Cancer metastasis database

Annotation category 5

Gene information

Gene ID 84879
Symbol

MFSD2A

Synonymous

MFSD2|NLS1

Full name

major facilitator superfamily domain containing 2A

Gene description

major facilitator superfamily domain-containing protein 2A|sodium-dependent LPC symporter 1|sodium-dependent lysophosphatidylcholine symporter 1

Cytoband

1p34.2

Gene type

protein-coding

Synonymous

MIM:614397; HGNC:HGNC:25897; Ensembl:ENSG00000168389; HPRD:07861; Vega:OTTHUMG00000009293

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1353-7C>G; p.?; 1:39968562-39968562

 livercarcinomaUnknown

c.1470A>G; p.K490K; 1:39968686-39968686

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1241A>T; p.H414L; 1:39968366-39968366

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1042C>T; p.Q348*; 1:39967658-39967658

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.832C>T; p.P278S; 1:39966837-39966837

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1050C>A; p.F350L; 1:39967666-39967666

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.858G>A; p.R286R; 1:39966863-39966863

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.113A>G; p.K38R; 1:39957106-39957106

 skinmalignant_melanomaSubstitution - Missense

c.1529+2T>G; p.?; 1:39968747-39968747

 ovarycarcinoma; serous_carcinomaUnknown

c.378C>T; p.A126A; 1:39965235-39965235

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.373C>A; p.L125M; 1:39965230-39965230

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.651T>C; p.N217N; 1:39965951-39965951

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.651T>C; p.N217N; 1:39965951-39965951

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.567G>A; p.V189V; 1:39965867-39965867

 skinmalignant_melanomaSubstitution - coding silent

c.340C>T; p.R114C; 1:39958812-39958812

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.870C>A; p.S290R; 1:39966875-39966875

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.870C>A; p.S290R; 1:39966875-39966875

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.304C>T; p.L102F; 1:39958776-39958776

 skin; neckmalignant_melanomaSubstitution - Missense

c.293C>T; p.P98L; 1:39958765-39958765

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.744C>T; p.V248V; 1:39966630-39966630

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.229-3C>T; p.?; 1:39958698-39958698

 stomachcarcinoma; adenocarcinomaUnknown

c.542C>A; p.S181Y; 1:39965535-39965535

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1215G>T; p.M405I; 1:39968340-39968340

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.977G>A; p.R326H; 1:39967135-39967135

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.977G>A; p.R326H; 1:39967135-39967135

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.322C>T; p.P108S; 1:39958794-39958794

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1243C>T; p.L415L; 1:39968368-39968368

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.874G>A; p.G292S; 1:39966879-39966879

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.617G>C; p.G206A; 1:39965917-39965917

 breastcarcinomaSubstitution - Missense

c.82G>A; p.A28T; 1:39955374-39955374

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.873C>T; p.H291H; 1:39966878-39966878

 ovaryother; neoplasmSubstitution - coding silent

c.321C>T; p.S107S; 1:39958793-39958793

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.873C>T; p.H291H; 1:39966878-39966878

 ovaryother; neoplasmSubstitution - coding silent

c.1157C>T; p.A386V; 1:39967865-39967865

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1157C>T; p.A386V; 1:39967865-39967865

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1157C>T; p.A386V; 1:39967865-39967865

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1157C>T; p.A386V; 1:39967865-39967865

 pancreascarcinomaSubstitution - Missense

c.1542C>A; p.S514R; 1:39969517-39969517

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.837C>T; p.I279I; 1:39966842-39966842

 skin; trunkmalignant_melanoma; nodularSubstitution - coding silent

c.289G>A; p.D97N; 1:39958761-39958761

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1013T>G; p.L338R; 1:39967629-39967629

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1477C>T; p.P493S; 1:39968693-39968693

 skinmalignant_melanomaSubstitution - Missense

c.1495C>T; p.R499W; 1:39968711-39968711

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.713C>T; p.T238M; 1:39966013-39966013

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.390C>T; p.Y130Y; 1:39965247-39965247

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.523G>A; p.E175K; 1:39965516-39965516

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.686C>A; p.T229K; 1:39965986-39965986

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.350C>G; p.P117R; 1:39958822-39958822

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.556C>T; p.R186W; 1:39965549-39965549

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.556C>T; p.R186W; 1:39965549-39965549

 skinmalignant_melanomaSubstitution - Missense

c.556C>T; p.R186W; 1:39965549-39965549

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1430C>T; p.A477V; 1:39968646-39968646

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1430C>T; p.A477V; 1:39968646-39968646

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.10G>A; p.G4R; 1:39955302-39955302

 skinmalignant_melanomaSubstitution - Missense

c.605G>A; p.G202E; 1:39965905-39965905

 skinmalignant_melanomaSubstitution - Missense

c.754A>C; p.I252L; 1:39966640-39966640

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1005C>T; p.A335A; 1:39967163-39967163

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.999C>A; p.L333L; 1:39967157-39967157

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.919G>A; p.A307T; 1:39966924-39966924

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.477G>C; p.T159T; 1:39965334-39965334

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.874G>T; p.G292C; 1:39966879-39966879

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.507C>T; p.T169T; 1:39965500-39965500

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.874G>T; p.G292C; 1:39966879-39966879

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.204G>T; p.Q68H; 1:39957197-39957197

 livercarcinomaSubstitution - Missense

c.204G>T; p.Q68H; 1:39957197-39957197

 livercarcinomaSubstitution - Missense

c.199C>A; p.L67I; 1:39957192-39957192

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.490C>T; p.P164S; 1:39965483-39965483

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.158G>A; p.G53E; 1:39957151-39957151

 skinmalignant_melanomaSubstitution - Missense

c.6C>A; p.A2A; 1:39955298-39955298

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.369G>T; p.T123T; 1:39965226-39965226

 pancreascarcinomaSubstitution - coding silent

c.369G>T; p.T123T; 1:39965226-39965226

 pancreascarcinoma; ductal_carcinomaSubstitution - coding silent

c.955T>C; p.C319R; 1:39967113-39967113

 prostatecarcinomaSubstitution - Missense

c.17G>T; p.G6V; 1:39955309-39955309

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.27C>A; p.S9R; 1:39955319-39955319

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.411C>T; p.P137P; 1:39965268-39965268

 skinmalignant_melanomaSubstitution - coding silent

c.350C>T; p.P117L; 1:39958822-39958822

 skinmalignant_melanomaSubstitution - Missense

c.918G>A; p.L306L; 1:39966923-39966923

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - coding silent

c.1233C>T; p.D411D; 1:39968358-39968358

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.150A>G; p.A50A; 1:39957143-39957143

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.150A>G; p.A50A; 1:39957143-39957143

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.441C>T; p.Y147Y; 1:39965298-39965298

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1553G>A; p.C518Y; 1:39969528-39969528

 ovaryother; neoplasmSubstitution - Missense

c.983A>T; p.E328V; 1:39967141-39967141

 pancreasNSSubstitution - Missense

c.987C>T; p.F329F; 1:39967145-39967145

 skinmalignant_melanomaSubstitution - coding silent

c.987C>T; p.F329F; 1:39967145-39967145

 skinmalignant_melanomaSubstitution - coding silent

c.230T>G; p.V77G; 1:39958702-39958702

 breastcarcinomaSubstitution - Missense

c.1534G>A; p.E512K; 1:39969509-39969509

 skin; trunkmalignant_melanoma; nodularSubstitution - Missense

c.1234G>A; p.D412N; 1:39968359-39968359

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1234G>A; p.D412N; 1:39968359-39968359

 skinmalignant_melanomaSubstitution - Missense

c.1410G>A; p.L470L; 1:39968626-39968626

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.198C>T; p.F66F; 1:39957191-39957191

 skinmalignant_melanomaSubstitution - coding silent

c.149C>G; p.A50G; 1:39957142-39957142

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1496G>T; p.R499L; 1:39968712-39968712

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.97G>T; p.E33*; 1:39957090-39957090

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.97G>T; p.E33*; 1:39957090-39957090

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.856C>T; p.R286W; 1:39966861-39966861

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.856C>T; p.R286W; 1:39966861-39966861

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense