lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	8658
Symbol	TNKS
Synonymous	ARTD5\|PARP-5a\|PARP5A\|PARPL\|TIN1\|TINF1\|TNKS1\|pART5
Full name	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Gene description	ADP-ribosyltransferase diphtheria toxin-like 5\|TANK1\|TNKS-1\|TRF1-interacting ankyrin-related ADP-ribose polymerase\|poly [ADP-ribose] polymerase 5A\|tankyrase I\|tankyrase-1
Cytoband	8p23.1
Gene type	protein-coding
Synonymous	MIM:603303; HGNC:HGNC:11941; Ensembl:ENSG00000173273; HPRD:04490; Vega:OTTHUMG00000090481

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.2708C>T; p.A903V; 8:9748088-9748088	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2708C>T; p.A903V; 8:9748088-9748088	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2758G>A; p.A920T; 8:9748138-9748138	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2758G>A; p.A920T; 8:9748138-9748138	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.2758G>A; p.A920T; 8:9748138-9748138	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.235C>T; p.R79*; 8:9556174-9556174	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2156T>G; p.V719G; 8:9733287-9733287	breast	carcinoma	Substitution - Missense
c.1744G>A; p.A582T; 8:9710215-9710215	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.3019G>C; p.A1007P; 8:9751795-9751795	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2850T>G; p.A950A; 8:9751626-9751626	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2498C>T; p.T833I; 8:9735049-9735049	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2842A>G; p.I948V; 8:9751618-9751618	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3447+2T>C; p.?; 8:9764792-9764792	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.2899C>T; p.P967S; 8:9751675-9751675	skin	malignant_melanoma	Substitution - Missense
c.1219C>T; p.H407Y; 8:9706203-9706203	skin	malignant_melanoma	Substitution - Missense
c.3554G>T; p.G1185V; 8:9766239-9766239	central_nervous_system; thalamus	glioma; astrocytoma_Grade_II	Substitution - Missense
c.2863G>T; p.A955S; 8:9751639-9751639	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3662G>A; p.S1221N; 8:9766347-9766347	small_intestine	carcinoid-endocrine_tumour	Substitution - Missense
c.2617C>T; p.P873S; 8:9735460-9735460	skin; leg	malignant_melanoma; superficial_spreading	Substitution - Missense
c.3091A>G; p.I1031V; 8:9752564-9752564	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.600G>T; p.R200S; 8:9556539-9556539	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2813C>T; p.T938M; 8:9748193-9748193	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2088C>T; p.R696R; 8:9730976-9730976	skin	malignant_melanoma	Substitution - coding silent
c.1945G>A; p.D649N; 8:9726664-9726664	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1586C>T; p.A529V; 8:9709962-9709962	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3121G>A; p.E1041K; 8:9752594-9752594	skin	malignant_melanoma	Substitution - Missense
c.712A>T; p.M238L; 8:9580197-9580197	skin	malignant_melanoma	Substitution - Missense
c.2913A>G; p.V971V; 8:9751689-9751689	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.11C>T; p.S4L; 8:9555950-9555950	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2900C>A; p.P967H; 8:9751676-9751676	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.11C>T; p.S4L; 8:9555950-9555950	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.416C>T; p.S139L; 8:9556355-9556355	urinary_tract; bladder	carcinoma	Substitution - Missense
c.235C>G; p.R79G; 8:9556174-9556174	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2676C>T; p.Y892Y; 8:9748056-9748056	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.871A>G; p.I291V; 8:9580356-9580356	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2993C>G; p.P998R; 8:9751769-9751769	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.90A>G; p.P30P; 8:9556029-9556029	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2121T>A; p.G707G; 8:9731009-9731009	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.90A>G; p.P30P; 8:9556029-9556029	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.600G>A; p.R200R; 8:9556539-9556539	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2177C>T; p.S726L; 8:9733308-9733308	skin	malignant_melanoma	Substitution - Missense
c.2865C>T; p.A955A; 8:9751641-9751641	skin	malignant_melanoma	Substitution - coding silent
c.3940G>A; p.E1314K; 8:9776692-9776692	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1516delA; p.T508fs*33; 8:9708430-9708430	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2200G>C; p.E734Q; 8:9733331-9733331	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1516delA; p.T508fs*33; 8:9708430-9708430	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1516delA; p.T508fs*33; 8:9708430-9708430	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1937G>A; p.R646H; 8:9726656-9726656	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3045G>A; p.A1015A; 8:9751821-9751821	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2838C>T; p.D946D; 8:9751614-9751614	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1516delA; p.T508fs*33; 8:9708430-9708430	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3045G>A; p.A1015A; 8:9751821-9751821	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2362G>A; p.D788N; 8:9734913-9734913	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1937G>A; p.R646H; 8:9726656-9726656	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3009C>T; p.A1003A; 8:9751785-9751785	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3620T>G; p.M1207R; 8:9766305-9766305	skin	malignant_melanoma	Substitution - Missense
c.1324G>A; p.A442T; 8:9706865-9706865	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1387T>C; p.L463L; 8:9706928-9706928	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3240C>A; p.I1080I; 8:9761602-9761602	breast	carcinoma	Substitution - coding silent
c.2516C>T; p.T839I; 8:9735067-9735067	skin; ear	malignant_melanoma	Substitution - Missense
c.401C>T; p.S134F; 8:9556340-9556340	breast	carcinoma	Substitution - Missense
c.994delG; p.G332fs*9; 8:9615677-9615677	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.1114C>A; p.P372T; 8:9704669-9704669	NS	NS	Substitution - Missense
c.366C>A; p.G122G; 8:9556305-9556305	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2608G>A; p.G870S; 8:9735451-9735451	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.145A>G; p.T49A; 8:9556084-9556084	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.145A>G; p.T49A; 8:9556084-9556084	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3166G>T; p.V1056L; 8:9761528-9761528	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2410G>T; p.D804Y; 8:9734961-9734961	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1505T>C; p.L502S; 8:9708419-9708419	skin	malignant_melanoma	Substitution - Missense
c.3132G>T; p.R1044R; 8:9752605-9752605	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.236G>T; p.R79L; 8:9556175-9556175	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.236G>T; p.R79L; 8:9556175-9556175	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2599G>A; p.D867N; 8:9735442-9735442	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1958G>A; p.R653Q; 8:9726677-9726677	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2593G>A; p.A865T; 8:9735436-9735436	bone; pelvis	chondrosarcoma	Substitution - Missense
c.580G>A; p.D194N; 8:9556519-9556519	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147C>T; p.R383*; 8:9704702-9704702	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1147C>T; p.R383*; 8:9704702-9704702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1147C>T; p.R383*; 8:9704702-9704702	breast	carcinoma	Substitution - Nonsense
c.1339C>T; p.R447C; 8:9706880-9706880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1147C>T; p.R383*; 8:9704702-9704702	skin	malignant_melanoma	Substitution - Nonsense
c.1147C>T; p.R383*; 8:9704702-9704702	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1147C>T; p.R383*; 8:9704702-9704702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1147C>T; p.R383*; 8:9704702-9704702	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1031+1G>T; p.?; 8:9679988-9679988	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.2874A>G; p.P958P; 8:9751650-9751650	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3084C>G; p.D1028E; 8:9752557-9752557	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1386A>G; p.T462T; 8:9706927-9706927	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1386A>G; p.T462T; 8:9706927-9706927	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3283C>A; p.P1095T; 8:9763155-9763155	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.625G>A; p.A209T; 8:9556564-9556564	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3474G>C; p.L1158F; 8:9765718-9765718	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1287T>C; p.N429N; 8:9706828-9706828	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2851T>G; p.L951V; 8:9751627-9751627	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2339A>G; p.N780S; 8:9734890-9734890	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2407delG; p.D804fs*49; 8:9734958-9734958	stomach	adenocarcinoma	Deletion - Frameshift
c.1274G>T; p.G425V; 8:9706815-9706815	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2407delG; p.D804fs*49; 8:9734958-9734958	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3703C>T; p.P1235S; 8:9766388-9766388	skin	malignant_melanoma	Substitution - Missense
c.2833-9delT; p.?; 8:9751600-9751600	stomach	adenocarcinoma	Unknown
c.67G>A; p.G23R; 8:9556006-9556006	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.3010G>A; p.V1004I; 8:9751786-9751786	thyroid	carcinoma	Substitution - Missense
c.1579-1G>A; p.?; 8:9709954-9709954	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3356A>G; p.Q1119R; 8:9763228-9763228	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3446G>A; p.R1149Q; 8:9764789-9764789	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2126A>C; p.D709A; 8:9731014-9731014	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2922C>T; p.A974A; 8:9751698-9751698	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1159_1161delCTT; p.L389delL; 8:9704714-9704716	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.443C>A; p.S148*; 8:9556382-9556382	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2164C>T; p.H722Y; 8:9733295-9733295	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1658delA; p.N555fs*5; 8:9710034-9710034	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3227G>A; p.R1076H; 8:9761589-9761589	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2758G>T; p.A920S; 8:9748138-9748138	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1100G>A; p.G367E; 8:9680793-9680793	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.912C>T; p.H304H; 8:9615595-9615595	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.605T>G; p.V202G; 8:9556544-9556544	thyroid	other; neoplasm	Substitution - Missense
c.99C>A; p.P33P; 8:9556038-9556038	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1557G>A; p.P519P; 8:9708471-9708471	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3854A>G; p.N1285S; 8:9770219-9770219	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3696A>G; p.T1232T; 8:9766381-9766381	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3854A>G; p.N1285S; 8:9770219-9770219	breast	carcinoma	Substitution - Missense
c.3741A>G; p.R1247R; 8:9770106-9770106	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3126C>T; p.H1042H; 8:9752599-9752599	skin	malignant_melanoma	Substitution - coding silent
c.673+6A>G; p.?; 8:9556618-9556618	ovary	other; neoplasm	Unknown
c.2061C>T; p.P687P; 8:9730949-9730949	central_nervous_system; brain	glioma	Substitution - coding silent
c.2057C>T; p.T686M; 8:9730945-9730945	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1109C>T; p.S370L; 8:9704664-9704664	skin	malignant_melanoma	Substitution - Missense
c.2238G>A; p.A746A; 8:9733369-9733369	ovary	other; neoplasm	Substitution - coding silent
c.3074C>T; p.A1025V; 8:9752547-9752547	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2232T>C; p.N744N; 8:9733363-9733363	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3383C>G; p.T1128S; 8:9764726-9764726	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1879G>T; p.A627S; 8:9720503-9720503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3397A>G; p.R1133G; 8:9764740-9764740	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3322T>G; p.L1108V; 8:9763194-9763194	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3966C>T; p.A1322A; 8:9776718-9776718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3966C>T; p.A1322A; 8:9776718-9776718	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3071-1G>C; p.?; 8:9752543-9752543	lung	carcinoma; adenocarcinoma	Unknown
c.886G>C; p.D296H; 8:9580371-9580371	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.157C>A; p.L53M; 8:9556096-9556096	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2598G>T; p.Q866H; 8:9735441-9735441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2058G>A; p.T686T; 8:9730946-9730946	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2872C>A; p.P958T; 8:9751648-9751648	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1610G>A; p.R537H; 8:9709986-9709986	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3643G>T; p.A1215S; 8:9766328-9766328	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3850G>A; p.V1284I; 8:9770215-9770215	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3381T>C; p.S1127S; 8:9764724-9764724	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3447+3A>G; p.?; 8:9764793-9764793	pancreas	carcinoma	Unknown
c.3464A>T; p.N1155I; 8:9765708-9765708	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1385C>T; p.T462I; 8:9706926-9706926	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.84G>T; p.P28P; 8:9556023-9556023	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2075C>T; p.A692V; 8:9730963-9730963	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.308C>T; p.P103L; 8:9556247-9556247	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3878T>C; p.V1293A; 8:9770243-9770243	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2733C>G; p.A911A; 8:9748113-9748113	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.3481C>T; p.R1161W; 8:9765725-9765725	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3964G>C; p.A1322P; 8:9776716-9776716	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3599G>A; p.R1200Q; 8:9766284-9766284	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3967G>A; p.A1323T; 8:9776719-9776719	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3130C>T; p.R1044W; 8:9752603-9752603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3130C>T; p.R1044W; 8:9752603-9752603	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1166T>G; p.L389R; 8:9704721-9704721	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1327G>A; p.A443T; 8:9706868-9706868	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1202+2T>C; p.?; 8:9704759-9704759	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.3616G>A; p.G1206R; 8:9766301-9766301	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.532G>A; p.A178T; 8:9556471-9556471	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3811G>A; p.A1271T; 8:9770176-9770176	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3073G>T; p.A1025S; 8:9752546-9752546	skin	malignant_melanoma	Substitution - Missense
c.3630C>T; p.A1210A; 8:9766315-9766315	skin	malignant_melanoma	Substitution - coding silent
c.898+1G>A; p.?; 8:9580384-9580384	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.583G>A; p.V195M; 8:9556522-9556522	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1732C>T; p.H578Y; 8:9710203-9710203	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3008C>T; p.A1003V; 8:9751784-9751784	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1148G>A; p.R383Q; 8:9704703-9704703	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1148G>A; p.R383Q; 8:9704703-9704703	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1392C>T; p.V464V; 8:9706933-9706933	bone; pelvis	chondrosarcoma	Substitution - coding silent
c.1925G>A; p.S642N; 8:9726644-9726644	skin; trunk	malignant_melanoma	Substitution - Missense
c.3739A>G; p.R1247G; 8:9766424-9766424	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2070C>T; p.F690F; 8:9730958-9730958	breast	carcinoma	Substitution - coding silent
c.2070C>T; p.F690F; 8:9730958-9730958	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1936C>T; p.R646C; 8:9726655-9726655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3543G>C; p.M1181I; 8:9765787-9765787	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1609C>T; p.R537C; 8:9709985-9709985	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1565A>T; p.H522L; 8:9708479-9708479	skin	malignant_melanoma	Substitution - Missense
c.3538C>T; p.R1180C; 8:9765782-9765782	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2960C>T; p.S987L; 8:9751736-9751736	skin	malignant_melanoma	Substitution - Missense
c.1657_1658insA; p.N555fs*2; 8:9710033-9710034	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2047C>T; p.R683W; 8:9730935-9730935	skin	malignant_melanoma	Substitution - Missense
c.858G>A; p.L286L; 8:9580343-9580343	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1121A>G; p.H374R; 8:9704676-9704676	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3846G>A; p.P1282P; 8:9770211-9770211	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3702C>T; p.C1234C; 8:9766387-9766387	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3420C>T; p.G1140G; 8:9764763-9764763	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3631G>A; p.G1211R; 8:9766316-9766316	prostate	carcinoma	Substitution - Missense
c.3389G>T; p.R1130L; 8:9764732-9764732	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3204A>G; p.I1068M; 8:9761566-9761566	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2533+1G>T; p.?; 8:9735085-9735085	lung	carcinoma; adenocarcinoma	Unknown
c.420T>G; p.S140S; 8:9556359-9556359	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1667A>G; p.K556R; 8:9710043-9710043	liver	carcinoma	Substitution - Missense
c.2713A>T; p.T905S; 8:9748093-9748093	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1667A>G; p.K556R; 8:9710043-9710043	liver	carcinoma	Substitution - Missense
c.3152A>G; p.Q1051R; 8:9752625-9752625	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1820G>A; p.C607Y; 8:9720444-9720444	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.2494G>T; p.D832Y; 8:9735045-9735045	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1618G>C; p.V540L; 8:9709994-9709994	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3445C>T; p.R1149*; 8:9764788-9764788	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.3445C>T; p.R1149*; 8:9764788-9764788	breast	carcinoma	Substitution - Nonsense
c.2913_2916delAGTG; p.S973fs*3; 8:9751689-9751692	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2775T>A; p.H925Q; 8:9748155-9748155	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3658A>G; p.K1220E; 8:9766343-9766343	bone; rib	chondrosarcoma	Substitution - Missense
c.2200G>A; p.E734K; 8:9733331-9733331	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1885C>T; p.Q629*; 8:9720509-9720509	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2453G>C; p.R818T; 8:9735004-9735004	skin	malignant_melanoma	Substitution - Missense
c.1180G>A; p.D394N; 8:9704735-9704735	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation