Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6855
Symbol

SYP

Synonymous

MRX96|MRXSYP

Full name

synaptophysin

Gene description

major synaptic vesicle protein P38

Cytoband

Xp11.23-p11.22

Gene type

protein-coding

Synonymous

MIM:313475; HGNC:HGNC:11506; Ensembl:ENSG00000102003; HPRD:02435; Vega:OTTHUMG00000034557

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.289G>A; p.V97I; 23:49194300-49194300

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.289G>A; p.V97I; 23:49194300-49194300

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.412G>T; p.G138W; 23:49194177-49194177

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.7C>A; p.L3M; 23:49200180-49200180

 livercarcinomaSubstitution - Missense

c.7C>A; p.L3M; 23:49200180-49200180

 livercarcinomaSubstitution - Missense

c.879C>T; p.G293G; 23:49191500-49191500

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.883T>C; p.Y295H; 23:49191496-49191496

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.482C>T; p.A161V; 23:49193405-49193405

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.437C>T; p.T146M; 23:49193450-49193450

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.332C>T; p.A111V; 23:49194257-49194257

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.693G>A; p.P231P; 23:49191686-49191686

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.553C>T; p.Q185*; 23:49193334-49193334

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.554A>G; p.Q185R; 23:49193333-49193333

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.69G>A; p.K23K; 23:49199001-49199001

 breastcarcinomaSubstitution - coding silent

c.554A>G; p.Q185R; 23:49193333-49193333

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.719C>A; p.P240H; 23:49191660-49191660

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.201C>T; p.I67I; 23:49197741-49197741

 pancreasNSSubstitution - coding silent

c.201C>T; p.I67I; 23:49197741-49197741

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.582A>G; p.R194R; 23:49193305-49193305

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.551G>A; p.R184H; 23:49193336-49193336

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.863G>A; p.G288D; 23:49191516-49191516

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.47G>T; p.G16V; 23:49199023-49199023

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.919A>T; p.T307S; 23:49191460-49191460

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.143G>T; p.S48I; 23:49197799-49197799

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.318C>T; p.F106F; 23:49194271-49194271

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.416C>A; p.P139H; 23:49194173-49194173

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.664G>A; p.V222M; 23:49191715-49191715

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.664G>A; p.V222M; 23:49191715-49191715

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.312C>T; p.A104A; 23:49194277-49194277

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.302C>A; p.S101Y; 23:49194287-49194287

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.648C>T; p.V216V; 23:49191731-49191731

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.164T>G; p.V55G; 23:49197778-49197778

 skinmalignant_melanomaSubstitution - Missense

c.745G>A; p.A249T; 23:49191634-49191634

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.398G>A; p.R133Q; 23:49194191-49194191

 breastcarcinomaSubstitution - Missense

c.583G>T; p.D195Y; 23:49193304-49193304

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.257C>G; p.T86S; 23:49194332-49194332

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.108C>T; p.F36F; 23:49197834-49197834

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.108C>T; p.F36F; 23:49197834-49197834

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.489G>A; p.G163G; 23:49193398-49193398

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.786C>T; p.Y262Y; 23:49191593-49191593

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.555G>C; p.Q185H; 23:49193332-49193332

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.133G>A; p.G45S; 23:49197809-49197809

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.133G>A; p.G45S; 23:49197809-49197809

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.448G>A; p.A150T; 23:49193439-49193439

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.41T>C; p.V14A; 23:49199029-49199029

 breastcarcinomaSubstitution - Missense

c.913G>A; p.A305T; 23:49191466-49191466

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.402G>A; p.E134E; 23:49194187-49194187

 NSNSSubstitution - coding silent

c.213C>T; p.F71F; 23:49197729-49197729

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.909G>C; p.Q303H; 23:49191470-49191470

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.746C>T; p.A249V; 23:49191633-49191633

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.184G>A; p.E62K; 23:49197758-49197758

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.816C>T; p.G272G; 23:49191563-49191563

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.189T>C; p.S63S; 23:49197753-49197753

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent