Cancer metastasis database

Annotation category 5

Gene information

Gene ID 79017
Symbol

GGCT

Synonymous

C7orf24|CRF21|GCTG|GGC

Full name

gamma-glutamylcyclotransferase

Gene description

cytochrome c-releasing factor 21|gamma -glutamyl cyclotransferase

Cytoband

7p15-p14

Gene type

protein-coding

Synonymous

MIM:137170; HGNC:HGNC:21705; Ensembl:ENSG00000006625; HPRD:12912; Vega:OTTHUMG00000128593

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.114G>C; p.A38A; 7:30504596-30504596

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.175A>G; p.K59E; 7:30500648-30500648

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.523G>A; p.E175K; 7:30497136-30497136

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.367C>G; p.R123G; 7:30498859-30498859

 livercarcinomaSubstitution - Missense

c.367C>G; p.R123G; 7:30498859-30498859

 livercarcinomaSubstitution - Missense

c.367C>G; p.R123G; 7:30498859-30498859

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.308G>A; p.G103E; 7:30498918-30498918

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.435G>A; p.M145I; 7:30497224-30497224

 ovaryother; neoplasmSubstitution - Missense

c.162C>T; p.G54G; 7:30500661-30500661

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.67G>T; p.G23C; 7:30504643-30504643

 breastcarcinomaSubstitution - Missense

c.390C>T; p.Y130Y; 7:30498836-30498836

 central_nervous_system; braingliomaSubstitution - coding silent

c.215T>C; p.F72S; 7:30500608-30500608

 pancreaspancreatic_intraepithelial_neoplasia_(PanIN)Substitution - Missense

c.547G>A; p.G183R; 7:30497112-30497112

 pancreascarcinomaSubstitution - Missense

c.145T>G; p.F49V; 7:30500678-30500678

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.288-3C>T; p.?; 7:30498941-30498941

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.408C>T; p.S136S; 7:30498818-30498818

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.400C>T; p.P134S; 7:30498826-30498826

 skinmalignant_melanomaSubstitution - Missense

c.141+1G>A; p.?; 7:30504568-30504568

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.224C>A; p.P75H; 7:30500599-30500599

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.474G>T; p.E158D; 7:30497185-30497185

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.343C>G; p.Q115E; 7:30498883-30498883

 thyroidother; neoplasmSubstitution - Missense

c.334G>C; p.V112L; 7:30498892-30498892

 livercarcinomaSubstitution - Missense

c.338C>A; p.A113E; 7:30498888-30498888

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.278C>A; p.S93Y; 7:30500545-30500545

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.278C>A; p.S93Y; 7:30500545-30500545

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.278C>A; p.S93Y; 7:30500545-30500545

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.390C>G; p.Y130*; 7:30498836-30498836

 breastcarcinomaSubstitution - Nonsense

c.390C>G; p.Y130*; 7:30498836-30498836

 endometriumcarcinoma; serous_carcinomaSubstitution - Nonsense

c.229G>A; p.D77N; 7:30500594-30500594

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.140A>G; p.Q47R; 7:30504570-30504570

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.403C>A; p.P135T; 7:30498823-30498823

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.11C>A; p.S4*; 7:30504699-30504699

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.407C>T; p.S136F; 7:30498819-30498819

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.308G>C; p.G103A; 7:30498918-30498918

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense