Cancer metastasis database

Annotation category 5

Gene information

Gene ID 7280
Symbol

TUBB2A

Synonymous

CDCBM5|TUBB|TUBB2|dJ40E16.7

Full name

tubulin, beta 2A class IIa

Gene description

class IIa beta-tubulin|tubulin beta class IIa|tubulin beta-2A chain|tubulin, beta polypeptide 2

Cytoband

6p25

Gene type

protein-coding

Synonymous

MIM:615101; HGNC:HGNC:12412; Ensembl:ENSG00000137267; HPRD:01852; Vega:OTTHUMG00000014135

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.743C>T; p.A248V; 6:3154458-3154458

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.743C>T; p.A248V; 6:3154458-3154458

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.743C>T; p.A248V; 6:3154458-3154458

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.553G>A; p.A185T; 6:3154648-3154648

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.553G>A; p.A185T; 6:3154648-3154648

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1282G>A; p.A428T; 6:3153919-3153919

 large_intestine; colonNSSubstitution - Missense

c.553G>A; p.A185T; 6:3154648-3154648

 breastcarcinomaSubstitution - Missense

c.1282G>A; p.A428T; 6:3153919-3153919

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.977T>G; p.V326G; 6:3154224-3154224

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1186C>T; p.H396Y; 6:3154015-3154015

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.501C>T; p.F167F; 6:3154700-3154700

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1057G>A; p.V353M; 6:3154144-3154144

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.618C>G; p.A206A; 6:3154583-3154583

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.619C>A; p.L207M; 6:3154582-3154582

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.270C>T; p.F90F; 6:3155632-3155632

 skinmalignant_melanomaSubstitution - coding silent

c.1295A>G; p.E432G; 6:3153906-3153906

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.636C>T; p.F212F; 6:3154565-3154565

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.666C>T; p.Y222Y; 6:3154535-3154535

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.584delA; p.N195fs*21; 6:3154617-3154617

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.607G>C; p.D203H; 6:3154594-3154594

 stomachadenocarcinomaSubstitution - Missense

c.1300G>A; p.G434R; 6:3153901-3153901

 skinmalignant_melanomaSubstitution - Missense

c.603C>A; p.S201S; 6:3154598-3154598

 skinmalignant_melanomaSubstitution - coding silent

c.429G>A; p.T143T; 6:3154772-3154772

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.637C>T; p.R213C; 6:3154564-3154564

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1308C>T; p.F436F; 6:3153893-3153893

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1308C>T; p.F436F; 6:3153893-3153893

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.14T>C; p.V5A; 6:3157450-3157450

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1287G>A; p.T429T; 6:3153914-3153914

 ovaryother; neoplasmSubstitution - coding silent

c.638G>A; p.R213H; 6:3154563-3154563

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.230G>C; p.R77T; 6:3155672-3155672

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1249G>A; p.D417N; 6:3153952-3153952

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.667_668GG>AA; p.G223K; 6:3154533-3154534

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.361A>G; p.R121G; 6:3154840-3154840

 small_intestinecarcinoid-endocrine_tumourSubstitution - Missense

c.144C>T; p.N48N; 6:3156066-3156066

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.292G>A; p.G98R; 6:3154909-3154909

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.178G>T; p.V60L; 6:3155724-3155724

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.564T>G; p.S188S; 6:3154637-3154637

 thyroidother; neoplasmSubstitution - coding silent

c.564T>G; p.S188S; 6:3154637-3154637

 thyroidother; neoplasmSubstitution - coding silent

c.564T>G; p.S188S; 6:3154637-3154637

 thyroidother; neoplasmSubstitution - coding silent

c.564T>G; p.S188S; 6:3154637-3154637

 thyroidother; neoplasmSubstitution - coding silent

c.284G>A; p.S95N; 6:3154917-3154917

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.284G>A; p.S95N; 6:3154917-3154917

 skinmalignant_melanomaSubstitution - Missense

c.215C>T; p.T72I; 6:3155687-3155687

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1290C>T; p.A430A; 6:3153911-3153911

 skinmalignant_melanomaSubstitution - coding silent

c.1260C>A; p.S420S; 6:3153941-3153941

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1301G>A; p.G434E; 6:3153900-3153900

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.13G>T; p.V5L; 6:3157451-3157451

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.205G>A; p.E69K; 6:3155697-3155697

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.651G>C; p.L217L; 6:3154550-3154550

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.612C>T; p.N204N; 6:3154589-3154589

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1293C>T; p.D431D; 6:3153908-3153908

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.96C>T; p.P32P; 6:3156114-3156114

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1320G>C; p.E440D; 6:3153881-3153881

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense