| Gene ID | 7033 |
| Symbol | TFF3 |
| Synonymous | ITF|P1B|TFI |
| Full name | trefoil factor 3 (intestinal) |
| Gene description | polypeptide P1.B|trefoil factor 3 |
| Cytoband | 21q22.3 |
| Gene type | protein-coding |
| Synonymous | MIM:600633; HGNC:HGNC:11757; Ensembl:ENSG00000160180; HPRD:02797; Vega:OTTHUMG00000086798 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.189G>A; p.L63L; 21:42315336-42315336 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.233-10T>C; p.?; 21:42313641-42313641 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Unknown |
c.46C>T; p.P16S; 21:42315479-42315479 |
cervix | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.268G>A; p.V90M; 21:42313596-42313596 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.37G>C; p.E13Q; 21:42315488-42315488 |
upper_aerodigestive_tract; larynx | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.342T>C; p.P114P; 21:42313522-42313522 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.110T>A; p.M37K; 21:42315415-42315415 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | Substitution - Missense |
c.372G>A; p.Q124Q; 21:42313492-42313492 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.376G>A; p.A126T; 21:42313488-42313488 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.31A>T; p.R11W; 21:42315494-42315494 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.276C>T; p.C92C; 21:42313588-42313588 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; plasma_cell_myeloma | Substitution - coding silent |
c.384C>T; p.C128C; 21:42312265-42312265 |
skin; upper_back | malignant_melanoma | Substitution - coding silent |
c.304T>G; p.C102G; 21:42313560-42313560 |
prostate | carcinoma | Substitution - Missense |
c.380-1G>T; p.?; 21:42312270-42312270 |
endometrium | carcinoma; endometrioid_carcinoma | Unknown |