lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	7100
Symbol	TLR5
Synonymous	MELIOS\|SLE1\|SLEB1\|TIL3
Full name	toll-like receptor 5
Gene description	systemic lupus erythematosus susceptibility 1\|toll/interleukin-1 receptor-like protein 3
Cytoband	1q41-q42
Gene type	protein-coding
Synonymous	MIM:603031; HGNC:HGNC:11851; Ensembl:ENSG00000187554; HPRD:04326

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.340G>T; p.A114S; 1:223112692-223112692	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.219G>A; p.Q73Q; 1:223112813-223112813	skin	malignant_melanoma	Substitution - coding silent
c.1044G>T; p.L348L; 1:223111988-223111988	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1129G>A; p.D377N; 1:223111903-223111903	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1495G>A; p.E499K; 1:223111537-223111537	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.288C>A; p.N96K; 1:223112744-223112744	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.288C>A; p.N96K; 1:223112744-223112744	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2107G>T; p.D703Y; 1:223110925-223110925	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.526_527insT; p.D176fs*12; 1:223112505-223112506	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.813C>T; p.F271F; 1:223112219-223112219	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.200C>A; p.P67H; 1:223112832-223112832	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1940C>T; p.T647I; 1:223111092-223111092	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1533T>A; p.H511Q; 1:223111499-223111499	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.240G>A; p.Q80Q; 1:223112792-223112792	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1348C>A; p.L450I; 1:223111684-223111684	breast	carcinoma	Substitution - Missense
c.2424C>A; p.G808G; 1:223110608-223110608	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.982G>A; p.A328T; 1:223112050-223112050	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.799G>A; p.A267T; 1:223112233-223112233	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.477C>T; p.S159S; 1:223112555-223112555	skin	malignant_melanoma	Substitution - coding silent
c.232G>A; p.G78R; 1:223112800-223112800	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2571C>T; p.I857I; 1:223110461-223110461	breast	carcinoma	Substitution - coding silent
c.1464C>A; p.A488A; 1:223111568-223111568	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1464C>A; p.A488A; 1:223111568-223111568	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2080G>A; p.D694N; 1:223110952-223110952	skin	malignant_melanoma	Substitution - Missense
c.1737C>G; p.N579K; 1:223111295-223111295	skin; trunk	malignant_melanoma	Substitution - Missense
c.124C>T; p.P42S; 1:223112908-223112908	skin	malignant_melanoma	Substitution - Missense
c.200C>T; p.P67L; 1:223112832-223112832	skin	malignant_melanoma	Substitution - Missense
c.570C>T; p.L190L; 1:223112462-223112462	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.570C>T; p.L190L; 1:223112462-223112462	skin	malignant_melanoma	Substitution - coding silent
c.101G>A; p.R34H; 1:223112931-223112931	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2459A>C; p.E820A; 1:223110573-223110573	oesophagus	carcinoma	Substitution - Missense
c.1846T>C; p.F616L; 1:223111186-223111186	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1587G>A; p.R529R; 1:223111445-223111445	skin	malignant_melanoma	Substitution - coding silent
c.2567C>A; p.T856N; 1:223110465-223110465	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1219G>A; p.D407N; 1:223111813-223111813	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1219G>A; p.D407N; 1:223111813-223111813	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.85C>T; p.R29*; 1:223112947-223112947	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2318G>A; p.S773N; 1:223110714-223110714	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1294G>A; p.E432K; 1:223111738-223111738	skin	malignant_melanoma	Substitution - Missense
c.549C>A; p.F183L; 1:223112483-223112483	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1312C>A; p.L438I; 1:223111720-223111720	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.674A>C; p.N225T; 1:223112358-223112358	oesophagus	carcinoma	Substitution - Missense
c.2097C>A; p.F699L; 1:223110935-223110935	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1479C>T; p.L493L; 1:223111553-223111553	skin	malignant_melanoma	Substitution - coding silent
c.1014C>T; p.L338L; 1:223112018-223112018	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1267C>A; p.L423I; 1:223111765-223111765	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1656C>T; p.I552I; 1:223111376-223111376	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.1A>G; p.M1V; 1:223113031-223113031	lung	carcinoma; undifferentiated_carcinoma	Substitution - Missense
c.1686_1687insT; p.P563fs*2; 1:223111345-223111346	breast	carcinoma	Insertion - Frameshift
c.2136C>G; p.L712L; 1:223110896-223110896	breast	carcinoma	Substitution - coding silent
c.64C>T; p.P22S; 1:223112968-223112968	skin	malignant_melanoma	Substitution - Missense
c.731G>A; p.G244E; 1:223112301-223112301	skin	malignant_melanoma	Substitution - Missense
c.1380C>A; p.F460L; 1:223111652-223111652	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1124T>G; p.I375S; 1:223111908-223111908	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.596C>T; p.S199F; 1:223112436-223112436	skin	malignant_melanoma	Substitution - Missense
c.596C>T; p.S199F; 1:223112436-223112436	skin	malignant_melanoma	Substitution - Missense
c.802G>A; p.G268R; 1:223112230-223112230	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2262C>T; p.I754I; 1:223110770-223110770	skin	malignant_melanoma	Substitution - coding silent
c.929C>T; p.T310I; 1:223112103-223112103	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2262C>T; p.I754I; 1:223110770-223110770	skin	malignant_melanoma	Substitution - coding silent
c.866C>T; p.S289L; 1:223112166-223112166	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1404C>A; p.T468T; 1:223111628-223111628	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.84C>T; p.G28G; 1:223112948-223112948	breast	carcinoma	Substitution - coding silent
c.610G>T; p.A204S; 1:223112422-223112422	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1171C>T; p.L391F; 1:223111861-223111861	skin	malignant_melanoma	Substitution - Missense
c.1723G>A; p.D575N; 1:223111309-223111309	skin	malignant_melanoma	Substitution - Missense
c.1048G>A; p.E350K; 1:223111984-223111984	skin	malignant_melanoma	Substitution - Missense
c.2004T>C; p.F668F; 1:223111028-223111028	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.848C>T; p.A283V; 1:223112184-223112184	skin	malignant_melanoma	Substitution - Missense
c.848C>T; p.A283V; 1:223112184-223112184	central_nervous_system; brain	glioma	Substitution - Missense
c.571G>T; p.E191*; 1:223112461-223112461	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1042C>T; p.L348L; 1:223111990-223111990	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1027T>G; p.L343V; 1:223112005-223112005	skin	malignant_melanoma	Substitution - Missense
c.1404C>T; p.T468T; 1:223111628-223111628	skin	malignant_melanoma	Substitution - coding silent
c.1519C>A; p.L507M; 1:223111513-223111513	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2262C>A; p.I754I; 1:223110770-223110770	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.603delT; p.F201fs*20; 1:223112429-223112429	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1388G>C; p.C463S; 1:223111644-223111644	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.62T>G; p.I21S; 1:223112970-223112970	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.549C>T; p.F183F; 1:223112483-223112483	skin	malignant_melanoma	Substitution - coding silent
c.1579G>A; p.A527T; 1:223111453-223111453	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.445C>T; p.R149C; 1:223112587-223112587	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2375T>C; p.V792A; 1:223110657-223110657	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1880A>T; p.E627V; 1:223111152-223111152	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.445C>T; p.R149C; 1:223112587-223112587	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.445C>T; p.R149C; 1:223112587-223112587	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2366T>C; p.M789T; 1:223110666-223110666	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.792C>A; p.I264I; 1:223112240-223112240	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.699T>G; p.V233V; 1:223112333-223112333	skin	malignant_melanoma	Substitution - coding silent
c.2390A>G; p.Q797R; 1:223110642-223110642	breast	carcinoma	Substitution - Missense
c.526G>T; p.D176Y; 1:223112506-223112506	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.591G>A; p.T197T; 1:223112441-223112441	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.526G>T; p.D176Y; 1:223112506-223112506	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2537A>G; p.D846G; 1:223110495-223110495	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1866C>A; p.F622L; 1:223111166-223111166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2381C>T; p.S794F; 1:223110651-223110651	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.848C>G; p.A283G; 1:223112184-223112184	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.900delC; p.F301fs*3; 1:223112132-223112132	skin	malignant_melanoma	Deletion - Frameshift
c.1403C>A; p.T468N; 1:223111629-223111629	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1375C>T; p.R459C; 1:223111657-223111657	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.590C>T; p.T197M; 1:223112442-223112442	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.13C>T; p.L5L; 1:223113019-223113019	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.13C>T; p.L5L; 1:223113019-223113019	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.273C>T; p.F91F; 1:223112759-223112759	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.273C>T; p.F91F; 1:223112759-223112759	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.462A>C; p.K154N; 1:223112570-223112570	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.223C>A; p.L75M; 1:223112809-223112809	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1275G>A; p.A425A; 1:223111757-223111757	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1413G>T; p.E471D; 1:223111619-223111619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2311G>A; p.A771T; 1:223110721-223110721	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1337G>A; p.R446Q; 1:223111695-223111695	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.715A>G; p.T239A; 1:223112317-223112317	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.822C>G; p.I274M; 1:223112210-223112210	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1692T>A; p.N564K; 1:223111340-223111340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.968A>C; p.K323T; 1:223112064-223112064	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1553C>T; p.P518L; 1:223111479-223111479	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1397A>G; p.D466G; 1:223111635-223111635	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2010T>C; p.C670C; 1:223111022-223111022	skin	malignant_melanoma	Substitution - coding silent
c.2574C>T; p.S858S; 1:223110458-223110458	skin	malignant_melanoma	Substitution - coding silent
c.1024A>C; p.N342H; 1:223112008-223112008	breast	carcinoma	Substitution - Missense
c.2283C>A; p.H761Q; 1:223110749-223110749	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1508_1512delATCTT; p.H503fs*8; 1:223111520-223111524	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2491A>C; p.K831Q; 1:223110541-223110541	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.627T>G; p.Y209*; 1:223112405-223112405	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2548C>T; p.P850S; 1:223110484-223110484	skin	malignant_melanoma	Substitution - Missense
c.276A>G; p.R92R; 1:223112756-223112756	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1431G>T; p.Q477H; 1:223111601-223111601	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2505G>A; p.Q835Q; 1:223110527-223110527	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.756A>G; p.K252K; 1:223112276-223112276	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1107G>T; p.K369N; 1:223111925-223111925	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1466G>A; p.W489*; 1:223111566-223111566	skin; neck	malignant_melanoma	Substitution - Nonsense
c.1479C>A; p.L493L; 1:223111553-223111553	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.301G>T; p.D101Y; 1:223112731-223112731	liver	carcinoma	Substitution - Missense
c.349_350GG>AA; p.G117K; 1:223112682-223112683	skin	malignant_melanoma	Substitution - Missense
c.301G>T; p.D101Y; 1:223112731-223112731	liver	carcinoma	Substitution - Missense
c.2207C>G; p.P736R; 1:223110825-223110825	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1088C>T; p.A363V; 1:223111944-223111944	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1175G>T; p.R392L; 1:223111857-223111857	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1417C>T; p.P473S; 1:223111615-223111615	skin	malignant_melanoma	Substitution - Missense
c.472C>T; p.R158C; 1:223112560-223112560	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.472C>T; p.R158C; 1:223112560-223112560	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1017A>G; p.Q339Q; 1:223112015-223112015	skin	malignant_melanoma	Substitution - coding silent
c.2195G>T; p.R732I; 1:223110837-223110837	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.324C>A; p.Y108*; 1:223112708-223112708	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.282G>T; p.L94L; 1:223112750-223112750	breast	carcinoma	Substitution - coding silent
c.1859C>T; p.S620F; 1:223111173-223111173	skin	malignant_melanoma	Substitution - Missense
c.1633G>A; p.D545N; 1:223111399-223111399	skin	malignant_melanoma	Substitution - Missense
c.925G>A; p.E309K; 1:223112107-223112107	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1413G>A; p.E471E; 1:223111619-223111619	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.541C>A; p.Q181K; 1:223112491-223112491	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2140C>G; p.H714D; 1:223110892-223110892	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.934A>G; p.K312E; 1:223112098-223112098	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.1687C>T; p.P563S; 1:223111345-223111345	skin	malignant_melanoma	Substitution - Missense
c.205C>A; p.L69M; 1:223112827-223112827	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1336C>T; p.R446W; 1:223111696-223111696	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.663C>T; p.N221N; 1:223112369-223112369	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1159C>G; p.Q387E; 1:223111873-223111873	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.395C>G; p.S132C; 1:223112637-223112637	urinary_tract; bladder	carcinoma	Substitution - Missense
c.618T>C; p.N206N; 1:223112414-223112414	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - coding silent
c.888A>C; p.S296S; 1:223112144-223112144	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1685_1686insT; p.P563fs*2; 1:223111346-223111347	breast	carcinoma	Insertion - Frameshift
c.1776T>C; p.N592N; 1:223111256-223111256	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2549C>T; p.P850L; 1:223110483-223110483	skin	malignant_melanoma	Substitution - Missense
c.1025A>C; p.N342T; 1:223112007-223112007	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.870G>A; p.V290V; 1:223112162-223112162	skin	malignant_melanoma	Substitution - coding silent
c.384C>A; p.F128L; 1:223112648-223112648	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1775A>G; p.N592S; 1:223111257-223111257	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1775A>G; p.N592S; 1:223111257-223111257	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1775A>G; p.N592S; 1:223111257-223111257	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1775A>G; p.N592S; 1:223111257-223111257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1775A>G; p.N592S; 1:223111257-223111257	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.341C>T; p.A114V; 1:223112691-223112691	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.29G>A; p.G10E; 1:223113003-223113003	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1844C>T; p.S615L; 1:223111188-223111188	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2287C>T; p.L763F; 1:223110745-223110745	skin	malignant_melanoma	Substitution - Missense
c.801C>T; p.A267A; 1:223112231-223112231	skin	malignant_melanoma	Substitution - coding silent
c.2182T>C; p.C728R; 1:223110850-223110850	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.801C>T; p.A267A; 1:223112231-223112231	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.170A>G; p.Y57C; 1:223112862-223112862	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2233C>T; p.Q745*; 1:223110799-223110799	skin	malignant_melanoma	Substitution - Nonsense
c.2549C>A; p.P850Q; 1:223110483-223110483	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1855G>A; p.V619I; 1:223111177-223111177	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.830C>A; p.P277H; 1:223112202-223112202	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2418C>T; p.I806I; 1:223110614-223110614	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.108C>T; p.C36C; 1:223112924-223112924	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.1399C>G; p.Q467E; 1:223111633-223111633	large_intestine; caecum	adenoma	Substitution - Missense
c.536C>T; p.S179F; 1:223112496-223112496	skin	malignant_melanoma	Substitution - Missense
c.1990C>T; p.R664W; 1:223111042-223111042	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.199C>T; p.P67S; 1:223112833-223112833	skin	malignant_melanoma	Substitution - Missense
c.110A>G; p.N37S; 1:223112922-223112922	skin	malignant_melanoma	Substitution - Missense
c.742A>G; p.N248D; 1:223112290-223112290	skin	malignant_melanoma	Substitution - Missense
c.742A>G; p.N248D; 1:223112290-223112290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.139A>T; p.T47S; 1:223112893-223112893	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2193A>T; p.E731D; 1:223110839-223110839	skin; arm	malignant_melanoma	Substitution - Missense
c.1061C>T; p.S354L; 1:223111971-223111971	skin	malignant_melanoma	Substitution - Missense
c.1061C>T; p.S354L; 1:223111971-223111971	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation