lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	7145
Symbol	TNS1
Synonymous	MST091\|MST122\|MST127\|MSTP091\|MSTP122\|MSTP127\|MXRA6\|PPP1R155\|TNS
Full name	tensin 1
Gene description	Matrix-remodelling-associated protein 6\|matrix-remodelling associated 6\|protein phosphatase 1, regulatory subunit 155\|tensin-1
Cytoband	2q35-q36
Gene type	protein-coding
Synonymous	MIM:600076; HGNC:HGNC:11973; Ensembl:ENSG00000079308; HPRD:02512; Vega:OTTHUMG00000133056

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.3230C>A; p.S1077Y; 2:217821770-217821770	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2562T>G; p.T854T; 2:217847580-217847580	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.207G>A; p.K69K; 2:217895018-217895018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4517C>A; p.P1506Q; 2:217813717-217813717	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1998G>A; p.Q666Q; 2:217848144-217848144	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1037G>A; p.R346Q; 2:217880915-217880915	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1037G>A; p.R346Q; 2:217880915-217880915	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.2204C>T; p.P735L; 2:217847938-217847938	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.373G>A; p.A125T; 2:217892982-217892982	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1396C>T; p.R466C; 2:217848746-217848746	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1037G>A; p.R346Q; 2:217880915-217880915	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.920G>A; p.G307E; 2:217882363-217882363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.544A>T; p.K182*; 2:217886594-217886594	kidney	other; neoplasm	Substitution - Nonsense
c.4099G>A; p.A1367T; 2:217817921-217817921	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4946C>T; p.T1649I; 2:217809838-217809838	liver	carcinoma	Substitution - Missense
c.3541C>T; p.R1181C; 2:217818479-217818479	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.4988T>A; p.L1663H; 2:217808645-217808645	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3406C>T; p.P1136S; 2:217818614-217818614	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3196C>T; p.L1066L; 2:217821804-217821804	pancreas	carcinoma	Substitution - coding silent
c.150A>G; p.K50K; 2:217897816-217897816	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3528G>A; p.G1176G; 2:217818492-217818492	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.3800C>T; p.P1267L; 2:217818220-217818220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.709G>A; p.E237K; 2:217885776-217885776	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3488G>A; p.R1163Q; 2:217818532-217818532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1595delG; p.G532fs*9; 2:217848547-217848547	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.938-4T>G; p.?; 2:217881018-217881018	oesophagus	carcinoma; adenocarcinoma	Unknown
c.1413G>A; p.S471S; 2:217848729-217848729	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2780C>T; p.P927L; 2:217836064-217836064	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1409delG; p.G470fs*23; 2:217848733-217848733	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1724C>T; p.T575M; 2:217848418-217848418	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4306G>A; p.D1436N; 2:217817714-217817714	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1400C>T; p.P467L; 2:217848742-217848742	skin	malignant_melanoma	Substitution - Missense
c.1522C>T; p.Q508*; 2:217848620-217848620	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1400C>T; p.P467L; 2:217848742-217848742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4423G>A; p.A1475T; 2:217813811-217813811	pancreas	carcinoma	Substitution - Missense
c.1400C>T; p.P467L; 2:217848742-217848742	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4363T>G; p.F1455V; 2:217814966-217814966	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3010C>T; p.R1004W; 2:217830379-217830379	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1583C>T; p.T528I; 2:217848559-217848559	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.4423G>A; p.A1475T; 2:217813811-217813811	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2918_2919insC; p.L975fs*37; 2:217831534-217831535	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2918_2919insC; p.L975fs*37; 2:217831534-217831535	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1160C>A; p.P387H; 2:217848982-217848982	breast	carcinoma	Substitution - Missense
c.4692G>A; p.L1564L; 2:217812396-217812396	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3726delG; p.S1243fs*50; 2:217818294-217818294	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2033G>A; p.S678N; 2:217848109-217848109	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2362C>T; p.P788S; 2:217847780-217847780	skin	malignant_melanoma	Substitution - Missense
c.3600C>G; p.I1200M; 2:217818420-217818420	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1157G>A; p.R386H; 2:217848985-217848985	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4126G>A; p.A1376T; 2:217817894-217817894	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2759C>T; p.S920F; 2:217836085-217836085	skin	malignant_melanoma	Substitution - Missense
c.630C>G; p.Y210*; 2:217886079-217886079	stomach	adenocarcinoma	Substitution - Nonsense
c.3956G>A; p.R1319Q; 2:217818064-217818064	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2819G>A; p.R940Q; 2:217836025-217836025	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1313G>A; p.R438Q; 2:217848829-217848829	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2575C>T; p.R859W; 2:217847567-217847567	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2575C>T; p.R859W; 2:217847567-217847567	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1070C>T; p.T357M; 2:217849072-217849072	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.4486G>A; p.A1496T; 2:217813748-217813748	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1929G>A; p.V643V; 2:217848213-217848213	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.2860G>A; p.E954K; 2:217835136-217835136	urinary_tract; bladder	carcinoma	Substitution - Missense
c.747G>T; p.K249N; 2:217885159-217885159	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3571C>G; p.P1191A; 2:217818449-217818449	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2518C>T; p.P840S; 2:217847624-217847624	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4443G>T; p.E1481D; 2:217813791-217813791	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3221G>A; p.S1074N; 2:217821779-217821779	breast	carcinoma	Substitution - Missense
c.522C>T; p.S174S; 2:217886616-217886616	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.146C>A; p.S49Y; 2:217897820-217897820	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1678C>A; p.P560T; 2:217848464-217848464	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.610C>T; p.R204W; 2:217886099-217886099	urinary_tract; bladder	carcinoma	Substitution - Missense
c.610C>T; p.R204W; 2:217886099-217886099	skin	malignant_melanoma	Substitution - Missense
c.1312C>T; p.R438W; 2:217848830-217848830	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.610C>T; p.R204W; 2:217886099-217886099	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.2756G>A; p.R919H; 2:217836088-217836088	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2719T>C; p.S907P; 2:217836125-217836125	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2883G>A; p.P961P; 2:217835113-217835113	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2600A>C; p.N867T; 2:217847542-217847542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.564C>T; p.H188H; 2:217886574-217886574	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2461G>A; p.A821T; 2:217847681-217847681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1107G>A; p.V369V; 2:217849035-217849035	large_intestine; rectum	NS	Substitution - coding silent
c.646G>A; p.V216M; 2:217886063-217886063	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3939C>A; p.G1313G; 2:217818081-217818081	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1533C>G; p.H511Q; 2:217848609-217848609	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3279C>A; p.F1093L; 2:217818741-217818741	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.4462C>A; p.R1488S; 2:217813772-217813772	prostate	adenoma	Substitution - Missense
c.4491C>T; p.Y1497Y; 2:217813743-217813743	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3903C>T; p.G1301G; 2:217818117-217818117	skin	malignant_melanoma	Substitution - coding silent
c.4378_4380delTCT; p.S1460delS; 2:217814949-217814951	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - In frame
c.4523C>T; p.P1508L; 2:217813711-217813711	skin; shoulder	malignant_melanoma	Substitution - Missense
c.1176C>T; p.T392T; 2:217848966-217848966	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1337G>T; p.G446V; 2:217848805-217848805	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3346C>T; p.R1116C; 2:217818674-217818674	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3843C>T; p.G1281G; 2:217818177-217818177	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.665A>G; p.Y222C; 2:217886044-217886044	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.73G>A; p.V25I; 2:217897893-217897893	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1538C>T; p.A513V; 2:217848604-217848604	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3896G>A; p.S1299N; 2:217818124-217818124	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.73G>A; p.V25I; 2:217897893-217897893	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3399C>T; p.S1133S; 2:217818621-217818621	skin	malignant_melanoma	Substitution - coding silent
c.4642+2T>C; p.?; 2:217813213-217813213	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2799C>T; p.I933I; 2:217836045-217836045	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1790A>C; p.H597P; 2:217848352-217848352	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.5109C>T; p.N1703N; 2:217804558-217804558	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2463C>A; p.A821A; 2:217847679-217847679	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3135G>T; p.K1045N; 2:217821865-217821865	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.1003C>T; p.R335C; 2:217880949-217880949	skin	malignant_melanoma	Substitution - Missense
c.3621delC; p.S1208fs*5; 2:217818399-217818399	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.204G>A; p.T68T; 2:217895021-217895021	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5080G>A; p.A1694T; 2:217804587-217804587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1036C>T; p.R346*; 2:217880916-217880916	skin	malignant_melanoma	Substitution - Nonsense
c.120C>T; p.L40L; 2:217897846-217897846	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2458C>T; p.P820S; 2:217847684-217847684	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2454C>T; p.S818S; 2:217847688-217847688	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.4318T>C; p.Y1440H; 2:217817702-217817702	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.615A>G; p.P205P; 2:217886094-217886094	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3384G>T; p.Q1128H; 2:217818636-217818636	thyroid	other; neoplasm	Substitution - Missense
c.2037G>A; p.R679R; 2:217848105-217848105	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.615A>G; p.P205P; 2:217886094-217886094	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.5181C>T; p.V1727V; 2:217804486-217804486	skin	malignant_melanoma	Substitution - coding silent
c.1469G>C; p.G490A; 2:217848673-217848673	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1239C>A; p.T413T; 2:217848903-217848903	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.24_26delGGA; p.E8delE; 2:217897940-217897942	pancreas	carcinoma; adenocarcinoma	Deletion - In frame
c.2928C>T; p.A976A; 2:217831525-217831525	skin	malignant_melanoma	Substitution - coding silent
c.3980C>G; p.S1327C; 2:217818040-217818040	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2128G>A; p.E710K; 2:217848014-217848014	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1475T>A; p.L492*; 2:217848667-217848667	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Nonsense
c.108_109CC>TT; p.R37W; 2:217897857-217897858	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4537C>T; p.Q1513*; 2:217813697-217813697	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3307C>A; p.P1103T; 2:217818713-217818713	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.4537C>T; p.Q1513*; 2:217813697-217813697	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2102C>T; p.S701F; 2:217848040-217848040	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4612C>T; p.L1538F; 2:217813245-217813245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.611G>A; p.R204Q; 2:217886098-217886098	pancreas	carcinoma	Substitution - Missense
c.2056G>A; p.A686T; 2:217848086-217848086	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4446G>A; p.P1482P; 2:217813788-217813788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2320G>A; p.G774R; 2:217847822-217847822	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4043C>A; p.P1348H; 2:217817977-217817977	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3314C>T; p.T1105M; 2:217818706-217818706	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2686C>T; p.R896W; 2:217836158-217836158	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1569C>T; p.D523D; 2:217848573-217848573	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.5051G>A; p.G1684D; 2:217808087-217808087	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4893G>A; p.T1631T; 2:217809891-217809891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4724C>A; p.P1575H; 2:217810316-217810316	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3835C>A; p.H1279N; 2:217818185-217818185	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1910delG; p.G637fs*11; 2:217848232-217848232	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1946C>T; p.S649L; 2:217848196-217848196	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2077C>A; p.L693I; 2:217848065-217848065	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.4059C>T; p.F1353F; 2:217817961-217817961	skin	malignant_melanoma	Substitution - coding silent
c.4462C>T; p.R1488C; 2:217813772-217813772	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4788G>A; p.G1596G; 2:217810252-217810252	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4093A>C; p.S1365R; 2:217817927-217817927	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3912C>T; p.L1304L; 2:217818108-217818108	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2284T>C; p.S762P; 2:217847858-217847858	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5195G>A; p.G1732D; 2:217804472-217804472	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4976G>A; p.R1659H; 2:217808657-217808657	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1855T>A; p.S619T; 2:217848287-217848287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.832G>T; p.V278F; 2:217885074-217885074	skin; ankle	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.3383A>C; p.Q1128P; 2:217818637-217818637	thyroid	other; neoplasm	Substitution - Missense
c.2348C>T; p.S783F; 2:217847794-217847794	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4737G>A; p.S1579S; 2:217810303-217810303	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3593G>A; p.R1198Q; 2:217818427-217818427	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.5195G>T; p.G1732V; 2:217804472-217804472	breast	carcinoma	Substitution - Missense
c.1750G>A; p.A584T; 2:217848392-217848392	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3486T>C; p.A1162A; 2:217818534-217818534	thyroid	other; neoplasm	Substitution - coding silent
c.3152C>A; p.A1051D; 2:217821848-217821848	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3511G>A; p.V1171I; 2:217818509-217818509	pancreas	carcinoma	Substitution - Missense
c.2918delC; p.P973fs*13; 2:217831535-217831535	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.5192C>T; p.A1731V; 2:217804475-217804475	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1506C>T; p.D502D; 2:217848636-217848636	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2918delC; p.P973fs*13; 2:217831535-217831535	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2918delC; p.P973fs*13; 2:217831535-217831535	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2918delC; p.P973fs*13; 2:217831535-217831535	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2918delC; p.P973fs*13; 2:217831535-217831535	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.577G>A; p.G193S; 2:217886561-217886561	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1412C>T; p.S471L; 2:217848730-217848730	thyroid	carcinoma	Substitution - Missense
c.1853G>A; p.R618H; 2:217848289-217848289	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1853G>A; p.R618H; 2:217848289-217848289	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2311C>T; p.H771Y; 2:217847831-217847831	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3281C>T; p.P1094L; 2:217818739-217818739	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2311C>T; p.H771Y; 2:217847831-217847831	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.262G>A; p.E88K; 2:217893519-217893519	NS	malignant_melanoma	Substitution - Missense
c.262G>A; p.E88K; 2:217893519-217893519	NS	malignant_melanoma	Substitution - Missense
c.3169C>T; p.H1057Y; 2:217821831-217821831	skin; arm	malignant_melanoma	Substitution - Missense
c.1837C>A; p.P613T; 2:217848305-217848305	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2712G>T; p.E904D; 2:217836132-217836132	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1588G>A; p.E530K; 2:217848554-217848554	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3905G>A; p.R1302H; 2:217818115-217818115	skin	malignant_melanoma	Substitution - Missense
c.2659G>A; p.A887T; 2:217836185-217836185	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4536G>T; p.Q1512H; 2:217813698-217813698	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2210C>A; p.A737D; 2:217847932-217847932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.70G>T; p.A24S; 2:217897896-217897896	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>C; p.G53R; 2:217897809-217897809	pancreas	carcinoma	Substitution - Missense
c.1080A>T; p.P360P; 2:217849062-217849062	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2576G>A; p.R859Q; 2:217847566-217847566	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2285C>T; p.S762F; 2:217847857-217847857	skin; trunk	malignant_melanoma	Substitution - Missense
c.4050G>A; p.T1350T; 2:217817970-217817970	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.166C>A; p.L56M; 2:217897800-217897800	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1558T>C; p.S520P; 2:217848584-217848584	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3096A>C; p.T1032T; 2:217821904-217821904	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2316G>A; p.S772S; 2:217847826-217847826	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4732G>T; p.E1578*; 2:217810308-217810308	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.4123G>A; p.A1375T; 2:217817897-217817897	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3226delC; p.L1076fs*137; 2:217821774-217821774	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4269T>C; p.S1423S; 2:217817751-217817751	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.374C>T; p.A125V; 2:217892981-217892981	oesophagus	carcinoma	Substitution - Missense
c.997C>T; p.L333F; 2:217880955-217880955	skin; mucosal	malignant_melanoma	Substitution - Missense
c.1788C>A; p.P596P; 2:217848354-217848354	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.5084G>A; p.R1695Q; 2:217804583-217804583	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1521C>A; p.N507K; 2:217848621-217848621	ovary	other; neoplasm	Substitution - Missense
c.3533C>T; p.P1178L; 2:217818487-217818487	skin	malignant_melanoma	Substitution - Missense
c.867C>A; p.F289L; 2:217885039-217885039	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3517A>T; p.T1173S; 2:217818503-217818503	liver	carcinoma	Substitution - Missense
c.300G>A; p.W100*; 2:217893481-217893481	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.867C>A; p.F289L; 2:217885039-217885039	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.4872G>A; p.E1624E; 2:217809912-217809912	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4908C>T; p.I1636I; 2:217809876-217809876	skin	malignant_melanoma	Substitution - coding silent
c.1760G>T; p.G587V; 2:217848382-217848382	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.784G>A; p.V262I; 2:217885122-217885122	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.2387A>G; p.Y796C; 2:217847755-217847755	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4908C>T; p.I1636I; 2:217809876-217809876	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1366G>A; p.A456T; 2:217848776-217848776	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4301T>A; p.L1434Q; 2:217817719-217817719	pancreas	carcinoma	Substitution - Missense
c.2256C>T; p.S752S; 2:217847886-217847886	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1266C>T; p.V422V; 2:217848876-217848876	skin	malignant_melanoma	Substitution - coding silent
c.4251C>T; p.S1417S; 2:217817769-217817769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2041A>G; p.S681G; 2:217848101-217848101	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2741G>A; p.R914H; 2:217836103-217836103	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1655C>T; p.P552L; 2:217848487-217848487	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2648A>C; p.E883A; 2:217836196-217836196	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3723_3724GG>AA; p.G1242R; 2:217818296-217818297	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1487G>A; p.R496Q; 2:217848655-217848655	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1487G>A; p.R496Q; 2:217848655-217848655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1487G>A; p.R496Q; 2:217848655-217848655	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3987G>A; p.P1329P; 2:217818033-217818033	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1352G>A; p.R451Q; 2:217848790-217848790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3964G>A; p.A1322T; 2:217818056-217818056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.856G>A; p.D286N; 2:217885050-217885050	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2927C>T; p.A976V; 2:217831526-217831526	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.349C>T; p.R117*; 2:217893006-217893006	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Nonsense
c.1432C>T; p.R478C; 2:217848710-217848710	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4379C>T; p.S1460F; 2:217814950-217814950	pancreas	carcinoma	Substitution - Missense
c.623G>A; p.R208H; 2:217886086-217886086	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.977A>T; p.D326V; 2:217880975-217880975	skin	malignant_melanoma	Substitution - Missense
c.3380C>T; p.A1127V; 2:217818640-217818640	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.578G>A; p.G193D; 2:217886560-217886560	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.5076C>T; p.F1692F; 2:217804591-217804591	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.573G>A; p.M191I; 2:217886565-217886565	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.943G>A; p.E315K; 2:217881009-217881009	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2105A>T; p.Q702L; 2:217848037-217848037	thyroid	other; neoplasm	Substitution - Missense
c.4168C>T; p.R1390*; 2:217817852-217817852	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3375G>A; p.P1125P; 2:217818645-217818645	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3375G>A; p.P1125P; 2:217818645-217818645	breast	carcinoma	Substitution - coding silent
c.3375G>A; p.P1125P; 2:217818645-217818645	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2800G>A; p.A934T; 2:217836044-217836044	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3382C>T; p.Q1128*; 2:217818638-217818638	thyroid	other; neoplasm	Substitution - Nonsense
c.2106G>A; p.Q702Q; 2:217848036-217848036	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4617G>A; p.K1539K; 2:217813240-217813240	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1296G>C; p.L432F; 2:217848846-217848846	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2034C>T; p.S678S; 2:217848108-217848108	liver	carcinoma	Substitution - coding silent
c.1002C>T; p.I334I; 2:217880950-217880950	skin	malignant_melanoma	Substitution - coding silent
c.2034C>T; p.S678S; 2:217848108-217848108	liver	carcinoma	Substitution - coding silent
c.1002C>T; p.I334I; 2:217880950-217880950	skin	malignant_melanoma	Substitution - coding silent
c.31T>C; p.C11R; 2:217897935-217897935	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1683C>T; p.Y561Y; 2:217848459-217848459	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.491+10T>G; p.?; 2:217890952-217890952	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.1890C>T; p.P630P; 2:217848252-217848252	skin	malignant_melanoma	Substitution - coding silent
c.2559G>A; p.A853A; 2:217847583-217847583	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.2559G>A; p.A853A; 2:217847583-217847583	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2559G>A; p.A853A; 2:217847583-217847583	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3022G>A; p.E1008K; 2:217830367-217830367	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3343T>G; p.F1115V; 2:217818677-217818677	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4641C>T; p.F1547F; 2:217813216-217813216	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3474G>A; p.P1158P; 2:217818546-217818546	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3474G>A; p.P1158P; 2:217818546-217818546	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.411G>A; p.A137A; 2:217891042-217891042	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4820T>C; p.V1607A; 2:217809964-217809964	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2905+1G>A; p.?; 2:217835090-217835090	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.5046G>T; p.E1682D; 2:217808092-217808092	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2755C>T; p.R919C; 2:217836089-217836089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2091G>A; p.P697P; 2:217848051-217848051	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3714G>A; p.A1238A; 2:217818306-217818306	skin	malignant_melanoma	Substitution - coding silent
c.991G>A; p.D331N; 2:217880961-217880961	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3714G>A; p.A1238A; 2:217818306-217818306	skin	malignant_melanoma	Substitution - coding silent
c.203C>T; p.T68M; 2:217895022-217895022	pancreas	carcinoma	Substitution - Missense
c.203C>T; p.T68M; 2:217895022-217895022	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1711C>T; p.H571Y; 2:217848431-217848431	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4340C>T; p.P1447L; 2:217814989-217814989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3310C>T; p.R1104W; 2:217818710-217818710	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4340C>T; p.P1447L; 2:217814989-217814989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3247C>T; p.L1083F; 2:217821753-217821753	skin	malignant_melanoma	Substitution - Missense
c.746A>G; p.K249R; 2:217885160-217885160	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.877C>T; p.R293*; 2:217882406-217882406	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2951G>A; p.G984D; 2:217831502-217831502	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1881C>G; p.P627P; 2:217848261-217848261	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.292G>T; p.D98Y; 2:217893489-217893489	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733G>T; p.D245Y; 2:217885752-217885752	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2466C>T; p.F822F; 2:217847676-217847676	skin	malignant_melanoma	Substitution - coding silent
c.2752G>T; p.V918F; 2:217836092-217836092	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1685A>T; p.E562V; 2:217848457-217848457	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4516C>T; p.P1506S; 2:217813718-217813718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1175C>T; p.T392I; 2:217848967-217848967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3913G>T; p.G1305*; 2:217818107-217818107	thyroid	other; neoplasm	Substitution - Nonsense
c.2908C>T; p.R970W; 2:217831545-217831545	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2546C>T; p.S849L; 2:217847596-217847596	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3721_3722CC>TT; p.P1241L; 2:217818298-217818299	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3750A>G; p.P1250P; 2:217818270-217818270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2245C>T; p.L749F; 2:217847897-217847897	skin	malignant_melanoma	Substitution - Missense
c.3535C>G; p.Q1179E; 2:217818485-217818485	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4143C>A; p.S1381R; 2:217817877-217817877	breast	carcinoma	Substitution - Missense
c.4296C>G; p.H1432Q; 2:217817724-217817724	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3185G>T; p.R1062M; 2:217821815-217821815	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3543C>T; p.R1181R; 2:217818477-217818477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3937G>A; p.G1313S; 2:217818083-217818083	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3934C>T; p.P1312S; 2:217818086-217818086	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3934C>T; p.P1312S; 2:217818086-217818086	skin	malignant_melanoma	Substitution - Missense
c.3585C>T; p.F1195F; 2:217818435-217818435	skin	malignant_melanoma	Substitution - coding silent
c.21_23delGGA; p.E8delE; 2:217897943-217897945	breast	carcinoma	Deletion - In frame
c.2471C>T; p.P824L; 2:217847671-217847671	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2471C>T; p.P824L; 2:217847671-217847671	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3484G>A; p.A1162T; 2:217818536-217818536	thyroid	other; neoplasm	Substitution - Missense
c.1648A>G; p.M550V; 2:217848494-217848494	breast	carcinoma	Substitution - Missense
c.325G>A; p.V109I; 2:217893456-217893456	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1197G>C; p.T399T; 2:217848945-217848945	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2649G>T; p.E883D; 2:217836195-217836195	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2918C>T; p.P973L; 2:217831535-217831535	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1755G>T; p.Q585H; 2:217848387-217848387	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	breast	carcinoma	Deletion - In frame
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	breast	carcinoma	Deletion - In frame
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.1947G>A; p.S649S; 2:217848195-217848195	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.708C>T; p.I236I; 2:217885777-217885777	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - In frame
c.1947G>A; p.S649S; 2:217848195-217848195	thyroid	other; neoplasm	Substitution - coding silent
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.375G>A; p.A125A; 2:217892980-217892980	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.375G>A; p.A125A; 2:217892980-217892980	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1976_1978delAGC; p.Q659delQ; 2:217848164-217848166	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.459G>C; p.K153N; 2:217890994-217890994	ovary	other; neoplasm	Substitution - Missense
c.703A>G; p.T235A; 2:217885782-217885782	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3182T>C; p.L1061P; 2:217821818-217821818	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4892C>T; p.T1631M; 2:217809892-217809892	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1614C>T; p.S538S; 2:217848528-217848528	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.385C>T; p.H129Y; 2:217892970-217892970	skin	malignant_melanoma	Substitution - Missense
c.383T>C; p.M128T; 2:217892972-217892972	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2110G>A; p.E704K; 2:217848032-217848032	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4401G>T; p.E1467D; 2:217814928-217814928	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.69C>T; p.I23I; 2:217897897-217897897	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4909G>A; p.V1637I; 2:217809875-217809875	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3374C>T; p.P1125L; 2:217818646-217818646	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2301C>T; p.I767I; 2:217847841-217847841	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2999-2A>T; p.?; 2:217830392-217830392	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.4963C>A; p.L1655I; 2:217808670-217808670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3539C>T; p.A1180V; 2:217818481-217818481	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.5030+2T>A; p.?; 2:217808601-217808601	stomach	carcinoma; adenocarcinoma	Unknown
c.4476C>T; p.S1492S; 2:217813758-217813758	liver	carcinoma	Substitution - coding silent
c.1729C>T; p.P577S; 2:217848413-217848413	skin; arm	malignant_melanoma	Substitution - Missense
c.1646C>T; p.P549L; 2:217848496-217848496	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3334G>A; p.E1112K; 2:217818686-217818686	skin	malignant_melanoma	Substitution - Missense
c.999C>G; p.L333L; 2:217880953-217880953	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.878G>A; p.R293Q; 2:217882405-217882405	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1017C>T; p.Y339Y; 2:217880935-217880935	breast	carcinoma	Substitution - coding silent
c.4265C>T; p.P1422L; 2:217817755-217817755	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5138C>T; p.P1713L; 2:217804529-217804529	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4524A>T; p.P1508P; 2:217813710-217813710	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.3381C>A; p.A1127A; 2:217818639-217818639	thyroid	other; neoplasm	Substitution - coding silent
c.1566G>T; p.L522L; 2:217848576-217848576	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4538A>G; p.Q1513R; 2:217813696-217813696	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3913G>A; p.G1305R; 2:217818107-217818107	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4446G>C; p.P1482P; 2:217813788-217813788	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.4917C>G; p.F1639L; 2:217809867-217809867	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4657C>G; p.L1553V; 2:217812431-217812431	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3817G>T; p.G1273C; 2:217818203-217818203	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1640C>T; p.S547F; 2:217848502-217848502	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4128C>T; p.A1376A; 2:217817892-217817892	skin	malignant_melanoma	Substitution - coding silent
c.4133G>A; p.R1378Q; 2:217817887-217817887	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4133G>A; p.R1378Q; 2:217817887-217817887	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3371G>A; p.S1124N; 2:217818649-217818649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2901T>C; p.S967S; 2:217835095-217835095	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4498G>A; p.A1500T; 2:217813736-217813736	skin; shoulder	malignant_melanoma	Substitution - Missense
c.3676C>T; p.H1226Y; 2:217818344-217818344	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1981C>T; p.R661C; 2:217848161-217848161	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1904G>A; p.R635Q; 2:217848238-217848238	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3280C>T; p.P1094S; 2:217818740-217818740	thyroid	carcinoma	Substitution - Missense
c.2048A>G; p.Q683R; 2:217848094-217848094	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1585A>G; p.S529G; 2:217848557-217848557	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.990C>T; p.S330S; 2:217880962-217880962	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.990C>T; p.S330S; 2:217880962-217880962	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1979_1980insAGC; p.P660_R661insA; 2:217848162-217848163	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - In frame
c.3604C>T; p.P1202S; 2:217818416-217818416	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3604C>T; p.P1202S; 2:217818416-217818416	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3155C>A; p.T1052N; 2:217821845-217821845	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3256G>T; p.D1086Y; 2:217821744-217821744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4487C>T; p.A1496V; 2:217813747-217813747	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1071G>A; p.T357T; 2:217849071-217849071	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3293G>A; p.S1098N; 2:217818727-217818727	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2252G>A; p.G751E; 2:217847890-217847890	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.4110G>A; p.P1370P; 2:217817910-217817910	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4750G>T; p.G1584C; 2:217810290-217810290	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.350G>A; p.R117Q; 2:217893005-217893005	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.350G>A; p.R117Q; 2:217893005-217893005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.5008G>A; p.D1670N; 2:217808625-217808625	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1696C>T; p.R566W; 2:217848446-217848446	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4414C>A; p.Q1472K; 2:217814915-217814915	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.26A>G; p.D9G; 2:217897940-217897940	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2139T>C; p.N713N; 2:217848003-217848003	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1018G>A; p.D340N; 2:217880934-217880934	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.275G>A; p.S92N; 2:217893506-217893506	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2633-1G>C; p.?; 2:217836212-217836212	lung	carcinoma; adenocarcinoma	Unknown
c.4239G>T; p.S1413S; 2:217817781-217817781	thyroid	other; neoplasm	Substitution - coding silent
c.126G>C; p.E42D; 2:217897840-217897840	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3825C>A; p.H1275Q; 2:217818195-217818195	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.5169C>T; p.F1723F; 2:217804498-217804498	skin	malignant_melanoma	Substitution - coding silent
c.3246C>T; p.I1082I; 2:217821754-217821754	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3862C>T; p.H1288Y; 2:217818158-217818158	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5094C>T; p.G1698G; 2:217804573-217804573	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4548delA; p.G1517fs*3; 2:217813686-217813686	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1395C>T; p.S465S; 2:217848747-217848747	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2933C>G; p.T978R; 2:217831520-217831520	thyroid	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation