lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6752
Symbol	SSTR2
Synonymous	-
Full name	somatostatin receptor 2
Gene description	SRIF-1\|SS2R\|somatostatin receptor type 2
Cytoband	17q24
Gene type	protein-coding
Synonymous	MIM:182452; HGNC:HGNC:11331; HPRD:01674

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.151T>G; p.F51V; 17:73169470-73169470	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.74T>A; p.V25E; 17:73169393-73169393	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.901A>T; p.T301S; 17:73170220-73170220	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.988G>A; p.V330I; 17:73170307-73170307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.208C>T; p.R70C; 17:73169527-73169527	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.861C>T; p.T287T; 17:73170180-73170180	skin	malignant_melanoma	Substitution - coding silent
c.345C>T; p.C115C; 17:73169664-73169664	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.425T>A; p.L142Q; 17:73169744-73169744	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.147C>A; p.I49I; 17:73169466-73169466	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.541G>A; p.A181T; 17:73169860-73169860	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.327C>G; p.P109P; 17:73169646-73169646	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.979C>A; p.L327I; 17:73170298-73170298	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.838G>A; p.V280I; 17:73170157-73170157	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.672C>G; p.I224M; 17:73169991-73169991	stomach	adenocarcinoma	Substitution - Missense
c.838G>A; p.V280I; 17:73170157-73170157	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.838G>A; p.V280I; 17:73170157-73170157	skin	malignant_melanoma	Substitution - Missense
c.273C>G; p.L91L; 17:73169592-73169592	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1028G>A; p.S343N; 17:73170347-73170347	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.839T>C; p.V280A; 17:73170158-73170158	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1061C>T; p.T354M; 17:73170380-73170380	bone; pelvis	chondrosarcoma	Substitution - Missense
c.291T>A; p.P97P; 17:73169610-73169610	breast	carcinoma	Substitution - coding silent
c.1062G>A; p.T354T; 17:73170381-73170381	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.470G>T; p.R157L; 17:73169789-73169789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.265G>A; p.D89N; 17:73169584-73169584	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1046G>A; p.R349Q; 17:73170365-73170365	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1046G>A; p.R349Q; 17:73170365-73170365	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.763A>G; p.T255A; 17:73170082-73170082	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.860C>T; p.T287I; 17:73170179-73170179	skin	malignant_melanoma	Substitution - Missense
c.615C>A; p.Y205*; 17:73169934-73169934	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.107C>T; p.P36L; 17:73169426-73169426	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.557A>G; p.N186S; 17:73169876-73169876	skin	malignant_melanoma	Substitution - Missense
c.407T>A; p.M136K; 17:73169726-73169726	liver	carcinoma	Substitution - Missense
c.211T>C; p.Y71H; 17:73169530-73169530	skin	malignant_melanoma	Substitution - Missense
c.1018C>T; p.R340W; 17:73170337-73170337	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.407T>A; p.M136K; 17:73169726-73169726	liver	carcinoma	Substitution - Missense
c.661C>T; p.L221F; 17:73169980-73169980	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.376C>G; p.Q126E; 17:73169695-73169695	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.193A>G; p.I65V; 17:73169512-73169512	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.999C>A; p.S333R; 17:73170318-73170318	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.470G>A; p.R157Q; 17:73169789-73169789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.450G>A; p.S150S; 17:73169769-73169769	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.829G>A; p.V277I; 17:73170148-73170148	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.550C>T; p.R184W; 17:73169869-73169869	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1016A>T; p.E339V; 17:73170335-73170335	skin	malignant_melanoma	Substitution - Missense
c.550C>T; p.R184W; 17:73169869-73169869	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.608C>T; p.A203V; 17:73169927-73169927	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.862C>T; p.P288S; 17:73170181-73170181	skin	malignant_melanoma	Substitution - Missense
c.534G>A; p.M178I; 17:73169853-73169853	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.534G>A; p.M178I; 17:73169853-73169853	skin	malignant_melanoma	Substitution - Missense
c.152T>C; p.F51S; 17:73169471-73169471	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.460A>G; p.R154G; 17:73169779-73169779	breast	carcinoma	Substitution - Missense
c.207C>A; p.L69L; 17:73169526-73169526	skin	malignant_melanoma	Substitution - coding silent
c.509C>T; p.S170F; 17:73169828-73169828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.262G>T; p.A88S; 17:73169581-73169581	prostate	carcinoma	Substitution - Missense
c.690C>T; p.F230F; 17:73170009-73170009	skin	malignant_melanoma	Substitution - coding silent
c.837C>T; p.S279S; 17:73170156-73170156	skin	malignant_melanoma	Substitution - coding silent
c.286C>A; p.L96M; 17:73169605-73169605	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058C>G; p.T353S; 17:73170377-73170377	central_nervous_system; brain	glioma	Substitution - Missense
c.732C>T; p.S244S; 17:73170051-73170051	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.474G>A; p.T158T; 17:73169793-73169793	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.414C>T; p.I138I; 17:73169733-73169733	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.268G>C; p.E90Q; 17:73169587-73169587	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1014G>A; p.G338G; 17:73170333-73170333	skin	malignant_melanoma	Substitution - coding silent
c.674G>T; p.C225F; 17:73169993-73169993	thyroid	carcinoma	Substitution - Missense
c.998G>A; p.S333N; 17:73170317-73170317	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.727G>A; p.G243S; 17:73170046-73170046	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.473C>T; p.T158M; 17:73169792-73169792	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.639C>T; p.F213F; 17:73169958-73169958	skin	malignant_melanoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation