Cancer metastasis database

Annotation category 5

Gene information

Gene ID 80380
Symbol

PDCD1LG2

Synonymous

B7DC|Btdc|CD273|PD-L2|PDCD1L2|PDL2|bA574F11.2

Full name

programmed cell death 1 ligand 2

Gene description

B7 dendritic cell molecule|B7-DC|PD-1 ligand 2|PD-1-ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|programmed death ligand 2

Cytoband

9p24.2

Gene type

protein-coding

Synonymous

MIM:605723; HGNC:HGNC:18731; Ensembl:ENSG00000197646; HPRD:16147; Vega:OTTHUMG00000019504

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.601G>A; p.E201K; 9:5549574-5549574

 skinmalignant_melanomaSubstitution - Missense

c.306C>T; p.C102C; 9:5534995-5534995

 prostatecarcinomaSubstitution - coding silent

c.486C>T; p.A162A; 9:5549459-5549459

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.731G>A; p.R244K; 9:5557717-5557717

 skinmalignant_melanomaSubstitution - Missense

c.542G>A; p.R181H; 9:5549515-5549515

 prostatecarcinomaSubstitution - Missense

c.768C>T; p.D256D; 9:5563163-5563163

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.232G>A; p.E78K; 9:5534921-5534921

 skinmalignant_melanomaSubstitution - Missense

c.242_243CC>TT; p.P81L; 9:5534931-5534932

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.654T>A; p.H218Q; 9:5557640-5557640

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.500C>T; p.S167F; 9:5549473-5549473

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.758C>G; p.S253C; 9:5557744-5557744

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.289G>A; p.E97K; 9:5534978-5534978

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.193G>C; p.D65H; 9:5534882-5534882

 ovaryother; neoplasmSubstitution - Missense

c.95T>C; p.I32T; 9:5534784-5534784

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.538C>T; p.L180L; 9:5549511-5549511

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.294A>G; p.G98G; 9:5534983-5534983

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.553delC; p.P186fs*14; 9:5549526-5549526

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.553delC; p.P186fs*14; 9:5549526-5549526

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.761C>T; p.S254L; 9:5557747-5557747

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.325G>A; p.A109T; 9:5535014-5535014

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.65C>A; p.T22K; 9:5534754-5534754

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.722T>C; p.I241T; 9:5557708-5557708

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.75C>A; p.V25V; 9:5534764-5534764

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.209G>A; p.R70H; 9:5534898-5534898

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.197C>A; p.T66K; 9:5534886-5534886

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.785T>A; p.V262D; 9:5563180-5563180

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.785T>A; p.V262D; 9:5563180-5563180

 large_intestine; coloncarcinomaSubstitution - Missense

c.577G>A; p.V193M; 9:5549550-5549550

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.220A>G; p.T74A; 9:5534909-5534909

 thyroidcarcinomaSubstitution - Missense

c.490A>C; p.T164P; 9:5549463-5549463

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.12C>T; p.L4L; 9:5522558-5522558

 oesophaguscarcinomaSubstitution - coding silent

c.643C>T; p.P215S; 9:5557629-5557629

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.18A>C; p.L6L; 9:5522564-5522564

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.506C>A; p.T169N; 9:5549479-5549479

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.480T>C; p.V160V; 9:5549453-5549453

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent