Cancer metastasis database

Annotation category 5

Gene information

Gene ID 79679
Symbol

VTCN1

Synonymous

B7-H4|B7H4|B7S1|B7X|B7h.5|PRO1291|VCTN1

Full name

V-set domain containing T cell activation inhibitor 1

Gene description

B7 family member, H4|B7 homolog 4|B7 superfamily member 1|T cell costimulatory molecule B7x|T-cell costimulatory molecule B7x|V-set domain-containing T-cell activation inhibitor 1|immune costimulatory protein B7-H4

Cytoband

1p13.1

Gene type

protein-coding

Synonymous

MIM:608162; HGNC:HGNC:28873; Ensembl:ENSG00000134258; HPRD:06429; Vega:OTTHUMG00000012118

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.175G>A; p.E59K; 1:117156844-117156844

 skinmalignant_melanomaSubstitution - Missense

c.126C>T; p.V42V; 1:117156893-117156893

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.749A>C; p.H250P; 1:117147758-117147758

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.573C>A; p.F191L; 1:117153242-117153242

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.728C>T; p.S243L; 1:117147779-117147779

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.728C>T; p.S243L; 1:117147779-117147779

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.545C>T; p.A182V; 1:117153270-117153270

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.654G>A; p.T218T; 1:117153161-117153161

 skinmalignant_melanomaSubstitution - coding silent

c.370G>T; p.D124Y; 1:117156649-117156649

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.370G>T; p.D124Y; 1:117156649-117156649

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.108C>T; p.S36S; 1:117156911-117156911

 skinmalignant_melanomaSubstitution - coding silent

c.73C>T; p.L25F; 1:117170131-117170131

 skinmalignant_melanomaSubstitution - Missense

c.273G>T; p.S91S; 1:117156746-117156746

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.490G>A; p.E164K; 1:117153325-117153325

 breastcarcinomaSubstitution - Missense

c.268C>T; p.L90L; 1:117156751-117156751

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.795_798delCTTT; p.F265fs*14; 1:117147709-117147712

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.825C>A; p.L275L; 1:117147682-117147682

 breastcarcinomaSubstitution - coding silent

c.134C>A; p.A45D; 1:117156885-117156885

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.80T>A; p.I27N; 1:117170124-117170124

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.176A>G; p.E59G; 1:117156843-117156843

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.299G>A; p.R100Q; 1:117156720-117156720

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.804C>T; p.I268I; 1:117147703-117147703

 parathyroidcarcinomaSubstitution - coding silent

c.421G>A; p.A141T; 1:117156598-117156598

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.245A>C; p.E82A; 1:117156774-117156774

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.346C>T; p.R116W; 1:117156673-117156673

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.346C>T; p.R116W; 1:117156673-117156673

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.194C>G; p.S65C; 1:117156825-117156825

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.194C>G; p.S65C; 1:117156825-117156825

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.194C>G; p.S65C; 1:117156825-117156825

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.682G>A; p.E228K; 1:117153133-117153133

 skinmalignant_melanomaSubstitution - Missense

c.307G>A; p.V103M; 1:117156712-117156712

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.307G>A; p.V103M; 1:117156712-117156712

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.295G>T; p.G99C; 1:117156724-117156724

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.297C>T; p.G99G; 1:117156722-117156722

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.298C>A; p.R100R; 1:117156721-117156721

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.378C>T; p.G126G; 1:117156641-117156641

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.708G>A; p.G236G; 1:117153107-117153107

 skinmalignant_melanomaSubstitution - coding silent

c.249C>T; p.F83F; 1:117156770-117156770

 skinmalignant_melanomaSubstitution - coding silent

c.499C>A; p.R167R; 1:117153316-117153316

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.358G>A; p.V120M; 1:117156661-117156661

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.385A>G; p.K129E; 1:117156634-117156634

 livercarcinomaSubstitution - Missense

c.385A>G; p.K129E; 1:117156634-117156634

 livercarcinomaSubstitution - Missense

c.465G>A; p.V155V; 1:117153350-117153350

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.575C>T; p.S192L; 1:117153240-117153240

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.143T>C; p.I48T; 1:117156876-117156876

 livercarcinomaSubstitution - Missense

c.5C>T; p.A2V; 1:117210851-117210851

 skinmalignant_melanomaSubstitution - Missense

c.5C>T; p.A2V; 1:117210851-117210851

 skinmalignant_melanomaSubstitution - Missense

c.332G>A; p.G111D; 1:117156687-117156687

 breastcarcinomaSubstitution - Missense

c.219G>A; p.K73K; 1:117156800-117156800

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.688G>A; p.D230N; 1:117153127-117153127

 skinmalignant_melanomaSubstitution - Missense

c.767C>T; p.S256L; 1:117147740-117147740

 skinmalignant_melanomaSubstitution - Missense

c.8C>T; p.S3F; 1:117210848-117210848

 skinmalignant_melanomaSubstitution - Missense

c.316G>A; p.D106N; 1:117156703-117156703

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense