Cancer metastasis database

Annotation category 5

Gene information

Gene ID 7132
Symbol

TNFRSF1A

Synonymous

CD120a|FPF|MS5|TBP1|TNF-R|TNF-R-I|TNF-R55|TNFAR|TNFR1|TNFR1-d2|TNFR55|TNFR60|p55|p55-R|p60

Full name

tumor necrosis factor receptor superfamily, member 1A

Gene description

TNF-R1|TNF-RI|TNFR-I|tumor necrosis factor binding protein 1|tumor necrosis factor receptor 1A isoform beta|tumor necrosis factor receptor superfamily member 1A|tumor necrosis factor receptor type 1|tumor necrosis factor-alpha receptor

Cytoband

12p13.2

Gene type

protein-coding

Synonymous

MIM:191190; HGNC:HGNC:11916; Ensembl:ENSG00000067182; HPRD:01861; Vega:OTTHUMG00000168267

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.317G>T; p.R106L; 12:6333742-6333742

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.531C>T; p.N177N; 12:6333089-6333089

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.625+5G>A; p.?; 12:6330848-6330848

 stomachcarcinoma; adenocarcinomaUnknown

c.154C>T; p.P52S; 12:6334130-6334130

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1109G>A; p.R370H; 12:6329571-6329571

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.985C>T; p.L329F; 12:6329850-6329850

 livercarcinomaSubstitution - Missense

c.623C>T; p.S208L; 12:6330855-6330855

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.812C>T; p.P271L; 12:6330023-6330023

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.47T>C; p.L16P; 12:6334237-6334237

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.677C>T; p.S226F; 12:6330660-6330660

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1368A>T; p.*456C; 12:6329312-6329312

 ovarycarcinoma; serous_carcinomaNonstop extension

c.1026G>T; p.E342D; 12:6329809-6329809

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.362G>A; p.R121Q; 12:6333477-6333477

 breastcarcinomaSubstitution - Missense

c.550_551+2delAAGT; p.?; 12:6333067-6333070

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1155C>T; p.I385I; 12:6329525-6329525

 skinmalignant_melanomaSubstitution - coding silent

c.681C>A; p.L227L; 12:6330656-6330656

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.213C>T; p.D71D; 12:6333846-6333846

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.68A>G; p.Y23C; 12:6334216-6334216

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.168G>A; p.S56S; 12:6334116-6334116

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.380G>T; p.C127F; 12:6333459-6333459

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.734C>T; p.S245F; 12:6330603-6330603

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.961G>A; p.A321T; 12:6329874-6329874

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.753G>A; p.S251S; 12:6330282-6330282

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.526G>T; p.E176*; 12:6333094-6333094

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.106G>T; p.D36Y; 12:6334178-6334178

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.888C>T; p.S296S; 12:6329947-6329947

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.672T>C; p.L224L; 12:6330665-6330665

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.65T>C; p.I22T; 12:6334219-6334219

 livercarcinomaSubstitution - Missense

c.1334C>T; p.A445V; 12:6329346-6329346

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1275C>T; p.L425L; 12:6329405-6329405

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.1275C>T; p.L425L; 12:6329405-6329405

 skinmalignant_melanomaSubstitution - coding silent

c.1070C>T; p.A357V; 12:6329610-6329610

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1103C>T; p.P368L; 12:6329577-6329577

 skinmalignant_melanomaSubstitution - Missense

c.432C>G; p.F144L; 12:6333407-6333407

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.46C>T; p.L16L; 12:6334238-6334238

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.237G>A; p.T79T; 12:6333822-6333822

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1326C>T; p.C442C; 12:6329354-6329354

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.368C>A; p.T123N; 12:6333471-6333471

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.998C>T; p.P333L; 12:6329837-6329837

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.740-3C>G; p.?; 12:6330298-6330298

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.1319C>T; p.A440V; 12:6329361-6329361

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.704G>T; p.R235L; 12:6330633-6330633

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1150G>A; p.E384K; 12:6329530-6329530

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.79delG; p.V27fs*8; 12:6334205-6334205

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.955C>T; p.Q319*; 12:6329880-6329880

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.955C>T; p.Q319*; 12:6329880-6329880

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.829C>G; p.P277A; 12:6330006-6330006

 breastcarcinomaSubstitution - Missense

c.841C>A; p.P281T; 12:6329994-6329994

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.529A>G; p.N177D; 12:6333091-6333091

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1278C>T; p.R426R; 12:6329402-6329402

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.740-9T>G; p.?; 12:6330304-6330304

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.1348G>A; p.A450T; 12:6329332-6329332

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.435T>G; p.N145K; 12:6333404-6333404

 thyroidother; neoplasmSubstitution - Missense

c.74C>G; p.S25*; 12:6334210-6334210

 breastcarcinomaSubstitution - Nonsense

c.236C>T; p.T79M; 12:6333823-6333823

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.999C>T; p.P333P; 12:6329836-6329836

 skinmalignant_melanomaSubstitution - coding silent

c.167C>T; p.S56L; 12:6334117-6334117

 skinmalignant_melanomaSubstitution - Missense

c.491C>T; p.T164I; 12:6333129-6333129

 skinmalignant_melanomaSubstitution - Missense

c.167C>T; p.S56L; 12:6334117-6334117

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.167C>T; p.S56L; 12:6334117-6334117

 breastcarcinomaSubstitution - Missense

c.167C>T; p.S56L; 12:6334117-6334117

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.576G>A; p.T192T; 12:6330902-6330902

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.740-9T>C; p.?; 12:6330304-6330304

 stomachcarcinoma; adenocarcinomaUnknown

c.300C>T; p.L100L; 12:6333759-6333759

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.209A>G; p.N70S; 12:6333850-6333850

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.760G>A; p.E254K; 12:6330275-6330275

 skinmalignant_melanomaSubstitution - Missense

c.567G>T; p.L189L; 12:6330911-6330911

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.842_843insT; p.T282fs*22; 12:6329992-6329993

 autonomic_ganglianeuroblastomaInsertion - Frameshift

c.1236G>A; p.P412P; 12:6329444-6329444

 central_nervous_system; braingliomaSubstitution - coding silent

c.1327G>A; p.G443S; 12:6329353-6329353

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.600G>A; p.E200E; 12:6330878-6330878

 skinmalignant_melanomaSubstitution - coding silent

c.157C>T; p.Q53*; 12:6334127-6334127

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.212A>G; p.D71G; 12:6333847-6333847

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.625+3G>T; p.?; 12:6330850-6330850

 pancreascarcinomaUnknown

c.74C>T; p.S25L; 12:6334210-6334210

 breastcarcinomaSubstitution - Missense

c.36A>G; p.P12P; 12:6341779-6341779

 breastcarcinomaSubstitution - coding silent

c.36A>G; p.P12P; 12:6341779-6341779

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.147T>C; p.Y49Y; 12:6334137-6334137

 bone; femurchondrosarcomaSubstitution - coding silent

c.147T>C; p.Y49Y; 12:6334137-6334137

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1038C>A; p.H346Q; 12:6329797-6329797

 thyroidother; neoplasmSubstitution - Missense

c.935G>A; p.R312K; 12:6329900-6329900

 thyroidother; neoplasmSubstitution - Missense

c.935G>A; p.R312K; 12:6329900-6329900

 thyroidother; neoplasmSubstitution - Missense

c.217C>T; p.P73S; 12:6333842-6333842

 skinmalignant_melanomaSubstitution - Missense

c.1239G>A; p.R413R; 12:6329441-6329441

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.344C>T; p.S115F; 12:6333495-6333495

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.985C>A; p.L329I; 12:6329850-6329850

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.619G>A; p.D207N; 12:6330859-6330859

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.457A>G; p.T153A; 12:6333382-6333382

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense