Cancer metastasis database

Annotation category 5

Gene information

Gene ID 8772
Symbol

FADD

Synonymous

GIG3|MORT1

Full name

Fas (TNFRSF6)-associated via death domain

Gene description

FAS-associated death domain protein|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor induced toxicity|mediator of receptor-induced toxicity

Cytoband

11q13.3

Gene type

protein-coding

Synonymous

MIM:602457; HGNC:HGNC:3573; Ensembl:ENSG00000168040; HPRD:03909; Vega:OTTHUMG00000167264

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.474G>T; p.V158V; 11:70206320-70206320

large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.172G>T; p.G58W; 11:70203631-70203631

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.101G>A; p.R34H; 11:70203560-70203560

stomachadenocarcinomaSubstitution - Missense

c.401C>T; p.P134L; 11:70206247-70206247

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.410T>A; p.L137Q; 11:70206256-70206256

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.55G>A; p.E19K; 11:70203514-70203514

urinary_tract; bladdercarcinomaSubstitution - Missense

c.466G>A; p.A156T; 11:70206312-70206312

livercarcinomaSubstitution - Missense

c.466G>A; p.A156T; 11:70206312-70206312

livercarcinomaSubstitution - Missense

c.377T>A; p.I126N; 11:70206223-70206223

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.342G>C; p.R114S; 11:70206188-70206188

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.331G>C; p.D111H; 11:70206177-70206177

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.331G>C; p.D111H; 11:70206177-70206177

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.289C>T; p.L97L; 11:70206135-70206135

pancreascarcinomaSubstitution - coding silent

c.375G>T; p.K125N; 11:70206221-70206221

pancreasNSSubstitution - Missense

c.621G>A; p.A207A; 11:70206467-70206467

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.427G>T; p.E143*; 11:70206273-70206273

haematopoietic_and_lymphoid_tissue; spleenlymphoid_neoplasm; marginal_zone_lymphomaSubstitution - Nonsense

c.48G>A; p.S16S; 11:70203507-70203507

urinary_tract; bladdercarcinomaSubstitution - coding silent

c.186C>T; p.L62L; 11:70203645-70203645

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.581C>T; p.S194F; 11:70206427-70206427

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.378C>T; p.I126I; 11:70206224-70206224

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.449_450delAC; p.T151fs*24; 11:70206295-70206296

oesophagus; lower_thirdcarcinoma; adenocarcinomaDeletion - Frameshift

c.252delG; p.A86fs*52; 11:70203711-70203711

large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.81C>A; p.C27*; 11:70203540-70203540

lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense