lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	79444
Symbol	BIRC7
Synonymous	KIAP\|LIVIN\|ML-IAP\|MLIAP\|RNF50
Full name	baculoviral IAP repeat containing 7
Gene description	RING finger protein 50\|baculoviral IAP repeat-containing protein 7\|kidney inhibitor of apoptosis protein\|livin inhibitor of apoptosis\|melanoma inhibitor of apoptosis protein
Cytoband	20q13.3
Gene type	protein-coding
Synonymous	MIM:605737; HGNC:HGNC:13702; Ensembl:ENSG00000101197; HPRD:05761; Vega:OTTHUMG00000032957

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.697delC; p.P234fs*>65; 20:63239405-63239405	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.207G>T; p.E69D; 20:63236303-63236303	breast	carcinoma	Substitution - Missense
c.180G>A; p.R60R; 20:63236276-63236276	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.171C>G; p.G57G; 20:63236267-63236267	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.180G>A; p.R60R; 20:63236276-63236276	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.797C>T; p.P266L; 20:63239505-63239505	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.349G>T; p.G117C; 20:63236445-63236445	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.526T>G; p.S176A; 20:63238472-63238472	skin	malignant_melanoma	Substitution - Missense
c.190G>C; p.E64Q; 20:63236286-63236286	breast	carcinoma	Substitution - Missense
c.491A>G; p.H164R; 20:63238437-63238437	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.491A>G; p.H164R; 20:63238437-63238437	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.409G>A; p.G137R; 20:63237962-63237962	breast	carcinoma	Substitution - Missense
c.787G>A; p.V263I; 20:63239495-63239495	pancreas	carcinoma	Substitution - Missense
c.264G>A; p.E88E; 20:63236360-63236360	pancreas	carcinoma	Substitution - coding silent
c.169G>T; p.G57C; 20:63236265-63236265	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.852C>T; p.I284I; 20:63239560-63239560	skin	malignant_melanoma	Substitution - coding silent
c.202G>A; p.E68K; 20:63236298-63236298	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.759G>T; p.K253N; 20:63239467-63239467	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.561C>A; p.A187A; 20:63238598-63238598	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.528C>T; p.S176S; 20:63238474-63238474	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.528C>T; p.S176S; 20:63238474-63238474	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.528C>T; p.S176S; 20:63238474-63238474	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.418C>T; p.P140S; 20:63237971-63237971	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.386G>A; p.G129E; 20:63237939-63237939	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.681G>T; p.A227A; 20:63239389-63239389	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.843G>T; p.L281L; 20:63239551-63239551	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.111C>T; p.S37S; 20:63236207-63236207	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.827C>T; p.A276V; 20:63239535-63239535	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.408C>T; p.R136R; 20:63237961-63237961	pancreas	carcinoma	Substitution - coding silent
c.881G>A; p.R294H; 20:63239589-63239589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.881G>A; p.R294H; 20:63239589-63239589	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.306G>C; p.E102D; 20:63236402-63236402	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.768G>A; p.L256L; 20:63239476-63239476	skin	malignant_melanoma	Substitution - coding silent
c.143G>A; p.W48*; 20:63236239-63236239	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.511T>A; p.S171T; 20:63238457-63238457	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.772C>T; p.R258C; 20:63239480-63239480	lung	carcinoma; undifferentiated_carcinoma	Substitution - Missense
c.211G>A; p.A71T; 20:63236307-63236307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.411G>T; p.G137G; 20:63237964-63237964	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.667G>C; p.E223Q; 20:63239375-63239375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.667G>C; p.E223Q; 20:63239375-63239375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.667G>C; p.E223Q; 20:63239375-63239375	breast	carcinoma	Substitution - Missense
c.77C>G; p.T26R; 20:63236173-63236173	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.551A>G; p.E184G; 20:63238588-63238588	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.840G>A; p.Q280Q; 20:63239548-63239548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.304G>C; p.E102Q; 20:63236400-63236400	ovary	other; neoplasm	Substitution - Missense
c.868C>T; p.R290C; 20:63239576-63239576	skin	malignant_melanoma	Substitution - Missense
c.865G>A; p.V289I; 20:63239573-63239573	ovary	other; neoplasm	Substitution - Missense
c.875G>C; p.R292P; 20:63239583-63239583	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.224T>C; p.L75S; 20:63236320-63236320	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.680C>T; p.A227V; 20:63239388-63239388	liver	carcinoma	Substitution - Missense
c.730C>T; p.R244W; 20:63239438-63239438	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.468G>T; p.R156R; 20:63238414-63238414	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.407G>A; p.R136H; 20:63237960-63237960	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.415G>A; p.D139N; 20:63237968-63237968	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.894C>T; p.S298S; 20:63239602-63239602	skin	malignant_melanoma	Substitution - coding silent
c.384T>C; p.Y128Y; 20:63237937-63237937	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.796C>T; p.P266S; 20:63239504-63239504	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.796C>T; p.P266S; 20:63239504-63239504	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.877G>A; p.V293M; 20:63239585-63239585	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.85C>T; p.R29C; 20:63236181-63236181	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.92G>A; p.G31E; 20:63236188-63236188	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.675G>T; p.Q225H; 20:63239383-63239383	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.820G>A; p.E274K; 20:63239528-63239528	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation