lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	7329
Symbol	UBE2I
Synonymous	C358B7.1\|P18\|UBC9
Full name	ubiquitin-conjugating enzyme E2I
Gene description	SUMO-1-protein ligase\|SUMO-conjugating enzyme UBC9\|SUMO-protein ligase\|ubiquitin carrier protein 9\|ubiquitin carrier protein I\|ubiquitin conjugating enzyme 9\|ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)\|ubiquitin-conjugating enzyme E2I (homologo
Cytoband	16p13.3
Gene type	protein-coding
Synonymous	MIM:601661; HGNC:HGNC:12485; Ensembl:ENSG00000103275; HPRD:09045; Vega:OTTHUMG00000186701

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.13G>A; p.A5T; 16:1314043-1314043	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.368C>T; p.P123L; 16:1320472-1320472	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.262C>T; p.P88S; 16:1320212-1320212	skin	malignant_melanoma	Substitution - Missense
c.111C>T; p.N37N; 16:1314337-1314337	skin	malignant_melanoma	Substitution - coding silent
c.111C>T; p.N37N; 16:1314337-1314337	skin	malignant_melanoma	Substitution - coding silent
c.111C>T; p.N37N; 16:1314337-1314337	skin	malignant_melanoma	Substitution - coding silent
c.110A>G; p.N37S; 16:1314336-1314336	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.311G>T; p.R104M; 16:1320261-1320261	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.247C>A; p.H83N; 16:1320197-1320197	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>T; p.Y87Y; 16:1320211-1320211	skin	malignant_melanoma	Substitution - coding silent
c.266C>T; p.S89L; 16:1320216-1320216	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.109A>G; p.N37D; 16:1314335-1314335	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.129C>T; p.C43C; 16:1314355-1314355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.137C>T; p.P46L; 16:1314363-1314363	skin	malignant_melanoma	Substitution - Missense
c.90A>G; p.K30K; 16:1314316-1314316	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.334-1G>C; p.?; 16:1320437-1320437	breast	carcinoma; ductal_carcinoma	Unknown
c.247C>T; p.H83Y; 16:1320197-1320197	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.139G>A; p.G47R; 16:1314365-1314365	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.138A>G; p.P46P; 16:1314364-1314364	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.203A>T; p.Y68F; 16:1315706-1315706	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.231C>T; p.F77F; 16:1320181-1320181	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.348A>G; p.I116M; 16:1320452-1320452	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.211T>C; p.S71P; 16:1315714-1315714	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.428A>T; p.E143V; 16:1324744-1324744	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.448G>A; p.A150T; 16:1324764-1324764	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.309G>C; p.W103C; 16:1320259-1320259	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.332A>T; p.Q111L; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.239C>T; p.P80L; 16:1320189-1320189	skin	malignant_melanoma	Substitution - Missense
c.332A>C; p.Q111P; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.332A>C; p.Q111P; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.332A>C; p.Q111P; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.332A>C; p.Q111P; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.332A>C; p.Q111P; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.66T>G; p.F22L; 16:1314096-1314096	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.332A>C; p.Q111P; 16:1320282-1320282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.446G>A; p.R149Q; 16:1324762-1324762	urinary_tract; bladder	carcinoma	Substitution - Missense
c.432C>T; p.Y144Y; 16:1324748-1324748	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.432C>T; p.Y144Y; 16:1324748-1324748	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation