lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	64946
Symbol	CENPH
Synonymous	-
Full name	centromere protein H
Gene description	CENP-H\|interphase centromere complex protein 35\|kinetochore protein CENP-H
Cytoband	5p15.2
Gene type	protein-coding
Synonymous	MIM:605607; HGNC:HGNC:17268; Ensembl:ENSG00000153044; HPRD:12029; Vega:OTTHUMG00000097816

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.695C>A; p.A232D; 5:69209750-69209750	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.368C>T; p.S123F; 5:69197106-69197106	skin	malignant_melanoma	Substitution - Missense
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.337delA; p.N115fs*16; 5:69197075-69197075	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.313A>T; p.R105W; 5:69195790-69195790	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.314G>T; p.R105M; 5:69195791-69195791	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.730G>T; p.V244F; 5:69209785-69209785	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4G>A; p.E2K; 5:69189638-69189638	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.588G>T; p.K196N; 5:69208296-69208296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.472A>G; p.R158G; 5:69202955-69202955	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.239C>T; p.A80V; 5:69194695-69194695	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.477G>T; p.K159N; 5:69202960-69202960	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.570A>C; p.E190D; 5:69208278-69208278	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.696C>T; p.A232A; 5:69209751-69209751	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.235G>A; p.E79K; 5:69194691-69194691	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.414A>C; p.K138N; 5:69202548-69202548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.604C>T; p.L202L; 5:69208312-69208312	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.234C>T; p.I78I; 5:69194690-69194690	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.336_337insA; p.N115fs*6; 5:69197074-69197075	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.262G>C; p.E88Q; 5:69195739-69195739	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.388delA; p.M130fs*1; 5:69202522-69202522	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.180G>A; p.M60I; 5:69191840-69191840	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.587A>G; p.K196R; 5:69208295-69208295	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.189A>T; p.A63A; 5:69191849-69191849	skin	malignant_melanoma	Substitution - coding silent
c.686A>G; p.E229G; 5:69209741-69209741	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.738G>T; p.M246I; 5:69209793-69209793	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.591C>T; p.I197I; 5:69208299-69208299	skin	malignant_melanoma	Substitution - coding silent
c.62G>T; p.R21L; 5:69189696-69189696	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.487+1G>A; p.?; 5:69202971-69202971	stomach	carcinoma; adenocarcinoma	Unknown
c.251A>T; p.D84V; 5:69195728-69195728	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation