Cancer metastasis database

Annotation category 5

Gene information

Gene ID 9
Symbol

NAT1

Synonymous

AAC1|MNAT|NAT-1|NATI

Full name

N-acetyltransferase 1 (arylamine N-acetyltransferase)

Gene description

N-acetyltransferase type 1|arylamide acetylase 1|arylamine N-acetyltransferase 1|monomorphic arylamine N-acetyltransferase

Cytoband

8p22

Gene type

protein-coding

Synonymous

MIM:108345; HGNC:HGNC:7645; Ensembl:ENSG00000171428; HPRD:00149; Vega:OTTHUMG00000097001

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.771T>C; p.T257T; 8:18222818-18222818

 NSNSSubstitution - coding silent

c.680C>T; p.T227I; 8:18222727-18222727

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.353A>G; p.N118S; 8:18222400-18222400

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.336G>T; p.V112V; 8:18222383-18222383

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.864T>C; p.F288F; 8:18222911-18222911

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.259A>T; p.T87S; 8:18222306-18222306

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.784G>T; p.E262*; 8:18222831-18222831

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.419G>A; p.G140E; 8:18222466-18222466

 skin; neckmalignant_melanomaSubstitution - Missense

c.503A>C; p.Q168P; 8:18222550-18222550

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.456G>T; p.L152F; 8:18222503-18222503

 breastcarcinomaSubstitution - Missense

c.818T>G; p.I273S; 8:18222865-18222865

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.347G>A; p.G116D; 8:18222394-18222394

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.469G>A; p.G157R; 8:18222516-18222516

 breastcarcinomaSubstitution - Missense

c.465G>T; p.E155D; 8:18222512-18222512

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.465G>T; p.E155D; 8:18222512-18222512

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.169G>T; p.D57Y; 8:18222216-18222216

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.240C>T; p.T80T; 8:18222287-18222287

 skinmalignant_melanomaSubstitution - coding silent

c.425A>G; p.D142G; 8:18222472-18222472

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.425A>G; p.D142G; 8:18222472-18222472

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.197G>A; p.G66E; 8:18222244-18222244

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.208C>T; p.Q70*; 8:18222255-18222255

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.26G>T; p.R9I; 8:18222073-18222073

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.26G>T; p.R9I; 8:18222073-18222073

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.662C>T; p.S221L; 8:18222709-18222709

 skinmalignant_melanomaSubstitution - Missense

c.486C>G; p.D162E; 8:18222533-18222533

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.191G>A; p.R64Q; 8:18222238-18222238

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.67A>G; p.T23A; 8:18222114-18222114

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.628C>G; p.Q210E; 8:18222675-18222675

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.788T>G; p.I263R; 8:18222835-18222835

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.305G>A; p.S102N; 8:18222352-18222352

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.445G>A; p.V149I; 8:18222492-18222492

 skinmalignant_melanomaSubstitution - Missense

c.536A>C; p.D179A; 8:18222583-18222583

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.716T>G; p.L239R; 8:18222763-18222763

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense