lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	84168
Symbol	ANTXR1
Synonymous	ATR\|GAPO\|TEM8
Full name	anthrax toxin receptor 1
Gene description	2310008J16Rik\|2810405N18Rik\|tumor endothelial marker 8
Cytoband	2p13.1
Gene type	protein-coding
Synonymous	MIM:606410; HGNC:HGNC:21014; Ensembl:ENSG00000169604; HPRD:05913; Vega:OTTHUMG00000129575

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.468T>A; p.D156E; 2:69073077-69073077	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1166G>A; p.G389E; 2:69181862-69181862	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.225-2A>T; p.?; 2:69044740-69044740	lung	carcinoma; adenocarcinoma	Unknown
c.664G>A; p.E222K; 2:69090880-69090880	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1676C>T; p.P559L; 2:69245466-69245466	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.528C>A; p.Y176*; 2:69075625-69075625	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.6C>T; p.A2A; 2:69013505-69013505	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.253T>C; p.F85L; 2:69044770-69044770	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.242C>T; p.S81F; 2:69044759-69044759	skin	malignant_melanoma	Substitution - Missense
c.1596C>T; p.P532P; 2:69245386-69245386	thyroid	other; neoplasm	Substitution - coding silent
c.749G>A; p.R250H; 2:69102887-69102887	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1601C>T; p.P534L; 2:69245391-69245391	skin	malignant_melanoma	Substitution - Missense
c.492+10G>A; p.?; 2:69073111-69073111	stomach	carcinoma; adenocarcinoma	Unknown
c.1670G>C; p.R557P; 2:69245460-69245460	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.492+10G>A; p.?; 2:69073111-69073111	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1653G>T; p.R551S; 2:69245443-69245443	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1030C>T; p.P344S; 2:69152247-69152247	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1261C>T; p.P421S; 2:69182568-69182568	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1511C>G; p.S504C; 2:69245301-69245301	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.295A>G; p.R99G; 2:69044812-69044812	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1329C>T; p.P443P; 2:69182636-69182636	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.76G>A; p.A26T; 2:69013575-69013575	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.142A>G; p.I48V; 2:69013641-69013641	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1131_1132GG>AA; p.V378I; 2:69181827-69181828	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.900C>T; p.N300N; 2:69124592-69124592	stomach	adenocarcinoma	Substitution - coding silent
c.900C>T; p.N300N; 2:69124592-69124592	skin	malignant_melanoma	Substitution - coding silent
c.1345_1346delCC; p.P449fs*17; 2:69182652-69182653	skin	malignant_melanoma	Deletion - Frameshift
c.1516C>T; p.P506S; 2:69245306-69245306	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.957C>T; p.D319D; 2:69152174-69152174	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1269G>T; p.Q423H; 2:69182576-69182576	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.720C>T; p.V240V; 2:69102858-69102858	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.862G>T; p.E288*; 2:69123076-69123076	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.518C>T; p.A173V; 2:69075615-69075615	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1204G>T; p.G402C; 2:69182511-69182511	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1608A>C; p.P536P; 2:69245398-69245398	liver	carcinoma	Substitution - coding silent
c.1355G>A; p.G452E; 2:69193336-69193336	skin	malignant_melanoma	Substitution - Missense
c.1186-1G>T; p.?; 2:69182492-69182492	lung	carcinoma; adenocarcinoma	Unknown
c.1314T>G; p.R438R; 2:69182621-69182621	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1664C>T; p.P555L; 2:69245454-69245454	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.430G>C; p.V144L; 2:69073039-69073039	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1224T>G; p.A408A; 2:69182531-69182531	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.430G>C; p.V144L; 2:69073039-69073039	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.728G>C; p.G243A; 2:69102866-69102866	skin	malignant_melanoma	Substitution - Missense
c.584A>C; p.K195T; 2:69077430-69077430	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1312C>T; p.R438C; 2:69182619-69182619	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1312C>T; p.R438C; 2:69182619-69182619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.39C>T; p.F13F; 2:69013538-69013538	skin	malignant_melanoma	Substitution - coding silent
c.1312C>T; p.R438C; 2:69182619-69182619	stomach	adenocarcinoma	Substitution - Missense
c.1312C>T; p.R438C; 2:69182619-69182619	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.838C>T; p.L280L; 2:69123052-69123052	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.771C>T; p.C257C; 2:69102909-69102909	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.319G>C; p.E107Q; 2:69070669-69070669	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1435-5T>A; p.?; 2:69245220-69245220	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.702A>G; p.G234G; 2:69090918-69090918	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.938C>T; p.T313I; 2:69124630-69124630	large_intestine; colon	NS	Substitution - Missense
c.263G>A; p.R88Q; 2:69044780-69044780	skin	malignant_melanoma	Substitution - Missense
c.938C>T; p.T313I; 2:69124630-69124630	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.779A>C; p.K260T; 2:69102917-69102917	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1264G>A; p.E422K; 2:69182571-69182571	skin	malignant_melanoma	Substitution - Missense
c.575C>T; p.A192V; 2:69077421-69077421	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.560A>T; p.Q187L; 2:69075657-69075657	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1326C>T; p.S442S; 2:69182633-69182633	skin; upper_back	malignant_melanoma	Substitution - coding silent
c.1326C>T; p.S442S; 2:69182633-69182633	skin	malignant_melanoma	Substitution - coding silent
c.352A>C; p.T118P; 2:69070702-69070702	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.801C>T; p.L267L; 2:69102939-69102939	skin; upper_leg	malignant_melanoma	Substitution - coding silent
c.1315C>T; p.R439W; 2:69182622-69182622	skin	malignant_melanoma	Substitution - Missense
c.1601C>A; p.P534Q; 2:69245391-69245391	thyroid	other; neoplasm	Substitution - Missense
c.1325C>T; p.S442F; 2:69182632-69182632	skin	malignant_melanoma	Substitution - Missense
c.1567C>T; p.P523S; 2:69245357-69245357	skin	malignant_melanoma	Substitution - Missense
c.1325C>T; p.S442F; 2:69182632-69182632	skin	malignant_melanoma	Substitution - Missense
c.359T>C; p.M120T; 2:69070709-69070709	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1517C>T; p.P506L; 2:69245307-69245307	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1126C>T; p.P376S; 2:69181822-69181822	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1353G>T; p.K451N; 2:69182660-69182660	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1353G>T; p.K451N; 2:69182660-69182660	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1161C>T; p.G387G; 2:69181857-69181857	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1263G>A; p.P421P; 2:69182570-69182570	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.812C>G; p.P271R; 2:69123026-69123026	stomach	adenocarcinoma	Substitution - Missense
c.1390G>T; p.G464*; 2:69193371-69193371	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.308G>A; p.R103H; 2:69070658-69070658	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1497C>T; p.N499N; 2:69245287-69245287	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.766C>A; p.L256I; 2:69102904-69102904	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1061T>C; p.V354A; 2:69170261-69170261	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.722T>G; p.V241G; 2:69102860-69102860	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.996G>T; p.L332L; 2:69152213-69152213	pancreas	carcinoma	Substitution - coding silent
c.1130C>T; p.T377M; 2:69181826-69181826	breast	carcinoma	Substitution - Missense
c.72C>T; p.I24I; 2:69013571-69013571	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.848C>T; p.A283V; 2:69123062-69123062	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1400G>A; p.R467H; 2:69193381-69193381	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.491A>G; p.E164G; 2:69073100-69073100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1369T>C; p.L457L; 2:69193350-69193350	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.551A>G; p.N184S; 2:69075648-69075648	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1438C>T; p.R480C; 2:69245228-69245228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1438C>T; p.R480C; 2:69245228-69245228	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.153-1G>C; p.?; 2:69040043-69040043	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Unknown
c.153-1G>C; p.?; 2:69040043-69040043	urinary_tract; bladder	carcinoma	Unknown
c.1515G>A; p.S505S; 2:69245305-69245305	breast	carcinoma	Substitution - coding silent
c.1515G>A; p.S505S; 2:69245305-69245305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.262C>T; p.R88*; 2:69044779-69044779	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1438C>T; p.R480C; 2:69245228-69245228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1438C>T; p.R480C; 2:69245228-69245228	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.627A>G; p.Q209Q; 2:69077473-69077473	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1282C>T; p.P428S; 2:69182589-69182589	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1225A>G; p.K409E; 2:69182532-69182532	central_nervous_system; brain	glioma	Substitution - Missense
c.471C>A; p.L157L; 2:69073080-69073080	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.795C>A; p.V265V; 2:69102933-69102933	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.430G>A; p.V144I; 2:69073039-69073039	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.430G>A; p.V144I; 2:69073039-69073039	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1189C>T; p.R397C; 2:69182496-69182496	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1189C>T; p.R397C; 2:69182496-69182496	skin	malignant_melanoma	Substitution - Missense
c.1189C>T; p.R397C; 2:69182496-69182496	skin	malignant_melanoma	Substitution - Missense
c.1325delC; p.R444fs*18; 2:69182632-69182632	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1189C>T; p.R397C; 2:69182496-69182496	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1189C>T; p.R397C; 2:69182496-69182496	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1178G>T; p.R393I; 2:69181874-69181874	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1608A>T; p.P536P; 2:69245398-69245398	thyroid	other; neoplasm	Substitution - coding silent
c.689C>T; p.T230I; 2:69090905-69090905	skin	malignant_melanoma	Substitution - Missense
c.511C>T; p.L171F; 2:69075608-69075608	skin	malignant_melanoma	Substitution - Missense
c.624G>A; p.L208L; 2:69077470-69077470	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1602G>T; p.P534P; 2:69245392-69245392	thyroid	other; neoplasm	Substitution - coding silent
c.601G>A; p.V201M; 2:69077447-69077447	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.621T>C; p.A207A; 2:69077467-69077467	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1276G>A; p.E426K; 2:69182583-69182583	skin	malignant_melanoma	Substitution - Missense
c.1388A>C; p.K463T; 2:69193369-69193369	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1043C>T; p.T348I; 2:69152260-69152260	NS	malignant_melanoma	Substitution - Missense
c.1245T>C; p.N415N; 2:69182552-69182552	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1043C>T; p.T348I; 2:69152260-69152260	NS	malignant_melanoma	Substitution - Missense
c.952-8C>T; p.?; 2:69152161-69152161	skin; trunk	malignant_melanoma; nodular	Unknown
c.320A>G; p.E107G; 2:69070670-69070670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1078G>A; p.E360K; 2:69170278-69170278	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.574G>A; p.A192T; 2:69077420-69077420	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.117C>T; p.C39C; 2:69013616-69013616	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.707C>A; p.S236*; 2:69102845-69102845	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1606C>T; p.P536S; 2:69245396-69245396	thyroid	other; neoplasm	Substitution - Missense
c.721G>A; p.V241M; 2:69102859-69102859	central_nervous_system; brain	glioma	Substitution - Missense
c.1292G>A; p.R431Q; 2:69182599-69182599	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.996G>A; p.L332L; 2:69152213-69152213	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.427A>T; p.S143C; 2:69073036-69073036	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.996G>A; p.L332L; 2:69152213-69152213	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1316G>A; p.R439Q; 2:69182623-69182623	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1281C>T; p.F427F; 2:69182588-69182588	skin	malignant_melanoma	Substitution - coding silent
c.166C>T; p.L56L; 2:69040057-69040057	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.382A>T; p.S128C; 2:69071757-69071757	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.297A>G; p.R99R; 2:69070647-69070647	central_nervous_system; brain	glioma	Substitution - coding silent
c.553G>A; p.E185K; 2:69075650-69075650	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.321A>G; p.E107E; 2:69070671-69070671	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1567_1568CC>TT; p.P523F; 2:69245357-69245358	skin	malignant_melanoma	Substitution - Missense
c.1089G>A; p.E363E; 2:69170289-69170289	skin	malignant_melanoma	Substitution - coding silent
c.1553C>T; p.A518V; 2:69245343-69245343	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation