplasm	Substitution - Nonsense
c.173C>A; p.S58Y; 13:95434006-95434006	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.40G>A; p.G14R; 13:95433873-95433873	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.605G>A; p.R202Q; 13:95577938-95577938	skin	malignant_melanoma	Substitution - Missense
c.669T>A; p.N223K; 13:95578002-95578002	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.605G>A; p.R202Q; 13:95577938-95577938	skin	malignant_melanoma	Substitution - Missense
c.164C>T; p.A55V; 13:95433997-95433997	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.383G>T; p.C128F; 13:95560388-95560388	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.312C>T; p.V104V; 13:95560229-95560229	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.189G>A; p.P63P; 13:95434022-95434022	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.340A>G; p.I114V; 13:95560257-95560257	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.590C>A; p.S197Y; 13:95577923-95577923	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.582G>A; p.G194G; 13:95577915-95577915	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.388A>G; p.M130V; 13:95560393-95560393	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.640A>G; p.T214A; 13:95577973-95577973	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.616C>T; p.H206Y; 13:95577949-95577949	skin	malignant_melanoma	Substitution - Missense
c.282T>C; p.F94F; 13:95560199-95560199	liver	carcinoma	Substitution - coding silent
c.436G>C; p.D146H; 13:95560441-95560441	breast	carcinoma	Substitution - Missense
c.96G>A; p.T32T; 13:95433929-95433929	bone; femur	chondrosarcoma	Substitution - coding silent
c.11C>T; p.A4V; 13:95433844-95433844	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.11C>T; p.A4V; 13:95433844-95433844	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.11C>T; p.A4V; 13:95433844-95433844	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.179A>G; p.H60R; 13:95434012-95434012	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.95C>T; p.T32M; 13:95433928-95433928	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.72G>A; p.T24T; 13:95433905-95433905	breast	carcinoma	Substitution - coding silent
c.275C>T; p.S92F; 13:95560192-95560192	skin	malignant_melanoma	Substitution - Missense
c.98G>A; p.R33Q; 13:95433931-95433931	skin	malignant_melanoma	Substitution - Missense
c.98G>A; p.R33Q; 13:95433931-95433931	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246C>T; p.I82I; 13:95560163-95560163	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.628G>C; p.D210H; 13:95577961-95577961	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.504A>G; p.S168S; 13:95577276-95577276	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.43G>A; p.G15R; 13:95433876-95433876	breast	carcinoma	Substitution - Missense
c.186A>G; p.R62R; 13:95434019-95434019	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.475G>A; p.A159T; 13:95577247-95577247	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.55C>T; p.L19F; 13:95433888-95433888	skin	malignant_melanoma	Substitution - Missense
c.183C>T; p.C61C; 13:95434016-95434016	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.620G>A; p.G207D; 13:95577953-95577953	skin	malignant_melanoma	Substitution - Missense
c.480G>T; p.L160L; 13:95577252-95577252	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.162C>T; p.N54N; 13:95433995-95433995	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.222A>G; p.I74M; 13:95560139-95560139	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.222A>G; p.I74M; 13:95560139-95560139	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation