Cancer metastasis database

Annotation category 5

Gene information

Gene ID 7001
Symbol

PRDX2

Synonymous

HEL-S-2a|NKEF-B|NKEFB|PRP|PRX2|PRXII|PTX1|TDPX1|TPX1|TSA

Full name

peroxiredoxin 2

Gene description

epididymis secretory sperm binding protein Li 2a|natural killer cell-enhancing factor B|peroxiredoxin-2|thiol-specific antioxidant 1|thioredoxin peroxidase 1|thioredoxin-dependent peroxide reductase 1|torin

Cytoband

19p13.2

Gene type

protein-coding

Synonymous

MIM:600538; HGNC:HGNC:9353; Ensembl:ENSG00000167815; HPRD:02763; Vega:OTTHUMG00000134285

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.266C>T; p.T89I; 19:12800291-12800291

 skinmalignant_melanomaSubstitution - Missense

c.103G>A; p.G35R; 19:12801159-12801159

 skinmalignant_melanomaSubstitution - Missense

c.238C>T; p.Q80*; 19:12800935-12800935

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.133C>G; p.L45V; 19:12801040-12801040

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.272G>A; p.R91Q; 19:12800285-12800285

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.227C>T; p.S76L; 19:12800946-12800946

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.520G>A; p.A174T; 19:12797158-12797158

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.479A>G; p.Q160R; 19:12799891-12799891

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.265_266insC; p.R91fs*16; 19:12800291-12800292

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeInsertion - Frameshift

c.546G>A; p.T182T; 19:12797132-12797132

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.165C>A; p.I55I; 19:12801008-12801008

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.545C>T; p.T182M; 19:12797133-12797133

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.332T>C; p.L111S; 19:12800225-12800225

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeSubstitution - Missense

c.153C>T; p.C51C; 19:12801020-12801020

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.281G>A; p.G94E; 19:12800276-12800276

 skinmalignant_melanomaSubstitution - Missense

c.348C>T; p.G116G; 19:12800209-12800209

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.328C>T; p.R110C; 19:12800229-12800229

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.319G>A; p.V107M; 19:12800238-12800238

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.253G>A; p.A85T; 19:12800920-12800920

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeSubstitution - Missense

c.236C>T; p.S79F; 19:12800937-12800937

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.396C>T; p.I132I; 19:12799974-12799974

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.146T>G; p.F49C; 19:12801027-12801027

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.355A>G; p.K119E; 19:12800202-12800202

 livercarcinomaSubstitution - Missense

c.355A>G; p.K119E; 19:12800202-12800202

 livercarcinomaSubstitution - Missense

c.498C>T; p.D166D; 19:12799872-12799872

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.77A>T; p.K26I; 19:12801185-12801185

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.165C>T; p.I55I; 19:12801008-12801008

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.559G>A; p.V187M; 19:12797119-12797119

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.397G>T; p.D133Y; 19:12799973-12799973

 prostatecarcinomaSubstitution - Missense

c.544A>T; p.T182S; 19:12797134-12797134

 breastcarcinomaSubstitution - Missense

c.475G>T; p.V159F; 19:12799895-12799895

 livercarcinomaSubstitution - Missense

c.511+1G>C; p.?; 19:12799858-12799858

 ovaryother; neoplasmUnknown

c.38C>T; p.P13L; 19:12801224-12801224

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.354G>T; p.L118L; 19:12800203-12800203

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.203T>C; p.L68P; 19:12800970-12800970

 stomachcarcinoma; adenocarcinomaSubstitution - Missense