lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6513
Symbol	SLC2A1
Synonymous	DYT17\|DYT18\|DYT9\|EIG12\|GLUT\|GLUT-1\|GLUT1\|GLUT1DS\|HTLVR\|PED
Full name	solute carrier family 2 (facilitated glucose transporter), member 1
Gene description	glucose transporter type 1, erythrocyte/brain\|hepG2 glucose transporter\|human T-cell leukemia virus (I and II) receptor\|receptor for HTLV-1 and HTLV-2\|solute carrier family 2, facilitated glucose transporter member 1
Cytoband	1p34.2
Gene type	protein-coding
Synonymous	MIM:138140; MIM:143090; HGNC:HGNC:11005; Ensembl:ENSG00000117394; HPRD:00683; Vega:OTTHUMG00000007657

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.51A>C; p.G17G; 1:42943289-42943289	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.179C>T; p.T60M; 1:42931142-42931142	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.586C>G; p.P196A; 1:42929966-42929966	meninges	meningioma	Substitution - Missense
c.695G>A; p.R232H; 1:42929765-42929765	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.97A>C; p.I33L; 1:42943243-42943243	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.97A>C; p.I33L; 1:42943243-42943243	urinary_tract; bladder	carcinoma	Substitution - Missense
c.319G>A; p.A107T; 1:42930823-42930823	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1062G>A; p.A354A; 1:42928944-42928944	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1155C>T; p.P385P; 1:42927728-42927728	skin	malignant_melanoma	Substitution - coding silent
c.224G>A; p.G75E; 1:42931097-42931097	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.739G>A; p.E247K; 1:42929721-42929721	urinary_tract; bladder	carcinoma	Substitution - Missense
c.218C>T; p.S73F; 1:42931103-42931103	skin	malignant_melanoma	Substitution - Missense
c.758G>A; p.R253Q; 1:42929702-42929702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.123G>T; p.E41D; 1:42931198-42931198	liver	carcinoma	Substitution - Missense
c.1334T>C; p.F445S; 1:42927186-42927186	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.258C>T; p.F86F; 1:42931063-42931063	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.258C>T; p.F86F; 1:42931063-42931063	skin	malignant_melanoma	Substitution - coding silent
c.1296C>T; p.Y432Y; 1:42927224-42927224	pancreas	carcinoma	Substitution - coding silent
c.973C>T; p.L325L; 1:42929033-42929033	pancreas	NS	Substitution - coding silent
c.109_110insC; p.Q37fs*52; 1:42943230-42943231	pancreas	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.1333T>C; p.F445L; 1:42927187-42927187	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1333T>C; p.F445L; 1:42927187-42927187	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1333T>C; p.F445L; 1:42927187-42927187	large_intestine; rectum	NS	Substitution - Missense
c.265C>T; p.R89C; 1:42931056-42931056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1215C>T; p.A405A; 1:42927668-42927668	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1399T>C; p.F467L; 1:42927121-42927121	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.694C>T; p.R232C; 1:42929766-42929766	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.694C>T; p.R232C; 1:42929766-42929766	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.462G>A; p.G154G; 1:42930680-42930680	skin	malignant_melanoma	Substitution - coding silent
c.988C>T; p.R330*; 1:42929018-42929018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.612G>T; p.L204L; 1:42929940-42929940	thyroid	other; neoplasm	Substitution - coding silent
c.790C>T; p.R264C; 1:42929670-42929670	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.795C>T; p.S265S; 1:42929665-42929665	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.312C>T; p.F104F; 1:42930830-42930830	oesophagus	carcinoma	Substitution - coding silent
c.1412delG; p.G471fs*>22; 1:42927108-42927108	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1038T>G; p.G346G; 1:42928968-42928968	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1011C>T; p.H337H; 1:42928995-42928995	breast	carcinoma	Substitution - coding silent
c.510C>T; p.I170I; 1:42930632-42930632	skin	malignant_melanoma	Substitution - coding silent
c.624C>T; p.P208P; 1:42929928-42929928	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.624C>T; p.P208P; 1:42929928-42929928	stomach	adenocarcinoma	Substitution - coding silent
c.1182C>T; p.L394L; 1:42927701-42927701	breast	carcinoma	Substitution - coding silent
c.180G>A; p.T60T; 1:42931141-42931141	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.443C>T; p.S148L; 1:42930699-42930699	urinary_tract; bladder	carcinoma	Substitution - Missense
c.45C>T; p.A15A; 1:42943295-42943295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.45C>T; p.A15A; 1:42943295-42943295	thyroid	other; neoplasm	Substitution - coding silent
c.1221A>C; p.A407A; 1:42927662-42927662	skin	malignant_melanoma	Substitution - coding silent
c.1420C>A; p.Q474K; 1:42927100-42927100	skin	malignant_melanoma	Substitution - Missense
c.1099C>T; p.L367L; 1:42927784-42927784	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.973-1G>T; p.?; 1:42929034-42929034	pancreas	NS	Unknown
c.213C>G; p.I71M; 1:42931108-42931108	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.736G>A; p.E246K; 1:42929724-42929724	urinary_tract; bladder	carcinoma	Substitution - Missense
c.603C>T; p.C201C; 1:42929949-42929949	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.339G>A; p.S113S; 1:42930803-42930803	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1196C>A; p.P399Q; 1:42927687-42927687	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.458G>A; p.R153H; 1:42930684-42930684	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1190A>G; p.Q397R; 1:42927693-42927693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.517-1G>A; p.?; 1:42930036-42930036	skin	malignant_melanoma	Unknown
c.131A>G; p.Y44C; 1:42931190-42931190	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.511G>A; p.A171T; 1:42930631-42930631	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.511G>A; p.A171T; 1:42930631-42930631	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.371T>C; p.L124P; 1:42930771-42930771	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.558G>A; p.W186*; 1:42929994-42929994	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.819C>G; p.L273L; 1:42929641-42929641	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.107C>G; p.P36R; 1:42943233-42943233	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.178A>G; p.T60A; 1:42931143-42931143	skin	malignant_melanoma	Substitution - Missense
c.189G>A; p.T63T; 1:42931132-42931132	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.522C>T; p.F174F; 1:42930030-42930030	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.522C>T; p.F174F; 1:42930030-42930030	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.522C>T; p.F174F; 1:42930030-42930030	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.936C>T; p.G312G; 1:42929246-42929246	skin	malignant_melanoma	Substitution - coding silent
c.134A>G; p.N45S; 1:42931187-42931187	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.399C>T; p.C133C; 1:42930743-42930743	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.399C>T; p.C133C; 1:42930743-42930743	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1185C>T; p.F395F; 1:42927698-42927698	breast	carcinoma	Substitution - coding silent
c.1108G>A; p.V370M; 1:42927775-42927775	pancreas	carcinoma	Substitution - Missense
c.639C>T; p.F213F; 1:42929913-42929913	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1014C>T; p.L338L; 1:42928992-42928992	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.639C>T; p.F213F; 1:42929913-42929913	skin	malignant_melanoma	Substitution - coding silent
c.1460G>C; p.G487A; 1:42927060-42927060	oesophagus	carcinoma	Substitution - Missense
c.1405C>T; p.Q469*; 1:42927115-42927115	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.967G>A; p.V323M; 1:42929215-42929215	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.849G>A; p.Q283Q; 1:42929611-42929611	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.295A>G; p.M99V; 1:42930847-42930847	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.313G>A; p.V105M; 1:42930829-42930829	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.313G>A; p.V105M; 1:42930829-42930829	large_intestine; colon	carcinoma	Substitution - Missense
c.152G>A; p.R51H; 1:42931169-42931169	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.89C>A; p.T30N; 1:42943251-42943251	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1095C>A; p.S365S; 1:42927788-42927788	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.894C>T; p.F298F; 1:42929288-42929288	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.653G>A; p.R218H; 1:42929899-42929899	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.243C>T; p.F81F; 1:42931078-42931078	breast	carcinoma	Substitution - coding silent
c.174C>T; p.P58P; 1:42931147-42931147	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation