lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	7423
Symbol	VEGFB
Synonymous	VEGFL\|VRF
Full name	vascular endothelial growth factor B
Gene description	VEGF-related factor
Cytoband	11q13
Gene type	protein-coding
Synonymous	MIM:601398; HGNC:HGNC:12681; HPRD:03237

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.405A>G; p.P135P; 11:64237217-64237217	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.408C>T; p.D136D; 11:64237220-64237220	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.457T>A; p.W153R; 11:64237466-64237466	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.195C>T; p.A65A; 11:64235904-64235904	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.498C>A; p.T166T; 11:64237507-64237507	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.498C>A; p.T166T; 11:64237507-64237507	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.375-5T>G; p.?; 11:64237182-64237182	prostate	carcinoma	Unknown
c.105G>A; p.V35V; 11:64235814-64235814	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.380A>C; p.K127T; 11:64237192-64237192	liver	carcinoma	Substitution - Missense
c.380A>C; p.K127T; 11:64237192-64237192	liver	carcinoma	Substitution - Missense
c.380A>C; p.K127T; 11:64237192-64237192	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.89G>A; p.G30D; 11:64235486-64235486	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.352G>T; p.E118*; 11:64236305-64236305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.382A>C; p.K128Q; 11:64237194-64237194	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.567A>C; p.G189G; 11:64237576-64237576	skin	malignant_melanoma	Substitution - coding silent
c.401A>C; p.K134T; 11:64237213-64237213	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.455G>A; p.G152D; 11:64237464-64237464	urinary_tract; bladder	carcinoma	Substitution - Missense
c.132C>T; p.R44R; 11:64235841-64235841	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.508C>T; p.P170S; 11:64237517-64237517	skin	malignant_melanoma	Substitution - Missense
c.503C>T; p.P168L; 11:64237512-64237512	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.307A>C; p.M103L; 11:64236260-64236260	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.502C>T; p.P168S; 11:64237511-64237511	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.216C>T; p.C72C; 11:64235925-64235925	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.79G>A; p.D27N; 11:64235476-64235476	urinary_tract; bladder	carcinoma	Substitution - Missense
c.383A>G; p.K128R; 11:64237195-64237195	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.217G>A; p.V73M; 11:64235926-64235926	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.407A>C; p.D136A; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.407A>T; p.D136V; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.407A>T; p.D136V; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.407A>T; p.D136V; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.407A>T; p.D136V; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.407A>T; p.D136V; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.407A>G; p.D136G; 11:64237219-64237219	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.384A>C; p.K128N; 11:64237196-64237196	liver	carcinoma	Substitution - Missense
c.384A>C; p.K128N; 11:64237196-64237196	liver	carcinoma	Substitution - Missense
c.446C>T; p.S149F; 11:64237455-64237455	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.379_380delAA; p.K129fs*35; 11:64237191-64237192	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.559A>C; p.T187P; 11:64237568-64237568	central_nervous_system; brain	glioma	Substitution - Missense
c.559A>C; p.T187P; 11:64237568-64237568	central_nervous_system; brain	glioma	Substitution - Missense
c.375-6T>G; p.?; 11:64237181-64237181	stomach	adenocarcinoma	Unknown
c.559A>C; p.T187P; 11:64237568-64237568	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.559A>C; p.T187P; 11:64237568-64237568	skin	malignant_melanoma	Substitution - Missense
c.148C>T; p.R50W; 11:64235857-64235857	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.379delA; p.K129fs*5; 11:64237191-64237191	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.471C>T; p.P157P; 11:64237480-64237480	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation