lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6817
Symbol	SULT1A1
Synonymous	HAST1/HAST2\|P-PST\|PST\|ST1A1\|ST1A3\|STP\|STP1\|TSPST1
Full name	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
Gene description	P-PST 1\|aryl sulfotransferase 1\|phenol-sulfating phenol sulfotransferase 1\|sulfotransferase 1A1\|thermostable phenol sulfotransferase1\|ts-PST
Cytoband	16p12.1
Gene type	protein-coding
Synonymous	MIM:171150; HGNC:HGNC:11453; Ensembl:ENSG00000196502; HPRD:01372; Vega:OTTHUMG00000131765

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.318G>A; p.K106K; 16:28608345-28608345	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.52G>C; p.V18L; 16:28608804-28608804	skin	malignant_melanoma	Substitution - Missense
c.56C>T; p.P19L; 16:28608800-28608800	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.56C>T; p.P19L; 16:28608800-28608800	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.56C>T; p.P19L; 16:28608800-28608800	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.220C>T; p.P74S; 16:28608532-28608532	oesophagus	carcinoma	Substitution - Missense
c.549C>T; p.S183S; 16:28606806-28606806	skin	malignant_melanoma	Substitution - coding silent
c.394G>A; p.A132T; 16:28607056-28607056	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.394G>A; p.A132T; 16:28607056-28607056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.293A>G; p.D98G; 16:28608370-28608370	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.232C>T; p.R78W; 16:28608520-28608520	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.303C>T; p.A101A; 16:28608360-28608360	skin	malignant_melanoma	Substitution - coding silent
c.232C>T; p.R78W; 16:28608520-28608520	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.231G>A; p.M77I; 16:28608521-28608521	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.841G>A; p.A281T; 16:28605868-28605868	urinary_tract; bladder	carcinoma	Substitution - Missense
c.400G>A; p.D134N; 16:28607050-28607050	skin	malignant_melanoma	Substitution - Missense
c.327G>T; p.L109L; 16:28608336-28608336	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.29C>T; p.P10L; 16:28608827-28608827	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.29C>T; p.P10L; 16:28608827-28608827	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.486C>T; p.F162F; 16:28606964-28606964	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.727G>A; p.V243I; 16:28606104-28606104	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.465G>T; p.W155C; 16:28606985-28606985	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.727G>A; p.V243I; 16:28606104-28606104	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.84G>C; p.L28L; 16:28608772-28608772	skin	malignant_melanoma	Substitution - coding silent
c.358G>A; p.D120N; 16:28608305-28608305	skin	malignant_melanoma	Substitution - Missense
c.449C>A; p.P150H; 16:28607001-28607001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.126C>A; p.L42L; 16:28608730-28608730	skin	malignant_melanoma	Substitution - coding silent
c.228C>T; p.F76F; 16:28608524-28608524	skin	malignant_melanoma	Substitution - coding silent
c.492C>T; p.V164V; 16:28606958-28606958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.492C>T; p.V164V; 16:28606958-28606958	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.162A>G; p.V54V; 16:28608590-28608590	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.592G>A; p.E198K; 16:28606763-28606763	skin	malignant_melanoma	Substitution - Missense
c.761C>T; p.P254L; 16:28606070-28606070	skin	malignant_melanoma	Substitution - Missense
c.155C>T; p.T52I; 16:28608597-28608597	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.607G>C; p.E203Q; 16:28606224-28606224	urinary_tract; bladder	carcinoma	Substitution - Missense
c.696G>A; p.M232I; 16:28606135-28606135	skin	malignant_melanoma	Substitution - Missense
c.634G>A; p.G212R; 16:28606197-28606197	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.641C>T; p.S214F; 16:28606190-28606190	skin	malignant_melanoma	Substitution - Missense
c.641C>T; p.S214F; 16:28606190-28606190	skin	malignant_melanoma	Substitution - Missense
c.11T>C; p.I4T; 16:28608845-28608845	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.739T>C; p.F247L; 16:28606092-28606092	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.739T>C; p.F247L; 16:28606092-28606092	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.739T>C; p.F247L; 16:28606092-28606092	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.739T>C; p.F247L; 16:28606092-28606092	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.468C>A; p.D156E; 16:28606982-28606982	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.739T>C; p.F247L; 16:28606092-28606092	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.744G>A; p.M248I; 16:28606087-28606087	bone; pelvis	chondrosarcoma	Substitution - Missense
c.734_735insC; p.Q245fs*30; 16:28606096-28606097	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.491T>C; p.V164A; 16:28606959-28606959	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.214C>T; p.R72*; 16:28608538-28608538	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.268C>T; p.P90S; 16:28608484-28608484	skin	malignant_melanoma	Substitution - Missense
c.252C>T; p.F84F; 16:28608500-28608500	skin	malignant_melanoma	Substitution - coding silent
c.541G>A; p.E181K; 16:28606814-28606814	skin	malignant_melanoma	Substitution - Missense
c.302C>G; p.A101G; 16:28608361-28608361	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.151A>T; p.T51S; 16:28608601-28608601	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.57G>A; p.P19P; 16:28608799-28608799	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.57G>A; p.P19P; 16:28608799-28608799	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.185A>G; p.Y62C; 16:28608567-28608567	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.49G>A; p.G17R; 16:28608807-28608807	skin	malignant_melanoma	Substitution - Missense
c.272C>G; p.S91*; 16:28608480-28608480	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.178A>T; p.M60L; 16:28608574-28608574	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.494G>A; p.G165E; 16:28606956-28606956	skin	malignant_melanoma	Substitution - Missense
c.60C>T; p.L20L; 16:28608796-28608796	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.494G>A; p.G165E; 16:28606956-28606956	skin	malignant_melanoma	Substitution - Missense
c.194G>A; p.G65D; 16:28608558-28608558	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.299C>T; p.P100L; 16:28608364-28608364	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.413C>T; p.S138F; 16:28607037-28607037	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.388C>T; p.R130C; 16:28607062-28607062	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.30G>A; p.P10P; 16:28608826-28608826	thyroid	carcinoma	Substitution - coding silent
c.878C>T; p.S293F; 16:28605831-28605831	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.153T>C; p.T51T; 16:28608599-28608599	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.319A>G; p.T107A; 16:28608344-28608344	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.298C>G; p.P100A; 16:28608365-28608365	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.843G>A; p.A281A; 16:28605866-28605866	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.308G>A; p.R103Q; 16:28608355-28608355	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.699G>C; p.K233N; 16:28606132-28606132	breast	carcinoma	Substitution - Missense
c.642C>T; p.S214S; 16:28606189-28606189	skin	malignant_melanoma	Substitution - coding silent
c.645G>A; p.L215L; 16:28606186-28606186	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.645G>A; p.L215L; 16:28606186-28606186	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.42C>T; p.Y14Y; 16:28608814-28608814	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.372+10G>T; p.?; 16:28608281-28608281	liver	carcinoma	Unknown
c.680C>T; p.T227M; 16:28606151-28606151	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.532G>T; p.E178*; 16:28606823-28606823	skin; mucosal	malignant_melanoma	Substitution - Nonsense
c.513C>T; p.S171S; 16:28606842-28606842	skin	malignant_melanoma	Substitution - coding silent
c.204G>A; p.E68E; 16:28608548-28608548	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.600G>C; p.P200P; 16:28606231-28606231	kidney	other; neoplasm	Substitution - coding silent
c.600G>C; p.P200P; 16:28606231-28606231	breast	carcinoma	Substitution - coding silent
c.12C>T; p.I4I; 16:28608844-28608844	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.600G>C; p.P200P; 16:28606231-28606231	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.600G>C; p.P200P; 16:28606231-28606231	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation