lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	79137
Symbol	FAM134A
Synonymous	C2orf17
Full name	family with sequence similarity 134, member A
Gene description	protein FAM134A
Cytoband	2q35
Gene type	protein-coding
Synonymous	HGNC:HGNC:28450; Ensembl:ENSG00000144567; HPRD:12807; Vega:OTTHUMG00000154577

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.849C>T; p.S283S; 2:219181433-219181433	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.849C>T; p.S283S; 2:219181433-219181433	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.24T>G; p.G8G; 2:219178376-219178376	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.404A>G; p.E135G; 2:219179748-219179748	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.613C>T; p.P205S; 2:219180727-219180727	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.711G>T; p.E237D; 2:219181132-219181132	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1249_1250insC; p.D420fs*40; 2:219182246-219182247	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.556T>A; p.F186I; 2:219180670-219180670	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1358T>C; p.L453P; 2:219182355-219182355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1358T>C; p.L453P; 2:219182355-219182355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1358T>C; p.L453P; 2:219182355-219182355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.763C>T; p.H255Y; 2:219181184-219181184	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1384C>T; p.P462S; 2:219182381-219182381	skin	malignant_melanoma	Substitution - Missense
c.1414C>T; p.Q472*; 2:219182411-219182411	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.967T>A; p.F323I; 2:219181727-219181727	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.808C>T; p.P270S; 2:219181392-219181392	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.887T>C; p.V296A; 2:219181647-219181647	prostate	carcinoma	Substitution - Missense
c.1450G>C; p.E484Q; 2:219182447-219182447	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.428C>T; p.A143V; 2:219180118-219180118	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1357C>T; p.L453F; 2:219182354-219182354	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1440C>T; p.A480A; 2:219182437-219182437	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.955G>C; p.E319Q; 2:219181715-219181715	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.955G>C; p.E319Q; 2:219181715-219181715	urinary_tract; bladder	carcinoma	Substitution - Missense
c.290C>T; p.S97F; 2:219178930-219178930	skin	malignant_melanoma	Substitution - Missense
c.1485G>C; p.L495L; 2:219182482-219182482	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1256C>A; p.P419Q; 2:219182253-219182253	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1395C>T; p.S465S; 2:219182392-219182392	skin	malignant_melanoma	Substitution - coding silent
c.803C>T; p.A268V; 2:219181387-219181387	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.75T>C; p.G25G; 2:219178427-219178427	thyroid	other; neoplasm	Substitution - coding silent
c.157G>T; p.A53S; 2:219178509-219178509	thyroid	other; neoplasm	Substitution - Missense
c.1553C>T; p.P518L; 2:219182550-219182550	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1322G>A; p.G441D; 2:219182319-219182319	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1601A>G; p.D534G; 2:219182598-219182598	skin	malignant_melanoma	Substitution - Missense
c.1325T>C; p.L442P; 2:219182322-219182322	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.443G>A; p.R148Q; 2:219180133-219180133	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.422A>G; p.E141G; 2:219180112-219180112	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1154C>T; p.S385L; 2:219182151-219182151	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.429_430GG>AA; p.G144R; 2:219180119-219180120	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.498C>T; p.L166L; 2:219180188-219180188	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.498C>T; p.L166L; 2:219180188-219180188	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1413C>T; p.P471P; 2:219182410-219182410	skin	malignant_melanoma	Substitution - coding silent
c.565C>T; p.R189*; 2:219180679-219180679	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.421G>T; p.E141*; 2:219180111-219180111	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.969C>T; p.F323F; 2:219181729-219181729	pancreas	carcinoma	Substitution - coding silent
c.780G>A; p.K260K; 2:219181201-219181201	breast	carcinoma	Substitution - coding silent
c.503T>A; p.F168Y; 2:219180193-219180193	salivary_gland; parotid	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.1542G>A; p.P514P; 2:219182539-219182539	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1390C>T; p.P464S; 2:219182387-219182387	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.951C>T; p.I317I; 2:219181711-219181711	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.951C>T; p.I317I; 2:219181711-219181711	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1271G>A; p.C424Y; 2:219182268-219182268	skin	malignant_melanoma	Substitution - Missense
c.1356A>C; p.P452P; 2:219182353-219182353	breast	carcinoma	Substitution - coding silent
c.1359T>C; p.L453L; 2:219182356-219182356	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1288delG; p.V430fs*4; 2:219182285-219182285	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1412C>T; p.P471L; 2:219182409-219182409	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1462A>G; p.T488A; 2:219182459-219182459	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.622A>G; p.M208V; 2:219180736-219180736	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1614G>T; p.Q538H; 2:219182611-219182611	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1339G>A; p.G447S; 2:219182336-219182336	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1339G>A; p.G447S; 2:219182336-219182336	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.664C>T; p.L222L; 2:219181085-219181085	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.296C>G; p.S99W; 2:219178936-219178936	urinary_tract; bladder	carcinoma	Substitution - Missense
c.296C>G; p.S99W; 2:219178936-219178936	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.578G>A; p.G193D; 2:219180692-219180692	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.578G>A; p.G193D; 2:219180692-219180692	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.458G>A; p.S153N; 2:219180148-219180148	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.795G>A; p.G265G; 2:219181379-219181379	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.929T>G; p.L310R; 2:219181689-219181689	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.398C>T; p.P133L; 2:219179742-219179742	skin	malignant_melanoma	Substitution - Missense
c.1135T>C; p.S379P; 2:219182132-219182132	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.423G>C; p.E141D; 2:219180113-219180113	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1424C>T; p.P475L; 2:219182421-219182421	prostate	carcinoma	Substitution - Missense
c.1003G>A; p.D335N; 2:219181763-219181763	urinary_tract; bladder	carcinoma	Substitution - Missense
c.659G>T; p.W220L; 2:219181080-219181080	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1324C>G; p.L442V; 2:219182321-219182321	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1390C>A; p.P464T; 2:219182387-219182387	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.566G>A; p.R189Q; 2:219180680-219180680	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.425G>A; p.G142D; 2:219180115-219180115	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1230G>A; p.T410T; 2:219182227-219182227	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1411C>T; p.P471S; 2:219182408-219182408	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation