Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6642
Symbol

SNX1

Synonymous

HsT17379|VPS5

Full name

sorting nexin 1

Gene description

sorting nexin 1A|sorting nexin-1

Cytoband

15q22.31

Gene type

protein-coding

Synonymous

MIM:601272; HGNC:HGNC:11172; HPRD:03171

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1294G>A; p.E432K; 15:64134736-64134736

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.807G>T; p.E269D; 15:64127806-64127806

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.553A>G; p.R185G; 15:64126121-64126121

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1283A>T; p.Q428L; 15:64134725-64134725

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.814C>T; p.R272C; 15:64129922-64129922

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.56C>T; p.P19L; 15:64096069-64096069

 ovaryother; neoplasmSubstitution - Missense

c.1147G>C; p.E383Q; 15:64131818-64131818

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.648C>T; p.L216L; 15:64126216-64126216

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.367A>C; p.N123H; 15:64118212-64118212

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.472G>T; p.G158C; 15:64123508-64123508

 pancreascarcinomaSubstitution - Missense

c.828C>A; p.T276T; 15:64129936-64129936

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.199C>G; p.P67A; 15:64112612-64112612

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.815G>A; p.R272H; 15:64129923-64129923

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1424G>A; p.R475Q; 15:64136388-64136388

 breastcarcinomaSubstitution - Missense

c.1201C>T; p.R401C; 15:64131872-64131872

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.445A>G; p.I149V; 15:64118833-64118833

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.282G>T; p.V94V; 15:64118127-64118127

 skinmalignant_melanomaSubstitution - coding silent

c.761C>T; p.T254I; 15:64127760-64127760

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.607C>G; p.Q203E; 15:64126175-64126175

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.827C>T; p.T276I; 15:64129935-64129935

 skinmalignant_melanomaSubstitution - Missense

c.192C>T; p.S64S; 15:64112605-64112605

 skinmalignant_melanomaSubstitution - coding silent

c.1376G>C; p.R459P; 15:64136340-64136340

 breastcarcinomaSubstitution - Missense

c.949G>C; p.E317Q; 15:64130255-64130255

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.914C>G; p.S305*; 15:64130022-64130022

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.291C>G; p.S97S; 15:64118136-64118136

 prostateadenomaSubstitution - coding silent

c.964C>T; p.R322C; 15:64130270-64130270

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1376G>A; p.R459Q; 15:64136340-64136340

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.585G>A; p.E195E; 15:64126153-64126153

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.734_735AC>TT; p.Y245F; 15:64127733-64127734

 skinmalignant_melanomaSubstitution - Missense

c.818C>T; p.A273V; 15:64129926-64129926

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.884T>C; p.V295A; 15:64129992-64129992

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.351T>C; p.P117P; 15:64118196-64118196

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.630delG; p.P212fs*6; 15:64126198-64126198

 livercarcinomaDeletion - Frameshift

c.291C>T; p.S97S; 15:64118136-64118136

 skinmalignant_melanomaSubstitution - coding silent

c.731+2T>C; p.?; 15:64127254-64127254

 stomachcarcinoma; adenocarcinomaUnknown

c.1256G>A; p.R419H; 15:64134698-64134698

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1087T>C; p.L363L; 15:64131758-64131758

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.419A>G; p.E140G; 15:64118807-64118807

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1220G>A; p.R407H; 15:64131891-64131891

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.206A>T; p.N69I; 15:64112619-64112619

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1051C>G; p.L351V; 15:64131722-64131722

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.597G>A; p.E199E; 15:64126165-64126165

 skinmalignant_melanomaSubstitution - coding silent

c.1288A>T; p.K430*; 15:64134730-64134730

 thyroidother; neoplasmSubstitution - Nonsense

c.1470G>T; p.K490N; 15:64136884-64136884

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.670G>A; p.V224I; 15:64127191-64127191

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.179A>C; p.K60T; 15:64112592-64112592

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.274G>A; p.A92T; 15:64118119-64118119

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.471T>C; p.D157D; 15:64123507-64123507

 breastcarcinomaSubstitution - coding silent

c.1553C>T; p.A518V; 15:64137602-64137602

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.412G>T; p.E138*; 15:64118800-64118800

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.369T>G; p.N123K; 15:64118214-64118214

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.767T>C; p.L256S; 15:64127766-64127766

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.487G>A; p.V163I; 15:64123523-64123523

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.160-1G>T; p.?; 15:64112572-64112572

 lungcarcinoma; adenocarcinomaUnknown

c.414A>G; p.E138E; 15:64118802-64118802

 skin; legmalignant_melanoma; superficial_spreadingSubstitution - coding silent

c.70G>C; p.E24Q; 15:64096083-64096083

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.965G>A; p.R322H; 15:64130271-64130271

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1188G>A; p.L396L; 15:64131859-64131859

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1401C>T; p.F467F; 15:64136365-64136365

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.864C>A; p.F288L; 15:64129972-64129972

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.489A>G; p.V163V; 15:64123525-64123525

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent