lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	7057
Symbol	THBS1
Synonymous	THBS\|THBS-1\|TSP\|TSP-1\|TSP1
Full name	thrombospondin 1
Gene description	thrombospondin-1\|thrombospondin-1p180
Cytoband	15q15
Gene type	protein-coding
Synonymous	MIM:188060; HGNC:HGNC:11785; HPRD:01765

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1410C>T; p.N470N; 15:39588157-39588157	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1410C>T; p.N470N; 15:39588157-39588157	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1768G>A; p.D590N; 15:39589081-39589081	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.763C>A; p.R255S; 15:39584047-39584047	pancreas	carcinoma	Substitution - Missense
c.1827G>C; p.E609D; 15:39589255-39589255	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.2834T>C; p.I945T; 15:39593066-39593066	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1411G>T; p.G471W; 15:39588158-39588158	thyroid	other; neoplasm	Substitution - Missense
c.2875C>T; p.R959*; 15:39593107-39593107	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1471A>G; p.I491V; 15:39588218-39588218	pancreas	carcinoma	Substitution - Missense
c.683G>A; p.R228K; 15:39583672-39583672	oesophagus	carcinoma	Substitution - Missense
c.406G>A; p.G136R; 15:39582531-39582531	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1103G>A; p.C368Y; 15:39585546-39585546	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3418G>A; p.D1140N; 15:39594353-39594353	skin	malignant_melanoma	Substitution - Missense
c.451G>A; p.G151S; 15:39582576-39582576	central_nervous_system; thalamus	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2776C>T; p.R926*; 15:39593008-39593008	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3332G>A; p.R1111H; 15:39594163-39594163	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2776C>T; p.R926*; 15:39593008-39593008	skin	malignant_melanoma	Substitution - Nonsense
c.2776C>T; p.R926*; 15:39593008-39593008	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.3214C>A; p.P1072T; 15:39593615-39593615	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.354C>T; p.S118S; 15:39582479-39582479	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1567A>G; p.T523A; 15:39588621-39588621	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1567A>G; p.T523A; 15:39588621-39588621	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1567A>G; p.T523A; 15:39588621-39588621	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1567A>G; p.T523A; 15:39588621-39588621	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1567A>G; p.T523A; 15:39588621-39588621	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1567A>G; p.T523A; 15:39588621-39588621	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2253G>A; p.R751R; 15:39591190-39591190	skin	malignant_melanoma	Substitution - coding silent
c.1235G>A; p.R412Q; 15:39587461-39587461	skin	malignant_melanoma	Substitution - Missense
c.1478G>A; p.G493E; 15:39588532-39588532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2770G>A; p.D924N; 15:39593002-39593002	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3022T>G; p.F1008V; 15:39593423-39593423	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.810C>T; p.C270C; 15:39584094-39584094	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3393C>T; p.I1131I; 15:39594328-39594328	skin	malignant_melanoma	Substitution - coding silent
c.2194_2195GA>TG; p.D732C; 15:39590564-39590565	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1728C>T; p.P576P; 15:39589041-39589041	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.184G>A; p.E62K; 15:39582309-39582309	skin	malignant_melanoma	Substitution - Missense
c.64C>T; p.P22S; 15:39581921-39581921	skin	malignant_melanoma	Substitution - Missense
c.2865C>T; p.T955T; 15:39593097-39593097	skin	malignant_melanoma	Substitution - coding silent
c.1872C>T; p.F624F; 15:39589300-39589300	skin	malignant_melanoma	Substitution - coding silent
c.1862C>A; p.P621H; 15:39589290-39589290	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.247C>T; p.R83W; 15:39582372-39582372	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3145G>A; p.D1049N; 15:39593546-39593546	skin; trunk	malignant_melanoma	Substitution - Missense
c.201delC; p.P69fs*26; 15:39582326-39582326	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.201delC; p.P69fs*26; 15:39582326-39582326	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1753C>T; p.Q585*; 15:39589066-39589066	skin	malignant_melanoma	Substitution - Nonsense
c.1839C>T; p.P613P; 15:39589267-39589267	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3001G>A; p.D1001N; 15:39593402-39593402	thyroid	carcinoma	Substitution - Missense
c.2573A>T; p.N858I; 15:39592608-39592608	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3169G>A; p.G1057R; 15:39593570-39593570	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1927-3C>T; p.?; 15:39589802-39589802	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2151T>C; p.N717N; 15:39590521-39590521	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3100C>T; p.R1034C; 15:39593501-39593501	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1088T>G; p.V363G; 15:39585531-39585531	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3321C>T; p.A1107A; 15:39594152-39594152	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2478G>A; p.M826I; 15:39591569-39591569	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.163T>A; p.S55T; 15:39582288-39582288	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2252G>T; p.R751M; 15:39590622-39590622	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1137C>T; p.D379D; 15:39587363-39587363	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2866G>A; p.D956N; 15:39593098-39593098	skin	malignant_melanoma	Substitution - Missense
c.1938C>T; p.P646P; 15:39589816-39589816	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1077C>T; p.S359S; 15:39585520-39585520	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2029G>T; p.E677*; 15:39589907-39589907	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1891G>A; p.G631S; 15:39589319-39589319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.944_945insG; p.P316fs*13; 15:39584340-39584341	liver	carcinoma	Insertion - Frameshift
c.2373T>C; p.N791N; 15:39591310-39591310	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2016C>G; p.P672P; 15:39589894-39589894	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.83A>G; p.N28S; 15:39582208-39582208	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1902C>T; p.V634V; 15:39589330-39589330	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1262G>A; p.R421Q; 15:39587488-39587488	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1902C>T; p.V634V; 15:39589330-39589330	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3271C>T; p.R1091C; 15:39594102-39594102	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3271C>T; p.R1091C; 15:39594102-39594102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.575C>A; p.A192D; 15:39582700-39582700	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.3271C>T; p.R1091C; 15:39594102-39594102	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3366-5T>C; p.?; 15:39594296-39594296	pancreas	carcinoma	Unknown
c.1970G>T; p.C657F; 15:39589848-39589848	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.2476A>G; p.M826V; 15:39591567-39591567	breast	carcinoma	Substitution - Missense
c.3366-5T>C; p.?; 15:39594296-39594296	pancreas	carcinoma	Unknown
c.1472-9T>A; p.?; 15:39588517-39588517	liver	carcinoma	Unknown
c.1472-9T>A; p.?; 15:39588517-39588517	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1674C>T; p.A558A; 15:39588987-39588987	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2387C>T; p.A796V; 15:39591324-39591324	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.439C>T; p.L147F; 15:39582564-39582564	skin	malignant_melanoma	Substitution - Missense
c.595A>T; p.I199F; 15:39582720-39582720	skin	malignant_melanoma	Substitution - Missense
c.2912C>T; p.S971F; 15:39593144-39593144	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2912C>T; p.S971F; 15:39593144-39593144	skin	malignant_melanoma	Substitution - Missense
c.645G>A; p.V215V; 15:39583634-39583634	skin	malignant_melanoma	Substitution - coding silent
c.1205G>A; p.R402H; 15:39587431-39587431	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1748G>A; p.G583D; 15:39589061-39589061	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2644C>T; p.Q882*; 15:39592679-39592679	central_nervous_system; brain	glioma	Substitution - Nonsense
c.1572C>T; p.P524P; 15:39588626-39588626	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2940C>T; p.R980R; 15:39593172-39593172	breast	carcinoma	Substitution - coding silent
c.2989G>C; p.A997P; 15:39593221-39593221	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2003A>G; p.H668R; 15:39589881-39589881	prostate	carcinoma	Substitution - Missense
c.2878T>C; p.F960L; 15:39593110-39593110	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1413G>A; p.G471G; 15:39588160-39588160	skin	malignant_melanoma	Substitution - coding silent
c.1306G>A; p.G436S; 15:39588053-39588053	skin	malignant_melanoma	Substitution - Missense
c.2252+1G>T; p.?; 15:39590623-39590623	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.2330G>A; p.C777Y; 15:39591267-39591267	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.480G>A; p.V160V; 15:39582605-39582605	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2317C>T; p.R773C; 15:39591254-39591254	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1027-6C>T; p.?; 15:39585464-39585464	kidney	other; neoplasm	Unknown
c.1407G>A; p.M469I; 15:39588154-39588154	skin	malignant_melanoma	Substitution - Missense
c.793G>A; p.D265N; 15:39584077-39584077	skin	malignant_melanoma	Substitution - Missense
c.1407G>A; p.M469I; 15:39588154-39588154	thyroid	other; neoplasm	Substitution - Missense
c.2317C>T; p.R773C; 15:39591254-39591254	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1407G>A; p.M469I; 15:39588154-39588154	skin	malignant_melanoma	Substitution - Missense
c.201C>T; p.I67I; 15:39582326-39582326	skin	malignant_melanoma	Substitution - coding silent
c.421G>A; p.V141M; 15:39582546-39582546	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.201C>T; p.I67I; 15:39582326-39582326	skin	malignant_melanoma	Substitution - coding silent
c.1412G>A; p.G471E; 15:39588159-39588159	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3071G>A; p.G1024E; 15:39593472-39593472	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3324C>A; p.Y1108*; 15:39594155-39594155	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.1517T>C; p.V506A; 15:39588571-39588571	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2535G>A; p.L845L; 15:39592570-39592570	skin	malignant_melanoma	Substitution - coding silent
c.3159G>A; p.T1053T; 15:39593560-39593560	pancreas	carcinoma	Substitution - coding silent
c.2576A>C; p.N859T; 15:39592611-39592611	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2569G>A; p.D857N; 15:39592604-39592604	skin	malignant_melanoma	Substitution - Missense
c.416A>G; p.H139R; 15:39582541-39582541	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1472T>A; p.I491N; 15:39588526-39588526	breast	carcinoma	Substitution - Missense
c.1064T>C; p.I355T; 15:39585507-39585507	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3318C>G; p.T1106T; 15:39594149-39594149	breast	carcinoma	Substitution - coding silent
c.2543_2551ACTCAGACC>TTGT; p.D848fs*8; 15:39592578-39592586	bone; humerus	chondrosarcoma	Complex - frameshift
c.1981G>A; p.A661T; 15:39589859-39589859	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.816C>T; p.I272I; 15:39584100-39584100	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3229C>T; p.R1077W; 15:39593630-39593630	breast	carcinoma	Substitution - Missense
c.3229C>T; p.R1077W; 15:39593630-39593630	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.863G>A; p.R288H; 15:39584147-39584147	oesophagus	carcinoma	Substitution - Missense
c.1701T>C; p.D567D; 15:39589014-39589014	liver	carcinoma	Substitution - coding silent
c.863G>A; p.R288H; 15:39584147-39584147	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2758G>A; p.D920N; 15:39592793-39592793	skin; extremity	malignant_melanoma	Substitution - Missense
c.644T>C; p.V215A; 15:39583633-39583633	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1868G>A; p.R623H; 15:39589296-39589296	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.503A>G; p.Y168C; 15:39582628-39582628	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1701T>C; p.D567D; 15:39589014-39589014	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.838A>G; p.M280V; 15:39584122-39584122	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.77G>A; p.G26E; 15:39582202-39582202	skin	malignant_melanoma	Substitution - Missense
c.3125A>G; p.Q1042R; 15:39593526-39593526	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1940G>A; p.R647H; 15:39589818-39589818	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.2871C>T; p.F957F; 15:39593103-39593103	skin	malignant_melanoma	Substitution - coding silent
c.2011G>A; p.D671N; 15:39589889-39589889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>A; p.E85K; 15:39582378-39582378	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2011G>A; p.D671N; 15:39589889-39589889	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1646-1G>T; p.?; 15:39588958-39588958	stomach	carcinoma; intestinal_adenocarcinoma	Unknown
c.3507T>C; p.D1169D; 15:39595363-39595363	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.603_604insG; p.V204fs*3; 15:39582728-39582729	pancreas	carcinoma; acinar_carcinoma	Insertion - Frameshift
c.291_293delGAA; p.K99delK; 15:39582416-39582418	breast	carcinoma	Deletion - In frame
c.151G>A; p.G51S; 15:39582276-39582276	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.1672G>T; p.A558S; 15:39588985-39588985	pancreas	carcinoma	Substitution - Missense
c.494C>T; p.A165V; 15:39582619-39582619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3215C>A; p.P1072H; 15:39593616-39593616	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.597C>T; p.I199I; 15:39582722-39582722	skin	malignant_melanoma	Substitution - coding silent
c.597C>T; p.I199I; 15:39582722-39582722	skin	malignant_melanoma	Substitution - coding silent
c.2263_2264insCA; p.F756fs*208; 15:39591200-39591201	breast	carcinoma	Insertion - Frameshift
c.3049G>A; p.E1017K; 15:39593450-39593450	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3049G>A; p.E1017K; 15:39593450-39593450	skin	malignant_melanoma	Substitution - Missense
c.326G>A; p.R109Q; 15:39582451-39582451	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.14G>C; p.W5S; 15:39581871-39581871	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1516G>C; p.V506L; 15:39588570-39588570	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3365+2T>C; p.?; 15:39594198-39594198	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1024C>T; p.Q342*; 15:39584420-39584420	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.890G>T; p.S297I; 15:39584174-39584174	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1889T>G; p.F630C; 15:39589317-39589317	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1227C>T; p.L409L; 15:39587453-39587453	skin	malignant_melanoma	Substitution - coding silent
c.157G>A; p.D53N; 15:39582282-39582282	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>A; p.D53N; 15:39582282-39582282	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3320C>T; p.A1107V; 15:39594151-39594151	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2691T>C; p.D897D; 15:39592726-39592726	breast	carcinoma	Substitution - coding silent
c.2757G>A; p.K919K; 15:39592792-39592792	skin	malignant_melanoma	Substitution - coding silent
c.3320C>T; p.A1107V; 15:39594151-39594151	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2265A>G; p.P755P; 15:39591202-39591202	central_nervous_system; brain	glioma	Substitution - coding silent
c.1860delC; p.P622fs*341; 15:39589288-39589288	thyroid	carcinoma; anaplastic_carcinoma	Deletion - Frameshift
c.2731A>G; p.R911G; 15:39592766-39592766	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.425C>T; p.S142F; 15:39582550-39582550	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.48T>G; p.C16W; 15:39581905-39581905	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2428C>T; p.R810W; 15:39591519-39591519	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1290G>A; p.K430K; 15:39587516-39587516	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1998G>A; p.L666L; 15:39589876-39589876	central_nervous_system; brain	glioma	Substitution - coding silent
c.1290G>A; p.K430K; 15:39587516-39587516	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2947G>T; p.G983C; 15:39593179-39593179	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.945T>A; p.P315P; 15:39584341-39584341	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.995C>T; p.T332I; 15:39584391-39584391	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1434G>A; p.A478A; 15:39588181-39588181	breast	carcinoma	Substitution - coding silent
c.3057C>T; p.D1019D; 15:39593458-39593458	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1120+1G>A; p.?; 15:39585564-39585564	stomach	carcinoma; adenocarcinoma	Unknown
c.3057C>T; p.D1019D; 15:39593458-39593458	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3406G>T; p.G1136*; 15:39594341-39594341	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1250C>A; p.S417*; 15:39587476-39587476	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.8T>C; p.L3P; 15:39581865-39581865	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.508_509GA>TT; p.D170F; 15:39582633-39582634	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1518C>A; p.V506V; 15:39588572-39588572	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1250C>T; p.S417L; 15:39587476-39587476	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.1354G>A; p.G452S; 15:39588101-39588101	skin	malignant_melanoma	Substitution - Missense
c.1502G>A; p.W501*; 15:39588556-39588556	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3124C>T; p.Q1042*; 15:39593525-39593525	breast	carcinoma	Substitution - Nonsense
c.17G>T; p.G6V; 15:39581874-39581874	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1459G>C; p.D487H; 15:39588206-39588206	skin	malignant_melanoma	Substitution - Missense
c.663C>T; p.T221T; 15:39583652-39583652	skin	malignant_melanoma	Substitution - coding silent
c.1096G>A; p.G366R; 15:39585539-39585539	skin	malignant_melanoma	Substitution - Missense
c.544C>T; p.P182S; 15:39582669-39582669	skin	malignant_melanoma	Substitution - Missense
c.2901C>A; p.P967P; 15:39593133-39593133	skin	malignant_melanoma	Substitution - coding silent
c.1549C>T; p.R517C; 15:39588603-39588603	skin; scalp	malignant_melanoma	Substitution - Missense
c.1980C>T; p.N660N; 15:39589858-39589858	skin	malignant_melanoma	Substitution - coding silent
c.2043C>T; p.G681G; 15:39589921-39589921	skin	malignant_melanoma	Substitution - coding silent
c.2938C>T; p.R980C; 15:39593170-39593170	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.2043C>T; p.G681G; 15:39589921-39589921	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.895C>T; p.R299C; 15:39584179-39584179	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1659C>T; p.S553S; 15:39588972-39588972	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1314G>A; p.W438*; 15:39588061-39588061	skin	malignant_melanoma	Substitution - Nonsense
c.137G>A; p.R46H; 15:39582262-39582262	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1314G>A; p.W438*; 15:39588061-39588061	skin	malignant_melanoma	Substitution - Nonsense
c.2319C>T; p.R773R; 15:39591256-39591256	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3159G>C; p.T1053T; 15:39593560-39593560	ovary	other; neoplasm	Substitution - coding silent
c.1126G>A; p.D376N; 15:39587352-39587352	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2737G>A; p.V913M; 15:39592772-39592772	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3182T>C; p.L1061P; 15:39593583-39593583	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1773G>A; p.E591E; 15:39589086-39589086	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.268C>T; p.L90F; 15:39582393-39582393	skin	malignant_melanoma	Substitution - Missense
c.1811G>A; p.G604E; 15:39589239-39589239	skin	malignant_melanoma	Substitution - Missense
c.2431G>A; p.D811N; 15:39591522-39591522	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.540C>T; p.D180D; 15:39582665-39582665	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.540C>T; p.D180D; 15:39582665-39582665	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.540C>T; p.D180D; 15:39582665-39582665	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3365+5G>T; p.?; 15:39594201-39594201	liver	carcinoma	Unknown
c.540C>T; p.D180D; 15:39582665-39582665	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1094A>G; p.D365G; 15:39585537-39585537	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1138G>A; p.D380N; 15:39587364-39587364	skin	malignant_melanoma	Substitution - Missense
c.1219G>A; p.D407N; 15:39587445-39587445	skin	malignant_melanoma	Substitution - Missense
c.1219G>A; p.D407N; 15:39587445-39587445	skin; scalp	malignant_melanoma	Substitution - Missense
c.3087C>T; p.Y1029Y; 15:39593488-39593488	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1953G>T; p.T651T; 15:39589831-39589831	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1628A>C; p.K543T; 15:39588682-39588682	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3315C>T; p.F1105F; 15:39594146-39594146	skin	malignant_melanoma	Substitution - coding silent
c.1218C>T; p.C406C; 15:39587444-39587444	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.940C>T; p.R314W; 15:39584336-39584336	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1590C>T; p.D530D; 15:39588644-39588644	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2173G>T; p.G725W; 15:39590543-39590543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1406T>A; p.M469K; 15:39588153-39588153	thyroid	other; neoplasm	Substitution - Missense
c.556G>A; p.V186I; 15:39582681-39582681	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.556G>A; p.V186I; 15:39582681-39582681	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2288A>G; p.Y763C; 15:39591225-39591225	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1436G>A; p.R479Q; 15:39588183-39588183	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2223C>T; p.D741D; 15:39590593-39590593	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.155C>T; p.P52L; 15:39582280-39582280	skin	malignant_melanoma	Substitution - Missense
c.1543C>T; p.R515C; 15:39588597-39588597	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.938G>T; p.R313M; 15:39584334-39584334	liver	carcinoma	Substitution - Missense
c.1675G>T; p.G559C; 15:39588988-39588988	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2907G>A; p.G969G; 15:39593139-39593139	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1762G>T; p.D588Y; 15:39589075-39589075	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.242C>A; p.A81D; 15:39582367-39582367	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1647T>C; p.D549D; 15:39588960-39588960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3170G>A; p.G1057E; 15:39593571-39593571	skin	malignant_melanoma	Substitution - Missense
c.279C>T; p.S93S; 15:39582404-39582404	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.326G>T; p.R109L; 15:39582451-39582451	pancreas	other; adenoma	Substitution - Missense
c.1058G>A; p.C353Y; 15:39585501-39585501	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3406G>A; p.G1136R; 15:39594341-39594341	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.506T>C; p.I169T; 15:39582631-39582631	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2115C>T; p.C705C; 15:39589993-39589993	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1471+3A>G; p.?; 15:39588221-39588221	pancreas	carcinoma	Unknown
c.2921A>G; p.D974G; 15:39593153-39593153	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.11C>G; p.A4G; 15:39581868-39581868	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1557_1559delCAA; p.N521delN; 15:39588611-39588613	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - In frame
c.2232T>A; p.N744K; 15:39590602-39590602	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.610G>A; p.V204I; 15:39582735-39582735	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1193G>A; p.G398E; 15:39587419-39587419	liver	carcinoma	Substitution - Missense
c.3137C>T; p.S1046F; 15:39593538-39593538	skin	malignant_melanoma	Substitution - Missense
c.2099A>G; p.N700S; 15:39589977-39589977	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2099A>G; p.N700S; 15:39589977-39589977	breast	carcinoma	Substitution - Missense
c.2099A>G; p.N700S; 15:39589977-39589977	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2136C>A; p.H712Q; 15:39590014-39590014	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3120G>A; p.W1040*; 15:39593521-39593521	skin	malignant_melanoma	Substitution - Nonsense
c.2872C>T; p.R958C; 15:39593104-39593104	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.111C>T; p.T37T; 15:39582236-39582236	breast	carcinoma	Substitution - coding silent
c.1898G>A; p.G633D; 15:39589326-39589326	skin; mucosal	malignant_melanoma	Substitution - Missense
c.303G>A; p.R101R; 15:39582428-39582428	skin	malignant_melanoma	Substitution - coding silent
c.1202A>G; p.Q401R; 15:39587428-39587428	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2134C>T; p.H712Y; 15:39590012-39590012	skin	malignant_melanoma	Substitution - Missense
c.190G>A; p.A64T; 15:39582315-39582315	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2429G>A; p.R810Q; 15:39591520-39591520	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3101G>A; p.R1034H; 15:39593502-39593502	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.190G>A; p.A64T; 15:39582315-39582315	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.3101G>A; p.R1034H; 15:39593502-39593502	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1257G>C; p.Q419H; 15:39587483-39587483	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation