lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6640
Symbol	SNTA1
Synonymous	LQT12\|SNT1\|TACIP1\|dJ1187J4.5
Full name	syntrophin, alpha 1
Gene description	59 kDa dystrophin-associated protein A1 acidic component 1\|acidic alpha 1 syntrophin\|alpha-1-syntrophin\|dystrophin-associated protein A1, 59kDa, acidic component\|pro-TGF-alpha cytoplasmic domain-interacting protein 1\|syntrophin, alpha 1 (dystrophin-associ
Cytoband	20q11.2
Gene type	protein-coding
Synonymous	MIM:601017; HGNC:HGNC:11167; Ensembl:ENSG00000101400; HPRD:03009; Vega:OTTHUMG00000032259

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1443G>A; p.S481S; 20:33408582-33408582	large_intestine; colon	NS	Substitution - coding silent
c.520C>A; p.P174T; 20:33417900-33417900	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.610C>G; p.P204A; 20:33417810-33417810	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.420G>C; p.G140G; 20:33438917-33438917	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1008G>A; p.R336R; 20:33412328-33412328	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1014C>T; p.A338A; 20:33412322-33412322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.977C>T; p.S326F; 20:33412359-33412359	skin	malignant_melanoma	Substitution - Missense
c.711G>T; p.E237D; 20:33412773-33412773	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.630C>T; p.S210S; 20:33417790-33417790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1271C>A; p.S424Y; 20:33408855-33408855	liver	carcinoma	Substitution - Missense
c.1271C>A; p.S424Y; 20:33408855-33408855	liver	carcinoma	Substitution - Missense
c.1351G>A; p.E451K; 20:33408775-33408775	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.372C>T; p.D124D; 20:33438965-33438965	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1112G>C; p.G371A; 20:33410260-33410260	pancreas	carcinoma	Substitution - Missense
c.613A>C; p.T205P; 20:33417807-33417807	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.375G>A; p.Q125Q; 20:33438962-33438962	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.337C>G; p.L113V; 20:33439000-33439000	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1105C>T; p.R369C; 20:33410267-33410267	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1209C>T; p.A403A; 20:33410163-33410163	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1394T>C; p.F465S; 20:33408732-33408732	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1513G>T; p.A505S; 20:33408512-33408512	breast	carcinoma	Substitution - Missense
c.398A>G; p.D133G; 20:33438939-33438939	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.684C>T; p.P228P; 20:33417736-33417736	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.648C>T; p.S216S; 20:33417772-33417772	skin	malignant_melanoma	Substitution - coding silent
c.1464C>T; p.F488F; 20:33408561-33408561	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.939G>A; p.L313L; 20:33412397-33412397	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.321G>T; p.E107D; 20:33439016-33439016	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.782C>T; p.A261V; 20:33412702-33412702	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.672G>C; p.K224N; 20:33417748-33417748	pancreas	carcinoma	Substitution - Missense
c.782C>T; p.A261V; 20:33412702-33412702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1503C>G; p.L501L; 20:33408522-33408522	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1244C>T; p.T415M; 20:33408882-33408882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1203C>G; p.H401Q; 20:33410169-33410169	NS	malignant_melanoma	Substitution - Missense
c.557G>A; p.G186D; 20:33417863-33417863	skin; shoulder	malignant_melanoma	Substitution - Missense
c.853G>A; p.A285T; 20:33412631-33412631	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1361A>T; p.Q454L; 20:33408765-33408765	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1118G>A; p.R373H; 20:33410254-33410254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1118G>A; p.R373H; 20:33410254-33410254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.287G>C; p.G96A; 20:33443334-33443334	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1362G>T; p.Q454H; 20:33408764-33408764	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1032C>T; p.I344I; 20:33412304-33412304	pancreas	carcinoma	Substitution - coding silent
c.504T>C; p.Y168Y; 20:33417916-33417916	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069T>G; p.S357A; 20:33410303-33410303	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.979C>G; p.L327V; 20:33412357-33412357	urinary_tract; bladder	carcinoma	Substitution - Missense
c.672G>A; p.K224K; 20:33417748-33417748	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1180C>A; p.R394S; 20:33410192-33410192	skin	malignant_melanoma	Substitution - Missense
c.1061C>G; p.S354C; 20:33410311-33410311	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1181G>A; p.R394H; 20:33410191-33410191	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1499G>A; p.R500H; 20:33408526-33408526	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.719C>T; p.S240L; 20:33412765-33412765	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.361T>C; p.L121L; 20:33438976-33438976	thyroid	carcinoma	Substitution - coding silent
c.497-7C>T; p.?; 20:33417930-33417930	stomach	carcinoma; adenocarcinoma	Unknown
c.1147G>A; p.V383M; 20:33410225-33410225	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1147G>A; p.V383M; 20:33410225-33410225	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.617C>T; p.P206L; 20:33417803-33417803	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1392T>A; p.L464L; 20:33408734-33408734	skin	malignant_melanoma	Substitution - coding silent
c.828G>A; p.K276K; 20:33412656-33412656	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.828G>A; p.K276K; 20:33412656-33412656	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.829G>A; p.D277N; 20:33412655-33412655	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.668C>T; p.S223L; 20:33417752-33417752	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1345C>A; p.P449T; 20:33408781-33408781	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation