lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	818
Symbol	CAMK2G
Synonymous	CAMK\|CAMK-II\|CAMKG
Full name	calcium/calmodulin-dependent protein kinase II gamma
Gene description	caMK-II subunit gamma\|calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma\|calcium/calmodulin-dependent protein kinase type II subunit gamma
Cytoband	10q22
Gene type	protein-coding
Synonymous	MIM:602123; HGNC:HGNC:1463; Ensembl:ENSG00000148660; HPRD:03672; Vega:OTTHUMG00000018492

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.637_638CC>TT; p.P213F; 10:73848046-73848047	skin	malignant_melanoma	Substitution - Missense
c.637_638CC>TT; p.P213F; 10:73848046-73848047	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.147G>C; p.K49N; 10:73873002-73873002	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.712T>C; p.W238R; 10:73847332-73847332	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1470_1471insC; p.A491fs*>6; 10:73815032-73815033	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Insertion - Frameshift
c.1047G>C; p.E349D; 10:73821719-73821719	liver	carcinoma	Substitution - Missense
c.225C>T; p.R75R; 10:73853242-73853242	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.991G>T; p.E331*; 10:73824084-73824084	liver	carcinoma	Substitution - Nonsense
c.1440C>G; p.L480L; 10:73815063-73815063	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.403A>G; p.R135G; 10:73849272-73849272	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.532C>A; p.P178T; 10:73848595-73848595	breast	carcinoma	Substitution - Missense
c.246A>G; p.E82E; 10:73853221-73853221	breast	carcinoma	Substitution - coding silent
c.918G>T; p.T306T; 10:73842197-73842197	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.364G>A; p.E122K; 10:73849311-73849311	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.364G>A; p.E122K; 10:73849311-73849311	urinary_tract; bladder	carcinoma	Substitution - Missense
c.401A>G; p.H134R; 10:73849274-73849274	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.220G>A; p.V74M; 10:73860830-73860830	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1020T>C; p.A340A; 10:73824055-73824055	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1353C>T; p.L451L; 10:73815150-73815150	skin	malignant_melanoma	Substitution - coding silent
c.290A>G; p.E97G; 10:73852305-73852305	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1088G>A; p.R363Q; 10:73817551-73817551	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.275+2T>C; p.?; 10:73853190-73853190	stomach	carcinoma; adenocarcinoma	Unknown
c.187C>A; p.R63R; 10:73860863-73860863	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1024G>T; p.D342Y; 10:73824051-73824051	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1331C>T; p.A444V; 10:73815172-73815172	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1327G>A; p.A443T; 10:73815176-73815176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1316T>C; p.I439T; 10:73815187-73815187	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.284G>A; p.G95D; 10:73852311-73852311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.396C>T; p.I132I; 10:73849279-73849279	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.396C>T; p.I132I; 10:73849279-73849279	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.882C>G; p.F294L; 10:73842479-73842479	urinary_tract; bladder	carcinoma	Substitution - Missense
c.751C>T; p.Q251*; 10:73847293-73847293	skin	malignant_melanoma	Substitution - Nonsense
c.1370G>A; p.G457E; 10:73815133-73815133	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1349G>A; p.R450H; 10:73815154-73815154	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1434G>A; p.K478K; 10:73815069-73815069	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.809C>A; p.P270Q; 10:73847235-73847235	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.727C>T; p.P243S; 10:73847317-73847317	skin; scalp	malignant_melanoma	Substitution - Missense
c.191T>C; p.I64T; 10:73860859-73860859	breast	carcinoma	Substitution - Missense
c.1312G>A; p.V438M; 10:73815191-73815191	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.568C>T; p.P190S; 10:73848559-73848559	skin	malignant_melanoma	Substitution - Missense
c.144G>T; p.K48N; 10:73873005-73873005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1165A>G; p.I389V; 10:73817113-73817113	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.618C>T; p.I206I; 10:73848066-73848066	skin	malignant_melanoma	Substitution - coding silent
c.638C>T; p.P213L; 10:73848046-73848046	skin	malignant_melanoma	Substitution - Missense
c.1328C>T; p.A443V; 10:73815175-73815175	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.147G>A; p.K49K; 10:73873002-73873002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.147G>A; p.K49K; 10:73873002-73873002	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.147G>A; p.K49K; 10:73873002-73873002	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.147G>A; p.K49K; 10:73873002-73873002	kidney	other; neoplasm	Substitution - coding silent
c.536G>T; p.G179V; 10:73848591-73848591	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.343C>A; p.H115N; 10:73849332-73849332	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.787G>A; p.A263T; 10:73847257-73847257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.713G>A; p.W238*; 10:73847331-73847331	stomach	carcinoma	Substitution - Nonsense
c.719C>T; p.T240M; 10:73847325-73847325	pancreas	carcinoma	Substitution - Missense
c.719C>T; p.T240M; 10:73847325-73847325	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1330G>A; p.A444T; 10:73815173-73815173	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1160+1G>A; p.?; 10:73817478-73817478	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.701C>T; p.P234L; 10:73847343-73847343	skin	malignant_melanoma	Substitution - Missense
c.545C>T; p.S182F; 10:73848582-73848582	skin	malignant_melanoma	Substitution - Missense
c.813G>A; p.W271*; 10:73847231-73847231	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.251G>C; p.G84A; 10:73853216-73853216	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.486C>T; p.I162I; 10:73849044-73849044	skin	malignant_melanoma	Substitution - coding silent
c.610C>T; p.L204L; 10:73848074-73848074	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1210A>T; p.N404Y; 10:73817068-73817068	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.221-1G>A; p.?; 10:73853247-73853247	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.48C>T; p.L16L; 10:73874414-73874414	skin	malignant_melanoma	Substitution - coding silent
c.1036-2A>T; p.?; 10:73821732-73821732	lung	carcinoma; adenocarcinoma	Unknown
c.66-1G>T; p.?; 10:73873084-73873084	lung	carcinoma; non_small_cell_carcinoma	Unknown
c.66-1G>T; p.?; 10:73873084-73873084	lung	carcinoma; non_small_cell_carcinoma	Unknown
c.141C>G; p.T47T; 10:73873008-73873008	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.738G>T; p.K246N; 10:73847306-73847306	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1460C>T; p.S487L; 10:73815043-73815043	urinary_tract; bladder	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation