Cancer metastasis database

Annotation category 5

Gene information

Gene ID 7517
Symbol

XRCC3

Synonymous

CMM6

Full name

X-ray repair complementing defective repair in Chinese hamster cells 3

Gene description

DNA repair protein XRCC3|X-ray repair cross-complementing protein 3

Cytoband

14q32.3

Gene type

protein-coding

Synonymous

MIM:600675; HGNC:HGNC:12830; Ensembl:ENSG00000126215; HPRD:07201; Vega:OTTHUMG00000169228

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.761T>C; p.L254P; 14:103699377-103699377

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.123C>T; p.L41L; 14:103708592-103708592

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.567C>A; p.T189T; 14:103699571-103699571

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.228_229insC; p.T77fs*28; 14:103707180-103707181

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.889C>T; p.L297L; 14:103698950-103698950

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.768C>T; p.I256I; 14:103699370-103699370

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.903C>A; p.L301L; 14:103698936-103698936

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.900G>A; p.R300R; 14:103698939-103698939

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.548A>C; p.H183P; 14:103703186-103703186

 livercarcinomaSubstitution - Missense

c.485G>A; p.R162H; 14:103703249-103703249

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.36T>G; p.I12M; 14:103711052-103711052

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.153A>G; p.R51R; 14:103708562-103708562

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.205C>A; p.H69N; 14:103707204-103707204

 livercarcinomaSubstitution - Missense

c.666A>G; p.E222E; 14:103699472-103699472

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.666A>G; p.E222E; 14:103699472-103699472

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1013G>A; p.R338Q; 14:103698826-103698826

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1013G>A; p.R338Q; 14:103698826-103698826

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.722C>T; p.T241M; 14:103699416-103699416

 thyroidother; neoplasmSubstitution - Missense

c.722C>T; p.T241M; 14:103699416-103699416

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.722C>T; p.T241M; 14:103699416-103699416

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.822-2A>G; p.?; 14:103699019-103699019

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; follicular_lymphomaUnknown

c.133G>A; p.E45K; 14:103708582-103708582

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.186C>T; p.I62I; 14:103708529-103708529

 skinmalignant_melanomaSubstitution - coding silent

c.684C>T; p.S228S; 14:103699454-103699454

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.965A>C; p.H322P; 14:103698874-103698874

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.611G>A; p.R204Q; 14:103699527-103699527

 ovaryother; neoplasmSubstitution - Missense

c.295C>T; p.L99L; 14:103707114-103707114

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.68C>T; p.S23L; 14:103708647-103708647

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.68C>T; p.S23L; 14:103708647-103708647

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.975delC; p.S326fs*>21; 14:103698864-103698864

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.975delC; p.S326fs*>21; 14:103698864-103698864

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.81T>G; p.V27V; 14:103708634-103708634

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.132C>T; p.P44P; 14:103708583-103708583

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.685G>A; p.A229T; 14:103699453-103699453

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.816G>T; p.P272P; 14:103699138-103699138

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.774+2T>C; p.?; 14:103699362-103699362

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.352C>T; p.L118L; 14:103707057-103707057

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.322C>T; p.R108C; 14:103707087-103707087

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.924C>T; p.L308L; 14:103698915-103698915

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.924C>T; p.L308L; 14:103698915-103698915

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.975_976insC; p.S326fs*>22; 14:103698863-103698864

 large_intestine; rectumcarcinoma; adenocarcinomaInsertion - Frameshift

c.113T>C; p.L38P; 14:103708602-103708602

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1018A>T; p.T340S; 14:103698821-103698821

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.543C>T; p.I181I; 14:103703191-103703191

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent