lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6781
Symbol	STC1
Synonymous	STC
Full name	stanniocalcin 1
Gene description	stanniocalcin-1
Cytoband	8p21.2
Gene type	protein-coding
Synonymous	MIM:601185; HGNC:HGNC:11373; Ensembl:ENSG00000159167; HPRD:03115; Vega:OTTHUMG00000097853

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.643C>T; p.R215C; 8:23844871-23844871	pancreas	carcinoma	Substitution - Missense
c.643C>T; p.R215C; 8:23844871-23844871	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.202G>A; p.D68N; 8:23852301-23852301	skin	malignant_melanoma	Substitution - Missense
c.202G>A; p.D68N; 8:23852301-23852301	skin	malignant_melanoma	Substitution - Missense
c.221G>T; p.C74F; 8:23852282-23852282	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.298G>A; p.A100T; 8:23851495-23851495	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.241G>A; p.A81T; 8:23852262-23852262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.241G>A; p.A81T; 8:23852262-23852262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.368A>G; p.E123G; 8:23851425-23851425	breast	carcinoma	Substitution - Missense
c.157G>T; p.G53C; 8:23852346-23852346	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.603C>A; p.H201Q; 8:23844911-23844911	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.599A>G; p.D200G; 8:23844915-23844915	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.485G>T; p.R162I; 8:23845029-23845029	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.274G>A; p.V92I; 8:23851519-23851519	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.303C>T; p.N101N; 8:23851490-23851490	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.304G>A; p.G102R; 8:23851489-23851489	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.304G>A; p.G102R; 8:23851489-23851489	skin	malignant_melanoma	Substitution - Missense
c.508T>C; p.C170R; 8:23845006-23845006	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.688C>G; p.R230G; 8:23844826-23844826	skin; hand	malignant_melanoma	Substitution - Missense
c.189C>T; p.S63S; 8:23852314-23852314	skin; neck	malignant_melanoma	Substitution - coding silent
c.570G>A; p.M190I; 8:23844944-23844944	skin	malignant_melanoma	Substitution - Missense
c.216C>T; p.D72D; 8:23852287-23852287	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.376G>A; p.E126K; 8:23851417-23851417	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.688C>A; p.R230R; 8:23844826-23844826	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.199A>G; p.T67A; 8:23852304-23852304	pancreas	carcinoma	Substitution - Missense
c.261+1G>A; p.?; 8:23852241-23852241	breast	carcinoma	Unknown
c.351C>T; p.F117F; 8:23851442-23851442	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.318G>T; p.K106N; 8:23851475-23851475	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.282G>T; p.E94D; 8:23851511-23851511	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.321C>T; p.V107V; 8:23851472-23851472	liver	carcinoma	Substitution - coding silent
c.321C>T; p.V107V; 8:23851472-23851472	liver	carcinoma	Substitution - coding silent
c.307G>T; p.V103F; 8:23851486-23851486	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.635A>G; p.N212S; 8:23844879-23844879	prostate	carcinoma	Substitution - Missense
c.308T>A; p.V103D; 8:23851485-23851485	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.335G>A; p.R112Q; 8:23851458-23851458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.206G>A; p.G69E; 8:23852297-23852297	skin	malignant_melanoma	Substitution - Missense
c.121G>C; p.E41Q; 8:23852382-23852382	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.490G>C; p.V164L; 8:23845024-23845024	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.106G>A; p.A36T; 8:23854418-23854418	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.90G>A; p.R30R; 8:23854434-23854434	skin	malignant_melanoma	Substitution - coding silent
c.90G>A; p.R30R; 8:23854434-23854434	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.602A>T; p.H201L; 8:23844912-23844912	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.180G>T; p.L60L; 8:23852323-23852323	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.299C>T; p.A100V; 8:23851494-23851494	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.98G>A; p.R33Q; 8:23854426-23854426	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.131G>A; p.R44H; 8:23852372-23852372	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.411C>T; p.I137I; 8:23851382-23851382	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.356G>T; p.R119M; 8:23851437-23851437	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.722G>A; p.R241H; 8:23844792-23844792	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.722G>A; p.R241H; 8:23844792-23844792	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.181G>A; p.E61K; 8:23852322-23852322	skin	malignant_melanoma	Substitution - Missense
c.700G>A; p.D234N; 8:23844814-23844814	skin	malignant_melanoma	Substitution - Missense
c.116C>T; p.S39L; 8:23854408-23854408	skin	malignant_melanoma	Substitution - Missense
c.445G>A; p.V149I; 8:23851348-23851348	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.445G>A; p.V149I; 8:23851348-23851348	haematopoietic_and_lymphoid_tissue; spleen	lymphoid_neoplasm; marginal_zone_lymphoma	Substitution - Missense
c.623G>A; p.R208Q; 8:23844891-23844891	skin	malignant_melanoma	Substitution - Missense
c.235T>C; p.Y79H; 8:23852268-23852268	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.656C>T; p.P219L; 8:23844858-23844858	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.675C>T; p.L225L; 8:23844839-23844839	skin	malignant_melanoma	Substitution - coding silent
c.575G>T; p.S192I; 8:23844939-23844939	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.327C>T; p.L109L; 8:23851466-23851466	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.327C>T; p.L109L; 8:23851466-23851466	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.273C>T; p.F91F; 8:23851520-23851520	skin	malignant_melanoma	Substitution - coding silent
c.75C>T; p.D25D; 8:23854449-23854449	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.163G>A; p.G55R; 8:23852340-23852340	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.156C>T; p.V52V; 8:23852347-23852347	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.420G>A; p.R140R; 8:23851373-23851373	skin	malignant_melanoma	Substitution - coding silent
c.419G>A; p.R140Q; 8:23851374-23851374	skin	malignant_melanoma	Substitution - Missense
c.96C>A; p.S32S; 8:23854428-23854428	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.205G>A; p.G69R; 8:23852298-23852298	skin	malignant_melanoma	Substitution - Missense
c.577C>T; p.L193F; 8:23844937-23844937	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.444C>A; p.V148V; 8:23851349-23851349	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.501G>A; p.L167L; 8:23845013-23845013	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.281A>G; p.E94G; 8:23851512-23851512	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.721C>T; p.R241C; 8:23844793-23844793	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.441G>C; p.E147D; 8:23851352-23851352	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.328G>A; p.A110T; 8:23851465-23851465	stomach	adenocarcinoma	Substitution - Missense
c.356G>A; p.R119K; 8:23851437-23851437	skin; mucosal	malignant_melanoma	Substitution - Missense
c.236A>G; p.Y79C; 8:23852267-23852267	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.706C>T; p.P236S; 8:23844808-23844808	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.263G>T; p.G88V; 8:23851530-23851530	urinary_tract; bladder	carcinoma	Substitution - Missense
c.119-2A>T; p.?; 8:23852386-23852386	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Unknown
c.119-2A>T; p.?; 8:23852386-23852386	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Unknown
c.130C>T; p.R44C; 8:23852373-23852373	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.280G>C; p.E94Q; 8:23851513-23851513	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.588C>T; p.I196I; 8:23844926-23844926	skin	malignant_melanoma	Substitution - coding silent
c.180G>A; p.L60L; 8:23852323-23852323	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.180G>A; p.L60L; 8:23852323-23852323	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.582C>T; p.F194F; 8:23844932-23844932	skin	malignant_melanoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation