Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6750
Symbol

SST

Synonymous

SMST

Full name

somatostatin

Gene description

growth hormone release-inhibiting factor|prepro-somatostatin|somatostatin-14|somatostatin-28

Cytoband

3q28

Gene type

protein-coding

Synonymous

MIM:182450; HGNC:HGNC:11329; Ensembl:ENSG00000157005; HPRD:08920; Vega:OTTHUMG00000156462

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.263G>T; p.R88I; 3:187669153-187669153

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.246G>A; p.M82I; 3:187669170-187669170

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.246G>A; p.M82I; 3:187669170-187669170

 skinmalignant_melanomaSubstitution - Missense

c.302G>A; p.R101H; 3:187669114-187669114

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.302G>A; p.R101H; 3:187669114-187669114

 haematopoietic_and_lymphoid_tissue; spleenlymphoid_neoplasm; marginal_zone_lymphomaSubstitution - Missense

c.36G>A; p.A12A; 3:187670256-187670256

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.281C>T; p.P94L; 3:187669135-187669135

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.154T>G; p.F52V; 3:187669262-187669262

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.283_284GC>CA; p.A95H; 3:187669132-187669133

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.114C>T; p.S38S; 3:187670178-187670178

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.189G>A; p.T63T; 3:187669227-187669227

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.296G>A; p.R99Q; 3:187669120-187669120

 skinmalignant_melanomaSubstitution - Missense

c.295C>A; p.R99R; 3:187669121-187669121

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.150G>T; p.K50N; 3:187669266-187669266

 pleurapulmonary_blastomaSubstitution - Missense

c.27G>A; p.A9A; 3:187670265-187670265

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.27G>A; p.A9A; 3:187670265-187670265

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.13C>T; p.R5C; 3:187670279-187670279

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.13C>T; p.R5C; 3:187670279-187670279

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.13C>T; p.R5C; 3:187670279-187670279

 large_intestine; coloncarcinomaSubstitution - Missense

c.13C>T; p.R5C; 3:187670279-187670279

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.281C>A; p.P94Q; 3:187669135-187669135

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.213A>C; p.E71D; 3:187669203-187669203

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323T>A; p.F108Y; 3:187669093-187669093

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.298G>T; p.E100*; 3:187669118-187669118

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.318G>T; p.K106N; 3:187669098-187669098

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.188C>T; p.T63M; 3:187669228-187669228

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.188C>T; p.T63M; 3:187669228-187669228

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.60C>A; p.G20G; 3:187670232-187670232

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.46G>A; p.V16I; 3:187670246-187670246

 breastcarcinomaSubstitution - Missense

c.46G>A; p.V16I; 3:187670246-187670246

 pancreascarcinomaSubstitution - Missense

c.109A>T; p.K37*; 3:187670183-187670183

 skinmalignant_melanomaSubstitution - Nonsense

c.109A>T; p.K37*; 3:187670183-187670183

 skinmalignant_melanomaSubstitution - Nonsense

c.249G>A; p.R83R; 3:187669167-187669167

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.241G>A; p.E81K; 3:187669175-187669175

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.81G>A; p.S27S; 3:187670211-187670211

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.190G>A; p.E64K; 3:187669226-187669226

 skinmalignant_melanomaSubstitution - Missense

c.190G>A; p.E64K; 3:187669226-187669226

 skinmalignant_melanomaSubstitution - Missense

c.73G>A; p.A25T; 3:187670219-187670219

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.73G>A; p.A25T; 3:187670219-187670219

 pancreasNSSubstitution - Missense