Cancer metastasis database

Annotation category 5

Gene information

Gene ID 66004
Symbol

LYNX1

Synonymous

SLURP2

Full name

Ly6/neurotoxin 1

Gene description

Ly-6 neurotoxin-like protein 1|SLURP-2|ly-6/neurotoxin-like protein 1|secreted Ly-6/uPAR domain-containing protein 2|secreted Ly-6/uPAR-related protein 2|secreted Ly6/uPAR related protein 2

Cytoband

8q24.3

Gene type

protein-coding

Synonymous

MIM:606110; HGNC:HGNC:29604; Ensembl:ENSG00000180155; HPRD:16201; Vega:OTTHUMG00000164694

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.149G>A; p.R50H; 8:142775598-142775598

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.149G>A; p.R50H; 8:142775598-142775598

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.149G>A; p.R50H; 8:142775598-142775598

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.343G>T; p.G115C; 8:142764658-142764658

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.344G>A; p.G115D; 8:142764657-142764657

 skinmalignant_melanomaSubstitution - Missense

c.119C>T; p.P40L; 8:142775628-142775628

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.371_373delAGA; p.Q124_T125>P; 8:142764628-142764630

 central_nervous_system; brainglioma; astrocytoma_Grade_IVComplex - deletion inframe

c.371_373delAGA; p.Q124_T125>P; 8:142764628-142764630

 central_nervous_system; brainglioma; astrocytoma_Grade_IVComplex - deletion inframe

c.373A>C; p.T125P; 8:142764628-142764628

 breastcarcinomaSubstitution - Missense

c.222C>G; p.C74W; 8:142765073-142765073

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.141G>C; p.M47I; 8:142775606-142775606

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.62T>A; p.L21*; 8:142775685-142775685

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Nonsense

c.285G>T; p.L95F; 8:142764716-142764716

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.113G>A; p.R38H; 8:142775634-142775634

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.311T>C; p.I104T; 8:142764690-142764690

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.195C>T; p.F65F; 8:142765100-142765100

 skinmalignant_melanomaSubstitution - coding silent

c.87C>T; p.N29N; 8:142775660-142775660

 stomachadenocarcinomaSubstitution - coding silent

c.279G>A; p.E93E; 8:142764722-142764722

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.163G>A; p.E55K; 8:142765132-142765132

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.361G>A; p.A121T; 8:142764640-142764640

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.277G>A; p.E93K; 8:142764724-142764724

 skin; armmalignant_melanomaSubstitution - Missense

c.225G>A; p.L75L; 8:142765070-142765070

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.264C>T; p.V88V; 8:142764737-142764737

 skinmalignant_melanomaSubstitution - coding silent

c.338G>T; p.G113V; 8:142764663-142764663

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.153C>T; p.T51T; 8:142775594-142775594

 skinmalignant_melanomaSubstitution - coding silent

c.27G>T; p.L9L; 8:142775931-142775931

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.27G>T; p.L9L; 8:142775931-142775931

 livercarcinomaSubstitution - coding silent

c.327C>T; p.I109I; 8:142764674-142764674

 skinmalignant_melanomaSubstitution - coding silent

c.148C>T; p.R50C; 8:142775599-142775599

 livercarcinomaSubstitution - Missense

c.148C>T; p.R50C; 8:142775599-142775599

 livercarcinomaSubstitution - Missense

c.72C>T; p.H24H; 8:142775675-142775675

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.309C>G; p.H103Q; 8:142764692-142764692

 NSmalignant_melanomaSubstitution - Missense

c.22A>G; p.I8V; 8:142775936-142775936

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.22A>G; p.I8V; 8:142775936-142775936

 livercarcinomaSubstitution - Missense