lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	7097
Symbol	TLR2
Synonymous	CD282\|TIL4
Full name	toll-like receptor 2
Gene description	toll/interleukin 1 receptor-like 4\|toll/interleukin-1 receptor-like protein 4
Cytoband	4q32
Gene type	protein-coding
Synonymous	MIM:603028; HGNC:HGNC:11848; HPRD:04323

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1035C>A; p.N345K; 4:153703942-153703942	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1035C>A; p.N345K; 4:153703942-153703942	liver	carcinoma	Substitution - Missense
c.775G>T; p.V259L; 4:153703682-153703682	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.944G>A; p.R315Q; 4:153703851-153703851	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.944G>A; p.R315Q; 4:153703851-153703851	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.506A>C; p.D169A; 4:153703413-153703413	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1903C>T; p.P635S; 4:153704810-153704810	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1705C>A; p.H569N; 4:153704612-153704612	liver	carcinoma	Substitution - Missense
c.1903C>T; p.P635S; 4:153704810-153704810	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1903C>T; p.P635S; 4:153704810-153704810	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1705C>A; p.H569N; 4:153704612-153704612	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.905G>C; p.R302T; 4:153703812-153703812	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.981T>C; p.D327D; 4:153703888-153703888	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.80C>T; p.S27F; 4:153702987-153702987	skin	malignant_melanoma	Substitution - Missense
c.2223_2224insA; p.A744fs*>42; 4:153705130-153705131	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.876T>C; p.V292V; 4:153703783-153703783	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1197G>T; p.L399F; 4:153704104-153704104	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1462A>G; p.K488E; 4:153704369-153704369	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1998C>T; p.F666F; 4:153704905-153704905	skin	malignant_melanoma	Substitution - coding silent
c.1491C>G; p.L497L; 4:153704398-153704398	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1605C>T; p.F535F; 4:153704512-153704512	skin	malignant_melanoma	Substitution - coding silent
c.1350T>C; p.S450S; 4:153704257-153704257	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.710T>C; p.F237S; 4:153703617-153703617	pancreas	other; adenoma	Substitution - Missense
c.1167A>G; p.L389L; 4:153704074-153704074	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2313G>C; p.R771R; 4:153705220-153705220	skin	malignant_melanoma	Substitution - coding silent
c.983T>G; p.L328R; 4:153703890-153703890	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1043T>A; p.V348D; 4:153703950-153703950	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1710G>A; p.V570V; 4:153704617-153704617	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.948G>T; p.R316S; 4:153703855-153703855	central_nervous_system; brain	glioma	Substitution - Missense
c.1913A>C; p.N638T; 4:153704820-153704820	skin	malignant_melanoma	Substitution - Missense
c.145G>A; p.G49R; 4:153703052-153703052	skin	malignant_melanoma	Substitution - Missense
c.145G>A; p.G49R; 4:153703052-153703052	skin	malignant_melanoma	Substitution - Missense
c.980A>T; p.D327V; 4:153703887-153703887	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.980A>T; p.D327V; 4:153703887-153703887	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.713_714insT; p.S240fs*7; 4:153703620-153703621	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.980A>T; p.D327V; 4:153703887-153703887	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.980A>T; p.D327V; 4:153703887-153703887	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1716C>A; p.G572G; 4:153704623-153704623	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1360T>C; p.C454R; 4:153704267-153704267	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.139C>T; p.P47S; 4:153703046-153703046	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1554A>G; p.Q518Q; 4:153704461-153704461	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2170C>T; p.L724F; 4:153705077-153705077	skin	malignant_melanoma	Substitution - Missense
c.1751A>T; p.E584V; 4:153704658-153704658	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.563G>A; p.S188N; 4:153703470-153703470	skin	malignant_melanoma	Substitution - Missense
c.1147G>A; p.E383K; 4:153704054-153704054	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1236G>A; p.L412L; 4:153704143-153704143	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.505G>T; p.D169Y; 4:153703412-153703412	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2257C>G; p.R753G; 4:153705164-153705164	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1872G>A; p.W624*; 4:153704779-153704779	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1378G>A; p.E460K; 4:153704285-153704285	skin	malignant_melanoma	Substitution - Missense
c.437C>G; p.S146C; 4:153703344-153703344	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.437C>G; p.S146C; 4:153703344-153703344	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1909A>C; p.R637R; 4:153704816-153704816	skin	malignant_melanoma	Substitution - coding silent
c.564C>T; p.S188S; 4:153703471-153703471	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1173T>G; p.T391T; 4:153704080-153704080	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1250A>G; p.N417S; 4:153704157-153704157	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1173T>G; p.T391T; 4:153704080-153704080	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.17G>A; p.W6*; 4:153702924-153702924	breast	carcinoma	Substitution - Nonsense
c.1453T>C; p.S485P; 4:153704360-153704360	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.964T>G; p.F322V; 4:153703871-153703871	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1378G>C; p.E460Q; 4:153704285-153704285	urinary_tract; bladder	carcinoma	Substitution - Missense
c.204C>A; p.S68R; 4:153703111-153703111	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2071G>T; p.D691Y; 4:153704978-153704978	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1907G>A; p.S636N; 4:153704814-153704814	breast	carcinoma	Substitution - Missense
c.1556T>G; p.L519R; 4:153704463-153704463	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1556T>G; p.L519R; 4:153704463-153704463	genital_tract; extragonadal	germ_cell_tumour; yolk_sac_tumour	Substitution - Missense
c.2310G>A; p.Q770Q; 4:153705217-153705217	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1103G>A; p.S368N; 4:153704010-153704010	skin	malignant_melanoma	Substitution - Missense
c.1704C>T; p.S568S; 4:153704611-153704611	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.759G>A; p.K253K; 4:153703666-153703666	skin	malignant_melanoma	Substitution - coding silent
c.1822C>T; p.L608L; 4:153704729-153704729	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.500G>T; p.R167I; 4:153703407-153703407	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1694A>G; p.D565G; 4:153704601-153704601	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1266G>T; p.K422N; 4:153704173-153704173	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.746C>T; p.S249L; 4:153703653-153703653	skin	malignant_melanoma	Substitution - Missense
c.1311G>T; p.K437N; 4:153704218-153704218	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.746C>T; p.S249L; 4:153703653-153703653	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2299G>A; p.D767N; 4:153705206-153705206	skin	malignant_melanoma	Substitution - Missense
c.2243G>A; p.R748H; 4:153705150-153705150	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2070T>C; p.I690I; 4:153704977-153704977	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1548G>A; p.K516K; 4:153704455-153704455	skin	malignant_melanoma	Substitution - coding silent
c.689G>A; p.R230Q; 4:153703596-153703596	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1735C>T; p.R579C; 4:153704642-153704642	central_nervous_system; brain	glioma	Substitution - Missense
c.1735C>T; p.R579C; 4:153704642-153704642	central_nervous_system; cerebrum	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1234C>T; p.L412L; 4:153704141-153704141	skin	malignant_melanoma	Substitution - coding silent
c.2242C>T; p.R748C; 4:153705149-153705149	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1255G>A; p.D419N; 4:153704162-153704162	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.95G>A; p.R32H; 4:153703002-153703002	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.570G>A; p.E190E; 4:153703477-153703477	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1062A>T; p.L354F; 4:153703969-153703969	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.643G>A; p.E215K; 4:153703550-153703550	skin	malignant_melanoma	Substitution - Missense
c.2041C>T; p.P681S; 4:153704948-153704948	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.284C>T; p.S95F; 4:153703191-153703191	skin	malignant_melanoma	Substitution - Missense
c.1441G>T; p.E481*; 4:153704348-153704348	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.122G>A; p.G41E; 4:153703029-153703029	skin	malignant_melanoma	Substitution - Missense
c.1441G>T; p.E481*; 4:153704348-153704348	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1441G>T; p.E481*; 4:153704348-153704348	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.688C>T; p.R230*; 4:153703595-153703595	breast	carcinoma	Substitution - Nonsense
c.688C>T; p.R230*; 4:153703595-153703595	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Nonsense
c.2332C>T; p.L778L; 4:153705239-153705239	skin	malignant_melanoma	Substitution - coding silent
c.1457G>T; p.R486I; 4:153704364-153704364	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1245G>C; p.L415F; 4:153704152-153704152	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1487C>T; p.S496F; 4:153704394-153704394	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.68C>T; p.S23F; 4:153702975-153702975	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2082A>C; p.E694D; 4:153704989-153704989	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.349T>G; p.S117A; 4:153703256-153703256	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2037C>T; p.F679F; 4:153704944-153704944	ovary	other; neoplasm	Substitution - coding silent
c.459C>T; p.I153I; 4:153703366-153703366	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.636A>G; p.L212L; 4:153703543-153703543	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1163C>A; p.S388Y; 4:153704070-153704070	stomach	adenocarcinoma	Substitution - Missense
c.2166C>T; p.F722F; 4:153705073-153705073	skin	malignant_melanoma	Substitution - coding silent
c.940A>G; p.I314V; 4:153703847-153703847	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.140C>T; p.P47L; 4:153703047-153703047	skin	malignant_melanoma	Substitution - Missense
c.1073A>C; p.H358P; 4:153703980-153703980	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1054C>T; p.P352S; 4:153703961-153703961	skin	malignant_melanoma	Substitution - Missense
c.142T>G; p.S48A; 4:153703049-153703049	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1629C>T; p.S543S; 4:153704536-153704536	skin	malignant_melanoma	Substitution - coding silent
c.1431G>A; p.P477P; 4:153704338-153704338	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.847G>T; p.E283*; 4:153703754-153703754	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2168G>A; p.R723H; 4:153705075-153705075	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.673G>A; p.E225K; 4:153703580-153703580	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.332A>G; p.Y111C; 4:153703239-153703239	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1671T>C; p.D557D; 4:153704578-153704578	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1886G>T; p.R629M; 4:153704793-153704793	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.668C>T; p.S223F; 4:153703575-153703575	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.668C>T; p.S223F; 4:153703575-153703575	skin	malignant_melanoma	Substitution - Missense
c.472A>G; p.N158D; 4:153703379-153703379	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1566T>A; p.F522L; 4:153704473-153704473	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.172G>C; p.D58H; 4:153703079-153703079	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1566T>A; p.F522L; 4:153704473-153704473	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.117C>T; p.S39S; 4:153703024-153703024	pancreas	carcinoma	Substitution - coding silent
c.2121T>C; p.F707F; 4:153705028-153705028	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.769A>G; p.R257G; 4:153703676-153703676	breast	carcinoma	Substitution - Missense
c.1285C>A; p.P429T; 4:153704192-153704192	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2278A>T; p.T760S; 4:153705185-153705185	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2088C>T; p.S696S; 4:153704995-153704995	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2088C>T; p.S696S; 4:153704995-153704995	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.669C>T; p.S223S; 4:153703576-153703576	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1992G>T; p.E664D; 4:153704899-153704899	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.780A>C; p.K260N; 4:153703687-153703687	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.597T>C; p.N199N; 4:153703504-153703504	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.380C>T; p.T127I; 4:153703287-153703287	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1351G>A; p.V451I; 4:153704258-153704258	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1082C>T; p.S361L; 4:153703989-153703989	skin	malignant_melanoma	Substitution - Missense
c.1742C>T; p.S581L; 4:153704649-153704649	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1816G>A; p.G606R; 4:153704723-153704723	skin	malignant_melanoma	Substitution - Missense
c.1538C>T; p.T513M; 4:153704445-153704445	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.105C>G; p.I35M; 4:153703012-153703012	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1378G>T; p.E460*; 4:153704285-153704285	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1265A>C; p.K422T; 4:153704172-153704172	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2159C>T; p.S720F; 4:153705066-153705066	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.58G>A; p.E20K; 4:153702965-153702965	skin	malignant_melanoma	Substitution - Missense
c.342T>C; p.N114N; 4:153703249-153703249	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1539G>A; p.T513T; 4:153704446-153704446	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1169A>G; p.Q390R; 4:153704076-153704076	lung	carcinoma; undifferentiated_carcinoma	Substitution - Missense
c.2057T>A; p.I686N; 4:153704964-153704964	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2181G>T; p.E727D; 4:153705088-153705088	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1628C>T; p.S543F; 4:153704535-153704535	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1773G>A; p.V591V; 4:153704680-153704680	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.1739T>C; p.L580P; 4:153704646-153704646	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1364T>C; p.I455T; 4:153704271-153704271	liver	carcinoma	Substitution - Missense
c.1393A>T; p.S465C; 4:153704300-153704300	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1099C>T; p.L367F; 4:153704006-153704006	skin	malignant_melanoma	Substitution - Missense
c.1274T>A; p.F425Y; 4:153704181-153704181	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.76G>A; p.A26T; 4:153702983-153702983	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2202C>T; p.L734L; 4:153705109-153705109	breast	carcinoma	Substitution - coding silent
c.2236C>T; p.P746S; 4:153705143-153705143	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1192C>G; p.H398D; 4:153704099-153704099	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2236C>T; p.P746S; 4:153705143-153705143	skin	malignant_melanoma	Substitution - Missense
c.398G>T; p.G133V; 4:153703305-153703305	kidney	other; neoplasm	Substitution - Missense
c.655G>T; p.D219Y; 4:153703562-153703562	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1965G>C; p.V655V; 4:153704872-153704872	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2173T>C; p.F725L; 4:153705080-153705080	skin; acral	malignant_melanoma	Substitution - Missense
c.1591G>T; p.G531C; 4:153704498-153704498	thyroid	other; neoplasm	Substitution - Missense
c.1949G>A; p.R650Q; 4:153704856-153704856	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.637C>T; p.L213L; 4:153703544-153703544	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2257C>T; p.R753W; 4:153705164-153705164	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.476T>C; p.M159T; 4:153703383-153703383	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.893C>A; p.S298Y; 4:153703800-153703800	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.2029C>T; p.R677W; 4:153704936-153704936	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2029C>T; p.R677W; 4:153704936-153704936	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1948C>T; p.R650W; 4:153704855-153704855	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.190A>C; p.I64L; 4:153703097-153703097	kidney	other; neoplasm	Substitution - Missense
c.2029C>T; p.R677W; 4:153704936-153704936	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation