Cancer metastasis database

Annotation category 5

Gene information

Gene ID 8490
Symbol

RGS5

Synonymous

MST092|MST106|MST129|MSTP032|MSTP092|MSTP106|MSTP129

Full name

regulator of G-protein signaling 5

Gene description

-

Cytoband

1q23.1

Gene type

protein-coding

Synonymous

MIM:603276; HGNC:HGNC:10001; Ensembl:ENSG00000143248; Ensembl:ENSG00000232995; HPRD:04471; Vega:OTTHUMG00000034441

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.399C>G; p.H133Q; 1:163147489-163147489

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.516C>T; p.R172R; 1:163147372-163147372

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.274G>C; p.E92Q; 1:163152660-163152660

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.156-1G>A; p.?; 1:163161977-163161977

 skinmalignant_melanomaUnknown

c.350A>G; p.Y117C; 1:163152584-163152584

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.315C>T; p.S105S; 1:163152619-163152619

 skinmalignant_melanomaSubstitution - coding silent

c.315C>T; p.S105S; 1:163152619-163152619

 skinmalignant_melanomaSubstitution - coding silent

c.440C>T; p.S147F; 1:163147448-163147448

 skinmalignant_melanomaSubstitution - Missense

c.440C>T; p.S147F; 1:163147448-163147448

 skinmalignant_melanomaSubstitution - Missense

c.521A>C; p.E174A; 1:163147367-163147367

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.91G>A; p.D31N; 1:163168322-163168322

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.455A>G; p.D152G; 1:163147433-163147433

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.493G>A; p.D165N; 1:163147395-163147395

 breastcarcinomaSubstitution - Missense

c.161C>G; p.S54W; 1:163161971-163161971

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.130_131CC>AA; p.P44K; 1:163168282-163168283

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.205C>A; p.L69M; 1:163161927-163161927

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.470G>C; p.R157T; 1:163147418-163147418

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.27C>T; p.P9P; 1:163202809-163202809

 skinmalignant_melanomaSubstitution - coding silent

c.243C>T; p.F81F; 1:163152691-163152691

 skinmalignant_melanomaSubstitution - coding silent

c.333G>T; p.E111D; 1:163152601-163152601

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.76C>A; p.L26I; 1:163168337-163168337

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.44+8C>G; p.?; 1:163202784-163202784

 stomachcarcinoma; adenocarcinomaUnknown

c.156-1G>C; p.?; 1:163161977-163161977

 breastcarcinomaUnknown

c.369G>A; p.T123T; 1:163152565-163152565

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.481C>A; p.L161M; 1:163147407-163147407

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.514C>T; p.R172C; 1:163147374-163147374

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.70G>T; p.G24*; 1:163168343-163168343

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.514C>T; p.R172C; 1:163147374-163147374

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.506G>A; p.R169H; 1:163147382-163147382

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.506G>A; p.R169H; 1:163147382-163147382

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.544T>C; p.*182Q; 1:163147344-163147344

 lungcarcinoma; squamous_cell_carcinomaNonstop extension

c.35G>A; p.C12Y; 1:163202801-163202801

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.447C>T; p.S149S; 1:163147441-163147441

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.105C>T; p.D35D; 1:163168308-163168308

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.220G>A; p.G74R; 1:163152714-163152714

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.81C>T; p.L27L; 1:163168332-163168332

 skinmalignant_melanomaSubstitution - coding silent

c.303G>A; p.K101K; 1:163152631-163152631

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.220G>T; p.G74*; 1:163152714-163152714

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.331G>A; p.E111K; 1:163152603-163152603

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.191C>T; p.S64F; 1:163161941-163161941

 skinmalignant_melanomaSubstitution - Missense

c.430G>C; p.V144L; 1:163147458-163147458

 pancreascarcinomaSubstitution - Missense

c.168C>T; p.D56D; 1:163161964-163161964

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.35G>T; p.C12F; 1:163202801-163202801

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.84G>T; p.Q28H; 1:163168329-163168329

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.523T>G; p.F175V; 1:163147365-163147365

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.65A>G; p.K22R; 1:163168348-163168348

 skinmalignant_melanomaSubstitution - Missense

c.515G>A; p.R172H; 1:163147373-163147373

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.379A>T; p.K127*; 1:163152555-163152555

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.483G>T; p.L161L; 1:163147405-163147405

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.309C>G; p.I103M; 1:163152625-163152625

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.411C>T; p.D137D; 1:163147477-163147477

 skinmalignant_melanomaSubstitution - coding silent

c.431T>G; p.V144G; 1:163147457-163147457

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.460G>T; p.A154S; 1:163147428-163147428

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.423G>A; p.K141K; 1:163147465-163147465

 skinmalignant_melanomaSubstitution - coding silent

c.185G>A; p.R62H; 1:163161947-163161947

 stomachcarcinoma; adenocarcinomaSubstitution - Missense