Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6915
Symbol

TBXA2R

Synonymous

BDPLT13|TXA2-R

Full name

thromboxane A2 receptor

Gene description

prostanoid TP receptor

Cytoband

19p13.3

Gene type

protein-coding

Synonymous

MIM:188070; HGNC:HGNC:11608; Ensembl:ENSG00000006638; HPRD:01768; Vega:OTTHUMG00000180806

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.666G>T; p.L222L; 19:3599969-3599969

 thyroidother; neoplasmSubstitution - coding silent

c.994C>T; p.L332F; 19:3595726-3595726

 skinmalignant_melanomaSubstitution - Missense

c.628C>A; p.L210M; 19:3600007-3600007

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.280G>A; p.E94K; 19:3600355-3600355

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.68G>A; p.R23Q; 19:3600567-3600567

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.473C>T; p.A158V; 19:3600162-3600162

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.567C>T; p.A189A; 19:3600068-3600068

 skinmalignant_melanomaSubstitution - coding silent

c.924T>C; p.Y308Y; 19:3595796-3595796

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.924T>C; p.Y308Y; 19:3595796-3595796

 thyroidother; neoplasmSubstitution - coding silent

c.924T>C; p.Y308Y; 19:3595796-3595796

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - coding silent

c.906C>T; p.I302I; 19:3595814-3595814

 skinmalignant_melanomaSubstitution - coding silent

c.157C>T; p.R53W; 19:3600478-3600478

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1010C>T; p.T337M; 19:3595710-3595710

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.936C>T; p.R312R; 19:3595784-3595784

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.138G>C; p.L46L; 19:3600497-3600497

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.253G>A; p.V85M; 19:3600382-3600382

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.795C>T; p.I265I; 19:3595925-3595925

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.977G>A; p.R326Q; 19:3595743-3595743

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.141C>G; p.S47R; 19:3600494-3600494

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.210C>T; p.L70L; 19:3600425-3600425

 skinmalignant_melanomaSubstitution - coding silent

c.261C>T; p.S87S; 19:3600374-3600374

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.37C>T; p.R13W; 19:3600598-3600598

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.279C>T; p.F93F; 19:3600356-3600356

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.279C>T; p.F93F; 19:3600356-3600356

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.199C>T; p.L67F; 19:3600436-3600436

 skinmalignant_melanomaSubstitution - Missense

c.36C>T; p.F12F; 19:3600599-3600599

 skinmalignant_melanomaSubstitution - coding silent

c.90C>T; p.F30F; 19:3600545-3600545

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.423G>A; p.P141P; 19:3600212-3600212

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.21C>T; p.S7S; 19:3600614-3600614

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.29C>T; p.P10L; 19:3600606-3600606

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.171G>A; p.S57S; 19:3600464-3600464

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.787-1G>A; p.?; 19:3595934-3595934

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.72G>A; p.L24L; 19:3600563-3600563

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.204C>T; p.C68C; 19:3600431-3600431

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.440G>A; p.R147H; 19:3600195-3600195

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.306C>T; p.C102C; 19:3600329-3600329

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.102C>T; p.F34F; 19:3600533-3600533

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.636C>T; p.F212F; 19:3599999-3599999

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.564C>T; p.G188G; 19:3600071-3600071

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.112G>A; p.G38S; 19:3600523-3600523

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.176C>T; p.T59M; 19:3600459-3600459

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.330C>T; p.V110V; 19:3600305-3600305

 skinmalignant_melanomaSubstitution - coding silent

c.330C>T; p.V110V; 19:3600305-3600305

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.494T>C; p.L165P; 19:3600141-3600141

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.416C>T; p.S139L; 19:3600219-3600219

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940G>T; p.A314S; 19:3595780-3595780

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.885C>T; p.R295R; 19:3595835-3595835

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.155C>T; p.A52V; 19:3600480-3600480

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.373G>A; p.A125T; 19:3600262-3600262

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.230G>A; p.G77E; 19:3600405-3600405

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.113G>A; p.G38D; 19:3600522-3600522

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.625G>A; p.G209R; 19:3600010-3600010

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.284G>C; p.W95S; 19:3600351-3600351

 livercarcinomaSubstitution - Missense

c.285G>A; p.W95*; 19:3600350-3600350

 prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.855_856CA>TG; p.T286A; 19:3595864-3595865

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.568G>A; p.E190K; 19:3600067-3600067

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.218C>A; p.T73N; 19:3600417-3600417

 pancreascarcinomaSubstitution - Missense

c.71T>C; p.L24P; 19:3600564-3600564

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.270C>T; p.A90A; 19:3600365-3600365

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.168T>G; p.G56G; 19:3600467-3600467

 central_nervous_system; braingliomaSubstitution - coding silent

c.44C>A; p.T15K; 19:3600591-3600591

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.91G>A; p.A31T; 19:3600544-3600544

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.553C>T; p.L185L; 19:3600082-3600082

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.673G>A; p.V225I; 19:3599962-3599962

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.862A>T; p.K288*; 19:3595858-3595858

 ovaryother; neoplasmSubstitution - Nonsense

c.862A>T; p.K288*; 19:3595858-3595858

 ovaryother; neoplasmSubstitution - Nonsense

c.289G>A; p.A97T; 19:3600346-3600346

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.430G>A; p.A144T; 19:3600205-3600205

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.314G>A; p.C105Y; 19:3600321-3600321

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.699G>A; p.Q233Q; 19:3599936-3599936

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.398G>A; p.G133D; 19:3600237-3600237

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.153C>T; p.G51G; 19:3600482-3600482

 thyroidcarcinomaSubstitution - coding silent

c.602C>T; p.S201F; 19:3600033-3600033

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.503T>A; p.L168Q; 19:3600132-3600132

 skinmalignant_melanomaSubstitution - Missense

c.830G>T; p.S277I; 19:3595890-3595890

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.164G>A; p.G55E; 19:3600471-3600471

 skinmalignant_melanomaSubstitution - Missense

c.435G>A; p.S145S; 19:3600200-3600200

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.420C>T; p.R140R; 19:3600215-3600215

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent