Cancer metastasis database

Annotation category 5

Gene information

Gene ID 84148
Symbol

KAT8

Synonymous

MOF|MYST1|ZC2HC8|hMOF

Full name

K(lysine) acetyltransferase 8

Gene description

MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1|MYST histone acetyltransferase 1|MYST-1|histone acetyltransferase KAT8|histone acetyltransferase MYST1|lysine acetyltransferase 8|ortholog of Drosophila males absent on the first (MOF)|probable histone acetyltransf

Cytoband

16p11.2

Gene type

protein-coding

Synonymous

MIM:609912; HGNC:HGNC:17933; Ensembl:ENSG00000103510; HPRD:11381; Vega:OTTHUMG00000132410

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.406C>T; p.R136C; 16:31120458-31120458

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1126T>C; p.F376L; 16:31130575-31130575

 thyroidcarcinomaSubstitution - Missense

c.1039G>A; p.G347S; 16:31130488-31130488

 skinmalignant_melanomaSubstitution - Missense

c.431G>A; p.R144H; 16:31120483-31120483

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.881_882insG; p.A296fs*43; 16:31130126-31130127

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1323G>A; p.G441G; 16:31130911-31130911

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.781C>T; p.Q261*; 16:31130026-31130026

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.255C>T; p.G85G; 16:31120229-31120229

 skinmalignant_melanomaSubstitution - coding silent

c.508C>G; p.H170D; 16:31127080-31127080

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.901T>C; p.Y301H; 16:31130146-31130146

 skinmalignant_melanomaSubstitution - Missense

c.844C>T; p.P282S; 16:31130089-31130089

 skinmalignant_melanomaSubstitution - Missense

c.1272G>A; p.E424E; 16:31130860-31130860

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.58G>A; p.E20K; 16:31117739-31117739

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.562G>A; p.E188K; 16:31127234-31127234

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1048G>A; p.E350K; 16:31130497-31130497

 skinmalignant_melanomaSubstitution - Missense

c.292C>T; p.R98W; 16:31120344-31120344

 skinmalignant_melanomaSubstitution - Missense

c.292C>T; p.R98W; 16:31120344-31120344

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.292C>T; p.R98W; 16:31120344-31120344

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.292C>T; p.R98W; 16:31120344-31120344

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.1265T>C; p.V422A; 16:31130853-31130853

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.390C>T; p.L130L; 16:31120442-31120442

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.766C>T; p.H256Y; 16:31128134-31128134

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1049A>C; p.E350A; 16:31130498-31130498

 pancreascarcinomaSubstitution - Missense

c.1049A>C; p.E350A; 16:31130498-31130498

 pancreascarcinomaSubstitution - Missense

c.1049A>C; p.E350A; 16:31130498-31130498

 pancreascarcinomaSubstitution - Missense

c.997A>G; p.I333V; 16:31130351-31130351

 livercarcinomaSubstitution - Missense

c.671G>A; p.R224H; 16:31127343-31127343

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.671G>A; p.R224H; 16:31127343-31127343

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.760A>G; p.K254E; 16:31128128-31128128

 pancreascarcinomaSubstitution - Missense

c.295C>T; p.R99W; 16:31120347-31120347

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.554G>A; p.G185E; 16:31127226-31127226

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1278C>T; p.L426L; 16:31130866-31130866

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1143C>T; p.S381S; 16:31130592-31130592

 skinmalignant_melanomaSubstitution - coding silent

c.419G>A; p.R140H; 16:31120471-31120471

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.419G>A; p.R140H; 16:31120471-31120471

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.419G>A; p.R140H; 16:31120471-31120471

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastomaSubstitution - Missense

c.961delC; p.Y323fs*48; 16:31130315-31130315

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.681+1G>A; p.?; 16:31127354-31127354

 livercarcinomaUnknown

c.681+1G>A; p.?; 16:31127354-31127354

 livercarcinomaUnknown

c.741C>T; p.S247S; 16:31128109-31128109

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1056A>G; p.P352P; 16:31130505-31130505

 thyroidother; neoplasmSubstitution - coding silent

c.168G>C; p.E56D; 16:31117849-31117849

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.879G>A; p.R293R; 16:31130124-31130124

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.430C>T; p.R144C; 16:31120482-31120482

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.612G>T; p.Q204H; 16:31127284-31127284

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.749A>G; p.E250G; 16:31128117-31128117

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense